DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9609 and CG3281

DIOPT Version :9

Sequence 1:	NP_573161.1	Gene:	CG9609 / 32663	FlyBaseID:	FBgn0030787	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_650132.1	Gene:	CG3281 / 41445	FlyBaseID:	FBgn0260741	Length:	538	Species:	Drosophila melanogaster

Alignment Length:	305	Identity:	73/305 - (23%)
Similarity:	118/305 - (38%)	Gaps:	82/305 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 EEFKQRQ-GRRNSIGSAK-------YACSMPKCEATFKRLDQLDRH------------------E 56
            :|.:.|: .|.:.:||..       |.|::  |...|.:.:.|.||                  |
  Fly   178 DEIENRELSRPSQLGSRLNHSANFIYKCAV--CPRVFAKSESLTRHFSQAHKLTADVAAMKLANE 240

  Fly    57 YHHTGIKKHACSYEGCDKTYSIVTHLKRHLRSTH---------ERPESAAKKTVKCALEECSKMF 112
            ...||:    .:.|.|.:|:.....|:||:::.|         |..:::|:|.: ....:|....
  Fly   241 SCGTGL----LTCEHCPRTFKRQDTLRRHMQAFHPDAIALEPEETTDNSARKRI-AKRRDCPHCG 300

  Fly   113 IS--VSNMTRHMRETHESPKVYPCSQCSAKFSQKLKLKRHEIREHTLEYPYSCSKCSRGFYQQWQ 175
            :|  ||::|.|:|. |.....|.|.||...|.:...|..| :|:||.|.|..|..||:.|..|
  Fly   301 LSFPVSSLTIHIRR-HTGDNPYKCDQCEKAFPRSQDLSLH-MRQHTGERPSECKICSKKFISQ-- 361

  Fly   176 CQSHEPSCKLYECPGCPLQFDKWTLYTKHCRDSLH-GKNRHKCDRCDSAFDKPSELKRHLEVKH- 238
                                   ....:|.|  || |:..:.|..|..:|.:.::||.|:. :|
  Fly   362 -----------------------NKLARHMR--LHTGQRPYSCKMCSKSFVQSNDLKIHMR-RHT 400

  Fly   239 -KEAAQTDECATSFTCNEEGCGKSYSYLRNLRQHMLTAHSGRRFE 282
             :...|...|..||.     ||...:..||.:.|::....|...|
  Fly   401 GERPYQCGVCGESFV-----CGSHLNIHRNRKGHLIAVIPGNEVE 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9609	NP_573161.1	C2H2 Zn finger	40..59	CDD:275368	6/36 (17%)
		zf-C2H2_8	67..150	CDD:292531	24/93 (26%)
		C2H2 Zn finger	67..90	CDD:275368	6/22 (27%)
		C2H2 Zn finger	106..126	CDD:275368	7/21 (33%)
		C2H2 Zn finger	134..155	CDD:275368	7/20 (35%)
		C2H2 Zn finger	188..210	CDD:275368	2/21 (10%)
		C2H2 Zn finger	217..237	CDD:275368	6/19 (32%)
		C2H2 Zn finger	253..276	CDD:275368	5/22 (23%)
		C2H2 Zn finger	283..302	CDD:275368	73/305 (24%)
CG3281	NP_650132.1	zf-AD	14..92	CDD:285071
		C2H2 Zn finger	205..226	CDD:275368	6/22 (27%)
		C2H2 Zn finger	249..266	CDD:275368	5/16 (31%)
		COG5048	<294..>391	CDD:227381	33/125 (26%)
		C2H2 Zn finger	296..315	CDD:275368	7/19 (37%)
		zf-H2C2_2	307..330	CDD:290200	8/23 (35%)
		C2H2 Zn finger	323..343	CDD:275368	7/20 (35%)
		zf-H2C2_2	335..358	CDD:290200	10/23 (43%)
		C2H2 Zn finger	351..371	CDD:275368	7/46 (15%)
		zf-H2C2_2	364..388	CDD:290200	8/25 (32%)
		C2H2 Zn finger	379..399	CDD:275368	6/20 (30%)
		zf-H2C2_2	391..416	CDD:290200	8/30 (27%)
		C2H2 Zn finger	407..424	CDD:275368	5/21 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100