DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9609 and CG3032

DIOPT Version :9

Sequence 1:	NP_573161.1	Gene:	CG9609 / 32663	FlyBaseID:	FBgn0030787	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001284974.1	Gene:	CG3032 / 31648	FlyBaseID:	FBgn0029928	Length:	431	Species:	Drosophila melanogaster

Alignment Length:	332	Identity:	84/332 - (25%)
Similarity:	133/332 - (40%)	Gaps:	62/332 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 PPGTQIASDSDM--ETALEEFKQR----QGRRNSIGSAKYACSMPKCEATFKRLDQLDRH--EYH 58
            ||  :.|.|.|.  |.|::..|..    :|.||::     .||:  |..:|.....|..|  :.|
  Fly   124 PP--EPAPDPDPIDEPAIKSDKSPRKSFRGSRNTL-----KCSV--CRRSFAHQITLAAHIRKVH 179

  Fly    59 HTGIKKHACSYEGCDKTYSIVTHLKRHLRSTHERPESAAKKTVKCALEECSKMFISVSNMTRHMR 123
            ....:...|  :.|:|.||.:..|..|:|..|...|    :...|....|.:::.|...|.:|.|
  Fly   180 EGSKRPFQC--DQCEKAYSFMGGLYTHIREVHAPKE----RRHPCDQPGCERIYTSRIAMQKHKR 238

  Fly   124 ETHESP------KVYPCSQCSAKFSQKLKLKRHEIREHTLE-----------YPYSCSKCSRGFY 171
            ..| ||      |.:.|.||.|.|:|...||.|...:|..|           ..:.|..|.:.|:
  Fly   239 LKH-SPRDRDALKKFICEQCGASFNQSANLKYHLKTKHPTEDEVAAREGGAGERHFCDICQKEFH 302

  Fly   172 QQW-----QCQSHEPSCKL-YECPGCPLQFDKWTLYTKHCRDSLHGKNRHKCDRCDSAFDKPSEL 230
            .::     ..|.||...:| :||..|..:..|..:..:|.  .:|..::..|:.|...|.:..||
  Fly   303 SRYTLKYHTLQQHEVQEELPHECQVCGRRMAKKFMLLQHM--LMHSNDKLPCEHCGRRFARRFEL 365

  Fly   231 KRHLEVKHKEAAQTDECATSFTCNEEGCGKSYSYLRNLRQHMLTAHSGRR-FECQALDCGRCFSS 294
            :.|:...|.:       ...|.|:.  |.:|::..:.||.|.. .|:|.: :.|..  ||:.|..
  Fly   366 EAHVRAVHLK-------LKPFPCHH--CPESFASRKTLRHHEY-IHTGEKPYICDT--CGQAFRQ 418

  Fly   295 AQNLARH 301
            ...|..|
  Fly   419 QTCLKNH 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9609	NP_573161.1	C2H2 Zn finger	40..59	CDD:275368	4/20 (20%)
		zf-C2H2_8	67..150	CDD:292531	28/88 (32%)
		C2H2 Zn finger	67..90	CDD:275368	8/22 (36%)
		C2H2 Zn finger	106..126	CDD:275368	5/19 (26%)
		C2H2 Zn finger	134..155	CDD:275368	9/20 (45%)
		C2H2 Zn finger	188..210	CDD:275368	4/21 (19%)
		C2H2 Zn finger	217..237	CDD:275368	6/19 (32%)
		C2H2 Zn finger	253..276	CDD:275368	6/22 (27%)
		C2H2 Zn finger	283..302	CDD:275368	6/19 (32%)
CG3032	NP_001284974.1	zf-AD	13..95	CDD:285071
		C2H2 Zn finger	158..179	CDD:275368	6/22 (27%)
		C2H2 Zn finger	188..209	CDD:275368	8/22 (36%)
		C2H2 Zn finger	218..239	CDD:275368	5/20 (25%)
		C2H2 Zn finger	254..275	CDD:275368	9/20 (45%)
		C2H2 Zn finger	294..315	CDD:275368	4/20 (20%)
		C2H2 Zn finger	325..345	CDD:275368	4/21 (19%)
		C2H2 Zn finger	352..373	CDD:275368	6/20 (30%)
		C2H2 Zn finger	381..401	CDD:275368	6/22 (27%)
		C2H2 Zn finger	409..429	CDD:275368	6/19 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100