DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sap30 and sap30l

DIOPT Version :9

Sequence 1:	NP_001285352.1	Gene:	Sap30 / 32664	FlyBaseID:	FBgn0030788	Length:	173	Species:	Drosophila melanogaster
Sequence 2:	NP_999868.1	Gene:	sap30l / 327079	ZFINID:	ZDB-GENE-030131-5287	Length:	178	Species:	Danio rerio

Alignment Length:	172	Identity:	94/172 - (54%)
Similarity:	126/172 - (73%)	Gaps:	10/172 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 NGFSTGEEDSRG------HTDQTCCLIDDMERCRNQAGYASYSKRIQKTVAQKRLKLSSDPAAQH 61
            ||||| ||||..      ...|:||||:|.|||...||.||:||||||:::|::|||..|.:.:|
Zfish     2 NGFST-EEDSHDGPPAPPFFGQSCCLIEDAERCGRPAGNASFSKRIQKSISQRKLKLDIDKSVRH 65

  Fly    62 IYICDHHKERIQSVRTKRRRKDSEDDSNETDTDLHEFP--DLYQLGVSTLRRYKRHFKVQTRQGM 124
            :||||.||..|||||.||:||.|:|.....|.:: |.|  ||:||.|:||||||||:|:|||.|:
Zfish    66 LYICDFHKNFIQSVRNKRKRKTSDDGGESPDHEV-EVPEVDLFQLQVNTLRRYKRHYKIQTRPGL 129

  Fly   125 KRAQLADTIMKHFKTIPIKEKEIITFFVYMVKMGSNKLDQKN 166
            .:||||:|:.:||:.||:.|||.:|:|:||||...::||||:
Zfish   130 NKAQLAETVSRHFRNIPVNEKETLTYFIYMVKSSKSRLDQKS 171

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sap30	NP_001285352.1	zf-SAP30	16..86	CDD:404707	41/69 (59%)
Sap30	NP_001285352.1	SAP30_Sin3_bdg	104..156	CDD:404708	31/51 (61%)
sap30l	NP_999868.1	zf-SAP30	20..90	CDD:290577	41/69 (59%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	80..99		8/18 (44%)
		Nuclear localization signal (NLS). /evidence=ECO:0000250\|UniProtKB:Q9HAJ7	81..86		2/4 (50%)
		Important for DNA and phosphoinositide binding. /evidence=ECO:0000250\|UniProtKB:Q9HAJ7	83..85		1/1 (100%)
		SAP30_Sin3_bdg	110..158	CDD:290578	28/47 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576352
Domainoid	1	1.000	95	1.000	Domainoid score	I7358
eggNOG	1	0.900	-	-		E1_28PSY
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11632
Inparanoid	1	1.050	189	1.000	Inparanoid score	I3883
OMA	1	1.010	-	-		QHG48250
OrthoDB	1	1.010	-	-		D1520155at2759
OrthoFinder	1	1.000	-	-		FOG0004254
OrthoInspector	1	1.000	-	-		otm25695
orthoMCL	1	0.900	-	-		OOG6_106692
Panther	1	1.100	-	-	LDO	PTHR13286
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4744
SonicParanoid	1	1.000	-	-		X2991
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800