DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4789 and Rabl3

DIOPT Version :9

Sequence 1:	NP_573166.1	Gene:	CG4789 / 32668	FlyBaseID:	FBgn0030792	Length:	274	Species:	Drosophila melanogaster
Sequence 2:	NP_001035964.1	Gene:	Rabl3 / 67657	MGIID:	1914907	Length:	236	Species:	Mus musculus

Alignment Length:	265	Identity:	115/265 - (43%)
Similarity:	163/265 - (61%)	Gaps:	40/265 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAMNNRVRIVVVGDSGVGKTSLTHLITHNEALIRPGWTVGCNIQVKMHPFREGTARECPYFVELF 65
            ||..:||:::|:|||||||:||.||:.||:.|..|.|||||::.:::|.::|||..|..|::||:
Mouse     1 MASLDRVKVLVLGDSGVGKSSLVHLLCHNQVLGNPSWTVGCSVDIRVHDYKEGTPEEKTYYIELW 65

  Fly    66 DVGGSLNH----KNTRSVFYAGIDGIILVHDLTNAKSQRQLIDWLYEIVNKEGKDTNKSNGASMP 126
            |||||:..    |:||:|||..::||||||||||.||.:.|..|..|::|::          ::|
Mouse    66 DVGGSVGSASSVKSTRAVFYNSVNGIILVHDLTNKKSSQNLYRWSLEVLNRD----------AVP 120

  Fly   127 PSPPSPLSSFSTDNLGTDGHILFDMEEFLGATQTPILVMGTKLDLLDE-KRHPKMGVKKPGGIAD 190
                       |..|.|:|.  :|.|:| ...|.|:||:|||||.:.| |||..:  .:...:|:
Mouse   121 -----------TGVLVTNGD--YDREQF-ADNQIPLLVIGTKLDQIHETKRHEVL--IRTAFLAE 169

  Fly   191 KCGAEEIWLNCRNSRSLAAGTTDAVKLSRFFDRVIENRKALRAALAFGVSSSNAVSP-PDRRRFG 254
            ...||||.|:|.|.||.|||:::|||||||||:|||.|...|        ..|.:.. .||:|||
Mouse   170 DFNAEEINLDCTNPRSSAAGSSNAVKLSRFFDKVIEKRYFFR--------EGNQIPGFSDRKRFG 226

  Fly   255 PTSAK 259
            ..:.|
Mouse   227 GGALK 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4789	NP_573166.1	P-loop_NTPase	7..228	CDD:304359	103/225 (46%)
Rabl3	NP_001035964.1	Small GTPase-like	1..235		115/265 (43%)
Rabl3	NP_001035964.1	RabL3	7..210	CDD:206689	104/228 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	129	1.000	Domainoid score	I5283
eggNOG	1	0.900	-	-		E1_2CN0E
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12171
Inparanoid	1	1.050	190	1.000	Inparanoid score	I3871
Isobase	1	0.950	-	0	Normalized mean entropy	S2695
OMA	1	1.010	-	-		QHG49110
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005865
OrthoInspector	1	1.000	-	-		oto91977
orthoMCL	1	0.900	-	-		OOG6_105341
Panther	1	1.100	-	-	LDO	PTHR24073
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3062
SonicParanoid	1	1.000	-	-		X4259
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.810