Protein Alignment ppk28 and Asic1

DIOPT Version :9

• Sequence 1: NP_573169.2
• Gene: ppk28 / 32671
• FlyBaseID: FBgn0030795
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: NP_001276720.1
• Gene: Asic1 / 11419
• MGIID: 1194915
• Length: 559
• Species: Mus musculus
• Alignment Length: 577
• Identity: 128/577 - (22%)
• Similarity: 212/577 - (36%)
• Gaps: 166/577 - (28%)

  Fly     9 RRQSGSSGCKKDSESDDDENTICSRAAIKRSVVYYLKNSTLHGLKYIAEESITIPERIFFGLAFV 73
            |:|..||..:::.|.:.:...........|.:|.:..:.||||..::..|....|.:..:.:|||
Mouse    32 RQQQDSSESEEEEEKEKESGMELDEGDSPRDLVAFANSCTLHGASHVFVEGGPGPRQALWAVAFV 96

  Fly    74 LVVILSVFFISNVYVKWSASPIIISTSAKQKLTSNMPFPAITICNLNQALLSKV---DRIGRTST 135
            :.:...:..:.:....:.:.|.:  |...:..|:.:.|||:|.||.|...||::   |.:
Mouse    97 IALGAFLCQVGDRVAYYLSYPHV--TLLDEVATTELVFPAVTFCNTNAVRLSQLSYPDLL----- 154

  Fly   136 NFSLLMGLCDQGGDTTISYIGTWKYFKAILVDVAQP-------------------C---EKMLLY 178
            ..:.::|| |:..|..              |.:|.|                   |   |.||||
Mouse   155 YLAPMLGL-DESDDPG--------------VPLAPPGPEAFSGEPFNLHRFYNRSCHRLEDMLLY 204

  Fly   179 CSF-----GSREEDCSWLFTSILTDDGLCCNFNALHPSYLIRNYSDDVRLETAHPNTRYELIDWT 238
            ||:     |...      |:.:.|..|.|..||:        ......||:|
Mouse   205 CSYCGGPCGPHN------FSVVFTRYGKCYTFNS--------GQDGRPRLKT------------- 242

  Fly   239 PEKGYARNLPEFYFPRTSGGTGIRMGLTVVLNASIAEYYCT------KSMSVGFKVLVHNPAELP 297
                            ..||||  .||.::|:....||...      .|...|.||.:|:..|.|
Mouse   243 ----------------MKGGTG--NGLEIMLDIQQDEYLPVWGETDETSFEAGIKVQIHSQDEPP 289

  Fly   298 KVSNYGFVVTAG-------REARIPIEPVYEDALPTIRSIKKSVRRCLFSDENDLAYYRTYSRKN 355
            .:...||.|..|       :|.|:    :|   ||:......:|..       |..::.:||...
Mouse   290 FIDQLGFGVAPGFQTFVSCQEQRL----IY---LPSPWGTCNAVTM-------DSDFFDSYSITA 340

  Fly   356 CELECEAKLLLRECSCVLYYLPRIDPLARVCGPND-NQCTD-----RVQTEIESSLTNLSCENCW 414
            |.::||.:.|:..|:|.:.::|...|   .|.|.. .:|.|     .|:.:.|..:..:.|
Mouse   341 CRIDCETRYLVENCNCRMVHMPGDAP---YCTPEQYKECADPALDFLVEKDQEYCVCEMPC---- 398

  Fly   415 PGCFELT-YRATLSTASIVSD-------PRFQAGENLPEYIFHGPYSNASEISILHFYYMTNIFR 471
                .|| |...||...|.|.       .:|...|   :||       ...|.:|..::....:.
Mouse   399 ----NLTRYGKELSMVKIPSKASAKYLAKKFNKSE---QYI-------GENILVLDIFFEVLNYE 449

  Fly   472 STTKSEMFGFTEFLSNTGGLLGLFMGFSIFSVIEIFFYITVRPYCASRTLRQRHKRR 528
            :..:.:.:.....|.:.||.:|||:|.||.:|:|:|.|       |...::.|..||
Mouse   450 TIEQKKAYEIAGLLGDIGGQMGLFIGASILTVLELFDY-------AYEVIKHRLCRR 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk28	NP_573169.2	ASC	43..509	CDD:279230	116/522 (22%)
Asic1	NP_001276720.1	ASC	63..541	CDD:295594	122/546 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842202
Domainoid	1	1.000	108	1.000	Domainoid score	I6420
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8693
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3633
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.780