Protein Alignment ppk28 and asic2

DIOPT Version :10

• Sequence 1: NP_573169.2
• Gene: ppk28 / 32671
• FlyBaseID: FBgn0030795
• Length: 606
• Species: Drosophila melanogaster
• Sequence 2: XP_004918663.1
• Gene: asic2 / 100492214
• XenbaseID: XB-GENE-6033380
• Length: 541
• Species: Xenopus tropicalis
• Alignment Length: 514
• Identity: 112/514 - (21%)
• Similarity: 184/514 - (35%)
• Gaps: 122/514 - (23%)

  Fly    44 LKNSTLHGLKYIAEESITIPERIFFGLAFVLVVILSVFFISNVYVKWSASPIIISTSAKQKLTSN 108
            |::..|||||||....:....|.|:.|||...:...:.:.||..:.|.:.|  ..|..:.:.:..
 Frog    45 LQHIKLHGLKYICSPKLAFRHRTFWFLAFFTSLGFFLSWSSNRLLYWLSFP--SHTRVQLEWSKE 107

  Fly   109 MPFPAITICNLNQALLSKVDRIGRTSTNFS---------------LLMGLCDQGGDTTISYIGTW 158
            :.|||:|.||.|..   :..|:.::...|:               :|..|..:........:..:
 Frog   108 LAFPAVTFCNNNPV---RFHRLSKSDLYFAGYWLGLLFANRTARPMLAELLPEDRRKWFQKLADF 169

  Fly   159 KYF----------KAILVDVAQPCEKMLLYCSFGSREEDCS-WLFTSILTDDGLCCNFNALHPSY 212
            :.|          ...:..:....|.|||.|.:  |.|.|. ..|:::.|..|.|..||:
 Frog   170 RLFLPPRNFDGISVGFMDRLGHQLEDMLLSCKY--RGEACGPHNFSTVFTRYGKCYMFNS----- 227

  Fly   213 LIRNYSDDVR--LETAHPNTRYELIDWTPEKGYARNLPEFYFPRTSGGTGIRMGLTVVLNASIAE 275
                 ..|.|  |.|                             ..||.|  .||.::|:....|
 Frog   228 -----GQDGRPVLTT-----------------------------VKGGAG--NGLEIMLDIQQDE 256

  Fly   276 YYC------TKSMSVGFKVLVHNPAELPKVSNYGFVVTAGREARIPIEPVYEDALPTIRSIKKSV 334
            |..      ..:...|.||.:|:.:|.|.:...||.|..|.:..:..:......||:      ..
 Frog   257 YLPIWGDTEETTFEAGVKVQIHSQSEPPFIQELGFGVAPGFQTFVATQEQRLTYLPS------PW 315

  Fly   335 RRCLFSDENDLAYYRTYSRKNCELECEAKLLLRECSCVLYYLPRIDPLARVCGPNDNQCTDRVQT 399
            ..|.|| |....::..||...|.::||.:.::..|.|.:.::|...|.          ||.....
 Frog   316 GACRFS-ELGSDFFPVYSISACRIDCETRYIVENCGCKMVHMPGDAPF----------CTPEQYK 369

  Fly   400 EIESSLTNLSCEN------CWPGCFELTYRATLSTASIVS-------DPRFQAGENLPEYIFHGP 451
            |......:|..|.      |...|....|...||...|.|       :.:|...|   :||.
 Frog   370 ECAEPALDLLAEKDGGNCVCTIPCNVTRYNKELSMVKIPSKTSAKYLEKKFNKSE---KYIL--- 428

  Fly   452 YSNASEISILHFYYMTNIFRSTTKSEMFGFTEFLSNTGGLLGLFMGFSIFSVIEIFFYI 510
                ..|.:|..::....:.:..:.:.:.....|.:.||.:|||:|.||.:::|:|.||
 Frog   429 ----DNILVLDVFFEALNYETIEQRKAYEVAGLLGDIGGQMGLFIGASILTILELFDYI 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk28	NP_573169.2	ASC	43..509	CDD:459966	110/511 (22%)
asic2	XP_004918663.1	ENaC	49..497	CDD:273304	111/510 (22%)