DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sap30 and SAP30

DIOPT Version :9

Sequence 1:	NP_001285352.1	Gene:	Sap30 / 32664	FlyBaseID:	FBgn0030788	Length:	173	Species:	Drosophila melanogaster
Sequence 2:	NP_003855.1	Gene:	SAP30 / 8819	HGNCID:	10532	Length:	220	Species:	Homo sapiens

Alignment Length:	151	Identity:	81/151 - (53%)
Similarity:	111/151 - (73%)	Gaps:	4/151 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 QTCCLIDDMERCRNQAGYASYSKRIQKTVAQKRLKLSSDPAAQHIYICDHHKERIQSVRTKRRRK 82
            |.|||.:|.|||...||.||:||||||:::||::|:..|.:|:|:||||:||..|||||.:|:||
Human    65 QLCCLREDGERCGRAAGNASFSKRIQKSISQKKVKIELDKSARHLYICDYHKNLIQSVRNRRKRK 129

  Fly    83 DSEDDSNET---DTDLHEFPDLYQLGVSTLRRYKRHFKVQTRQGMKRAQLADTIMKHFKTIPIKE 144
            .|:||..::   |.|..|. |||||.|:||||||||||:.||.|:.:|||.:.:..||::||:.|
Human   130 GSDDDGGDSPVQDIDTPEV-DLYQLQVNTLRRYKRHFKLPTRPGLNKAQLVEIVGCHFRSIPVNE 193

  Fly   145 KEIITFFVYMVKMGSNKLDQK 165
            |:.:|:|:|.||...||.|.|
Human   194 KDTLTYFIYSVKNDKNKSDLK 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sap30	NP_001285352.1	zf-SAP30	16..86	CDD:404707	39/67 (58%)
Sap30	NP_001285352.1	SAP30_Sin3_bdg	104..156	CDD:404708	27/51 (53%)
SAP30	NP_003855.1	Interaction with NCOR1. /evidence=ECO:0000250	1..129		36/63 (57%)
		zf-SAP30	65..133	CDD:404707	39/67 (58%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	123..143		7/19 (37%)
		Interaction with SIN3A. /evidence=ECO:0000250	130..220		43/86 (50%)
		SAP30_Sin3_bdg	153..205	CDD:404708	27/51 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143477
Domainoid	1	1.000	94	1.000	Domainoid score	I7487
eggNOG	1	0.900	-	-		E1_28PSY
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	190	1.000	Inparanoid score	I3889
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48250
OrthoDB	1	1.010	-	-		D1520155at2759
OrthoFinder	1	1.000	-	-		FOG0004254
OrthoInspector	1	1.000	-	-		otm42090
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13286
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2991
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.870