DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9609 and 42Sp43

DIOPT Version :9

Sequence 1:	NP_573161.1	Gene:	CG9609 / 32663	FlyBaseID:	FBgn0030787	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001016094.1	Gene:	42Sp43 / 548848	XenbaseID:	XB-GENE-5898342	Length:	365	Species:	Xenopus tropicalis

Alignment Length:	324	Identity:	84/324 - (25%)
Similarity:	122/324 - (37%)	Gaps:	53/324 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 METALEEFKQRQGRRNSIGSAKYACSMPKCEATFKRLDQLDRHEYHHTGIKKHACSYEGCDKTYS 77
            |.|..:|.|.|.......|...:.||...|...|.|..|:.:|...|..:||::||..||...::
Frog    23 MATYRKEGKLRDHMAGHSGQKPWKCSKKDCGKVFARKRQIQKHIKCHLILKKYSCSAAGCKMAFN 87

  Fly    78 IVTHLKRHLRSTHERPESAAKKTVKCALEECSKMFISVSNMTRHMRE-THESPKVYPCSQCSAKF 141
            |...||.|....|     .....:||::..|.:.|...|.:..|:.| :.||..|.....|..|.
Frog    88 IKKSLKSHTLYKH-----GDALPLKCSVSGCKRSFRKKSALRIHLSEHSKESLSVCDLPGCGWKS 147

  Fly   142 SQKLKLKRHEIREHTLEYPYSCSKCSRGFYQQWQCQSHEPSCKLYECPGCPLQFDKWTLYTKHCR 206
            :...:||.|: |.|.   .|.|              |||         ||......||....|.
Frog   148 TSATELKAHQ-RRHG---GYRC--------------SHE---------GCQTISPTWTALQTHL- 184

  Fly   207 DSLHGKNRH----KCDRCDSAFDKPSELKRHLEVKHKEAAQTDECATSFTCNEEGCGKSYSYLRN 267
                  .:|    :|..|...|.|.|.|:||       .|..|:......|..:.|.|:::.:.|
Frog   185 ------EKHPLELQCATCKKPFKKASALRRH-------KATHDKKPLKLPCPRQDCDKTFNTVFN 236

  Fly   268 LRQHMLTAH-SGRRFECQALDCGRCFSSAQNLARHLLRDHKDGATKKELKAKKKDKSKTGEGGK 330
            |..|:...| ..:...|....|.|.|:..::|.|||: .|.....|.:||..::.....|.|.:
Frog   237 LTHHVRKVHLCLQTHRCYHAGCNRSFAMRESLLRHLV-VHDPERKKLKLKLGRRPPKFRGRGAR 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9609	NP_573161.1	C2H2 Zn finger	40..59	CDD:275368	5/18 (28%)
		zf-C2H2_8	67..150	CDD:292531	23/83 (28%)
		C2H2 Zn finger	67..90	CDD:275368	8/22 (36%)
		C2H2 Zn finger	106..126	CDD:275368	5/20 (25%)
		C2H2 Zn finger	134..155	CDD:275368	6/20 (30%)
		C2H2 Zn finger	188..210	CDD:275368	5/21 (24%)
		C2H2 Zn finger	217..237	CDD:275368	8/19 (42%)
		C2H2 Zn finger	253..276	CDD:275368	6/22 (27%)
		C2H2 Zn finger	283..302	CDD:275368	6/18 (33%)
42Sp43	NP_001016094.1	C2H2 Zn finger	17..39	CDD:275368	5/15 (33%)
		COG5048	<40..160	CDD:227381	36/125 (29%)
		C2H2 Zn finger	50..69	CDD:275368	5/18 (28%)
		C2H2 Zn finger	77..100	CDD:275368	8/22 (36%)
		C2H2 Zn finger	108..130	CDD:275368	5/21 (24%)
		C2H2 Zn finger	138..160	CDD:275368	6/22 (27%)
		C2H2 Zn finger	193..213	CDD:275368	9/26 (35%)
		C2H2 Zn finger	222..245	CDD:275368	6/22 (27%)
		C2H2 Zn finger	253..275	CDD:275368	8/22 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11955
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	141	1.000	Inparanoid score	I4375
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D500805at33208
OrthoFinder	1	1.000	-	-		FOG0004124
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.060