DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4789 and rabl3

DIOPT Version :9

Sequence 1:	NP_573166.1	Gene:	CG4789 / 32668	FlyBaseID:	FBgn0030792	Length:	274	Species:	Drosophila melanogaster
Sequence 2:	NP_991296.1	Gene:	rabl3 / 403048	ZFINID:	ZDB-GENE-040808-11	Length:	233	Species:	Danio rerio

Alignment Length:	259	Identity:	107/259 - (41%)
Similarity:	151/259 - (58%)	Gaps:	40/259 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAMNNRVRIVVVGDSGVGKTSLTHLITHNEALIRPGWTVGCNIQVKMHPFREGTARECPYFVELF 65
            ||..:||:::|:|||||||:||.||:..|:.|..|.|||||::.|::|.:||||..|..:::||:
Zfish     1 MASLDRVKVLVLGDSGVGKSSLVHLLCQNQVLGNPSWTVGCSVDVRVHDYREGTPEEKAFYIELW 65

  Fly    66 DVGGSLNH----KNTRSVFYAGIDGIILVHDLTNAKSQRQLIDWLYEIVNKEGKDTN--KSNGAS 124
            |||||:..    |:||:|||..::||||||||||.||.:.|..|..|.::|:...|.  .|||.
Zfish    66 DVGGSVGSASSVKSTRAVFYNSVNGIILVHDLTNKKSSQNLYRWSLEALSKDSSPTGIIVSNGD- 129

  Fly   125 MPPSPPSPLSSFSTDNLGTDGHILFDMEEFLGATQTPILVMGTKLDLLDEKRHPKMGVKKPGGIA 189
                                    :|.|:| .....|:|::|||.|.:.|.:...: :.:...::
Zfish   130 ------------------------YDREQF-AENAVPLLLIGTKFDQIPENKRNDV-LTRTAFLS 168

  Fly   190 DKCGAEEIWLNCRNSRSLAAGTTDAVKLSRFFDRVIENRKALRAALAFGVSSSNAVSPPDRRRF 253
            :...||||.|:|.|.|.||||:::|||||||||:|||.|...|       ..|...|..|||||
Zfish   169 EDFNAEEINLDCTNPRYLAAGSSNAVKLSRFFDKVIEKRYFTR-------DPSQMQSFTDRRRF 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4789	NP_573166.1	P-loop_NTPase	7..228	CDD:304359	95/226 (42%)
rabl3	NP_991296.1	Small GTPase-like	1..233		107/259 (41%)
rabl3	NP_991296.1	RabL3	7..210	CDD:206689	96/229 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	124	1.000	Domainoid score	I5506
eggNOG	1	0.900	-	-		E1_2CN0E
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12171
Inparanoid	1	1.050	179	1.000	Inparanoid score	I4003
OMA	1	1.010	-	-		QHG49110
OrthoDB	1	1.010	-	-		D1269342at2759
OrthoFinder	1	1.000	-	-		FOG0005865
OrthoInspector	1	1.000	-	-		oto41191
orthoMCL	1	0.900	-	-		OOG6_105341
Panther	1	1.100	-	-	LDO	PTHR24073
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3062
SonicParanoid	1	1.000	-	-		X4259
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.910