DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9609 and PZF1

DIOPT Version :9

Sequence 1:	NP_573161.1	Gene:	CG9609 / 32663	FlyBaseID:	FBgn0030787	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_015512.1	Gene:	PZF1 / 856316	SGDID:	S000006390	Length:	429	Species:	Saccharomyces cerevisiae

Alignment Length:	433	Identity:	92/433 - (21%)
Similarity:	156/433 - (36%)	Gaps:	163/433 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 KKHACSYEGCDKTYSIVTHLKRHLRSTHERPESAAKKTVKCALEECSKMFISVSNMTRHMRETHE 127
            |.:.|.|:||||.::..:.|..|..|.|:     ..:..:|  ::|:|.|:..|::.||: .||.
Yeast    47 KTYFCDYDGCDKAFTRPSILTEHQLSVHQ-----GLRAFQC--DKCAKSFVKKSHLERHL-YTHS 103

  Fly   128 SPKVYPCSQCSAKFSQKLKLKRHEI-----------------------REHTLE---YPYSCSKC 166
            ..|.:.||.|....:.:.:|||||:                       |.|.|.   :..:|..|
Yeast   104 DTKPFQCSYCGKGVTTRQQLKRHEVTHTKSFICPEEGCNLRFYKHPQLRAHILSVHLHKLTCPHC 168

  Fly   167 SRGFYQQWQCQS-----HEPSCK-LYEC--PGCPLQFDKWTLYTKHCR----------------- 206
            ::.|.:.::.::     |:|..: .|:|  .||..:|..|:....|.:
Yeast   169 NKSFQRPYRLRNHISKHHDPEVENPYQCTFAGCCKEFRIWSQLQSHIKNDHPKLKCPICSKPCVG 233

  Fly   207 ------------DSLHGKNRHKCDRC-DSAFDKPSELKRH-----------LEVKHK-----EAA 242
                        |||..|| .||..| |.:|.:..:|..|           ||:|:|     :..
Yeast   234 ENGLQMHMIIHDDSLVTKN-WKCHICPDMSFSRKHDLLTHYGSIHTEEDIPLELKYKISDIQQLV 297

  Fly   243 QTD--ECATSFTCNEEGCGKSYSYLRNLRQ---------------------------HMLTAHSG 278
            |..  :...|...||:...|..:.||..|:                           ::|....|
Yeast   298 QDHGVQLGNSKHSNEQDEEKISNRLRKRRKLTENNNVEFLQNEVDLEKRLESGENGLNLLLNTVG 362

  Fly   279 RRFECQALDCGRCFSSAQNLARHLLRDHKDGATKKELKAKKKDKSKTGEGGKTKSTSRKRRRDAG 343
            |::.|...:|.|.|.:.:...:|:                  ||.|..|
Yeast   363 RKYRCFYNNCSRTFKTKEKYEKHI------------------DKHKVHE---------------- 393

  Fly   344 RSKHSRLSKLACLQLDKEDDEAV---RERQPLVLEKITQSLKD 383
                   .||..|| :||:::.:   ..::|.:::|.|||..|
Yeast   394 -------LKLKILQ-EKEENKTLVDQNHKEPFIIQKETQSAGD 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9609	NP_573161.1	C2H2 Zn finger	40..59	CDD:275368
		zf-C2H2_8	67..150	CDD:292531	25/82 (30%)
		C2H2 Zn finger	67..90	CDD:275368	9/22 (41%)
		C2H2 Zn finger	106..126	CDD:275368	6/19 (32%)
		C2H2 Zn finger	134..155	CDD:275368	9/43 (21%)
		C2H2 Zn finger	188..210	CDD:275368	8/52 (15%)
		C2H2 Zn finger	217..237	CDD:275368	8/31 (26%)
		C2H2 Zn finger	253..276	CDD:275368	7/49 (14%)
		C2H2 Zn finger	283..302	CDD:275368	4/18 (22%)
PZF1	NP_015512.1	COG5048	46..427	CDD:227381	91/430 (21%)
		C2H2 Zn finger	54..74	CDD:275368	7/19 (37%)
		C2H2 Zn finger	82..102	CDD:275368	7/22 (32%)
		C2H2 Zn finger	110..130	CDD:275368	8/19 (42%)
		C2H2 Zn finger	136..155	CDD:275368	1/18 (6%)
		C2H2 Zn finger	165..185	CDD:275368	3/19 (16%)
		C2H2 Zn finger	196..216	CDD:275368	6/19 (32%)
		C2H2 Zn finger	224..244	CDD:275368	0/19 (0%)
		C2H2 Zn finger	255..277	CDD:275368	6/21 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000