DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sap30 and sap30l

DIOPT Version :9

Sequence 1:	NP_001285352.1	Gene:	Sap30 / 32664	FlyBaseID:	FBgn0030788	Length:	173	Species:	Drosophila melanogaster
Sequence 2:	NP_001017141.1	Gene:	sap30l / 549895	XenbaseID:	XB-GENE-960202	Length:	181	Species:	Xenopus tropicalis

Alignment Length:	174	Identity:	97/174 - (55%)
Similarity:	128/174 - (73%)	Gaps:	12/174 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 NGFSTGEEDSRG--------HTDQTCCLIDDMERCRNQAGYASYSKRIQKTVAQKRLKLSSDPAA 59
            ||||| |||||.        ...|||||||..|||...||.||:|||:||:::||:|||..|.:.
Frog     2 NGFST-EEDSRDGPPAQAAPFFGQTCCLIDGGERCPRPAGNASFSKRVQKSISQKKLKLDIDKSV 65

  Fly    60 QHIYICDHHKERIQSVRTKRRRKDSED--DSNETDTDLHEFPDLYQLGVSTLRRYKRHFKVQTRQ 122
            :|:||||.||..|||||.||:||.|:|  ||.|.:||:.|. ||:||.|:|||||||::|:|||.
Frog    66 RHLYICDFHKNYIQSVRNKRKRKTSDDGGDSPEHETDVPEV-DLFQLQVNTLRRYKRYYKLQTRP 129

  Fly   123 GMKRAQLADTIMKHFKTIPIKEKEIITFFVYMVKMGSNKLDQKN 166
            |:.:||||:|:.:||:.||:.|||.:.:|:||||...::||||:
Frog   130 GLNKAQLAETVSRHFRNIPVNEKETLAYFIYMVKSNRSRLDQKS 173

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sap30	NP_001285352.1	zf-SAP30	16..86	CDD:404707	42/69 (61%)
Sap30	NP_001285352.1	SAP30_Sin3_bdg	104..156	CDD:404708	29/51 (57%)
sap30l	NP_001017141.1	zf-SAP30	21..92	CDD:372766	42/70 (60%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	82..103		11/20 (55%)
		Nuclear localization signal (NLS). /evidence=ECO:0000250\|UniProtKB:Q9HAJ7	83..88		2/4 (50%)
		Important for DNA and phosphoinositide binding. /evidence=ECO:0000250\|UniProtKB:Q9HAJ7	85..87		1/1 (100%)
		SAP30_Sin3_bdg	111..163	CDD:372767	29/51 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	96	1.000	Domainoid score	I7209
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11632
Inparanoid	1	1.050	189	1.000	Inparanoid score	I3774
OMA	1	1.010	-	-		QHG48250
OrthoDB	1	1.010	-	-		D1520155at2759
OrthoFinder	1	1.000	-	-		FOG0004254
OrthoInspector	1	1.000	-	-		otm49322
Panther	1	1.100	-	-	LDO	PTHR13286
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4744
SonicParanoid	1	1.000	-	-		X2991
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110