DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9609 and si:dkey-156n14.3

DIOPT Version :9

Sequence 1:	NP_573161.1	Gene:	CG9609 / 32663	FlyBaseID:	FBgn0030787	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	XP_002662446.2	Gene:	si:dkey-156n14.3 / 326091	ZFINID:	ZDB-GENE-030131-4816	Length:	1231	Species:	Danio rerio

Alignment Length:	351	Identity:	103/351 - (29%)
Similarity:	150/351 - (42%)	Gaps:	46/351 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 GRRNSIGSAKYACSMPKCEATFKRLDQLDRHEYHHTGIKK-HACSYEGCDKTYSIVTHLKRHLRS 88
            |....:..|||.|..|.|.:||.....|..|...||..:: ..|:.||||.:::....|||||:|
Zfish   478 GMTKKVSLAKYRCPQPGCSSTFDTRQNLKIHLVVHTEDQRPFKCTVEGCDWSFTTSYKLKRHLQS 542

  Fly    89 THERPESAAKKTVKCALEECSKMFISVSNMTRHMRETHESPKVYPCSQCSAKFSQKLKLKRHEIR 153
             |::     .:..||..|.|.:.|.:|.|:..|:| ||:....:.|..||.:|....:|..|:..
Zfish   543 -HDK-----VRPYKCEWENCGRRFTTVYNLKAHVR-THDQENAFVCEVCSERFRTATRLSNHQRT 600

  Fly   154 EHTLEYPYSCS--KCSRGFYQQWQCQSHEPS----CKLYEC--PGCPLQFDKWTLYTKHCRDSLH 210
            ....|.|:.|.  .|.:.|.......||..:    ...:.|  |||..::|      |.||..:|
Zfish   601 HFEPERPHKCEFPGCEKTFITFSALFSHNRTHFREMAQFTCTYPGCDKRYD------KACRLKIH 659

  Fly   211 -----GKNRHKC--DRCDSAFDKPSELKRHLEVKHKEAAQTDECATSFTCNEEGCGKSYSYLRNL 268
                 |:....|  |.|...|...|:|.|| :.||.:..:       |.|.|||||||::...:|
Zfish   660 LRSHTGERPFVCDSDSCGWTFTSMSKLLRH-KRKHDDDRR-------FACLEEGCGKSFTRAEHL 716

  Fly   269 RQHMLTAHSGRRFECQALDCGRCFSSAQNLARHLLRDHKDGATKKELKAKKKDKSKTGEGGKTKS 333
            :.|.:|....:.|||....|...||:..:|..|..:..:||.:.         :|:....|.||.
Zfish   717 KGHSITHLGTKPFECPVEGCNAKFSARSSLYIHSKKHKQDGVSL---------RSRCPVAGCTKH 772

  Fly   334 TSRKRRRDAGRSKHSRLSKLACLQLD 359
            .|.:........||..||.....|||
Zfish   773 FSSRSSLKTHMLKHHNLSPDVLSQLD 798

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9609	NP_573161.1	C2H2 Zn finger	40..59	CDD:275368	6/18 (33%)
		zf-C2H2_8	67..150	CDD:292531	28/82 (34%)
		C2H2 Zn finger	67..90	CDD:275368	11/22 (50%)
		C2H2 Zn finger	106..126	CDD:275368	7/19 (37%)
		C2H2 Zn finger	134..155	CDD:275368	6/20 (30%)
		C2H2 Zn finger	188..210	CDD:275368	8/23 (35%)
		C2H2 Zn finger	217..237	CDD:275368	8/21 (38%)
		C2H2 Zn finger	253..276	CDD:275368	11/22 (50%)
		C2H2 Zn finger	283..302	CDD:275368	5/18 (28%)
si:dkey-156n14.3	XP_002662446.2	zf-C2H2_8	<480..541	CDD:318181	21/60 (35%)
		C2H2 Zn finger	490..512	CDD:275368	7/21 (33%)
		zf-C2H2_8	521..597	CDD:318181	28/82 (34%)
		C2H2 Zn finger	521..543	CDD:275368	11/22 (50%)
		C2H2 Zn finger	551..573	CDD:275368	8/22 (36%)
		C2H2 Zn finger	581..601	CDD:275368	6/19 (32%)
		COG5048	<595..782	CDD:227381	55/209 (26%)
		C2H2 Zn finger	610..632	CDD:275368	5/21 (24%)
		C2H2 Zn finger	644..663	CDD:275368	8/24 (33%)
		C2H2 Zn finger	671..693	CDD:275368	8/22 (36%)
		C2H2 Zn finger	701..723	CDD:275368	10/21 (48%)
		C2H2 Zn finger	731..753	CDD:275368	6/21 (29%)
		C2H2 Zn finger	764..786	CDD:275368	4/21 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000