DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9609 and Zfp65

DIOPT Version :9

Sequence 1:	NP_573161.1	Gene:	CG9609 / 32663	FlyBaseID:	FBgn0030787	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	XP_030103107.1	Gene:	Zfp65 / 235907	MGIID:	107769	Length:	400	Species:	Mus musculus

Alignment Length:	362	Identity:	94/362 - (25%)
Similarity:	139/362 - (38%)	Gaps:	78/362 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 TALEEFKQRQG-RRNSI-----GSAKYACSMPKCEATFKRLDQLDRHE----------------- 56
            |.||:.::..| :|...     |...|.|:  :|...|:.......|:
Mouse    65 TCLEKIQETSGVKRGGAPFMLPGGKCYTCT--ECGKIFEWKKVFQNHQMLDLRMNPYKCEECAKS 127

  Fly    57 YH-----------HTGIKKHACSYEGCDKTYSIVTHLKRH-LRSTHERPESAAKKTVKCALEECS 109
            :|           |||.|.:.|  |.|.|.:.|...|.:| :..|.|:|       .||.:  |.
Mouse   128 FHSPSLSSKESRIHTGGKPYKC--EVCGKAFCIPLLLSKHKIIHTVEKP-------YKCDI--CG 181

  Fly   110 KMFISVSNMTRHMRETHESPKVYPCSQCSAKFSQKLKLKRHEIREHTLEYPYSCSKCSRGFYQQW 174
            |.|...|.::|| ::.|...|.|.|..|...|.....|..|: |.||.|.||.|.:|.:.|....
Mouse   182 KAFQYPSKLSRH-KQIHSEEKPYKCEVCGMAFHFPSLLLVHK-RIHTGEKPYKCEECGKAFRNSS 244

  Fly   175 QCQSHE---PSCKLYECPGCPLQFDKWTLYTKHCRDSLH-GKNRHKCDRCDSAFDKPSELKRHLE 235
            ....|:   ...|.|:|..|...|...:....|  ..:| |:..:||:.|..||..||.|.:|..
Mouse   245 FLSKHKIIHRGEKPYKCEVCGKDFHYPSRLYNH--KKIHSGEKPYKCELCGKAFCFPSSLSKHKR 307

  Fly   236 VKHKEAAQTDECATSFTCNEEGCGKSYSYLRNLRQHMLTAHSGRR-FECQALDCGRCFSSAQNLA 299
            :...|        ..:.|.|  |.|.:.||.:|.:|.: .|:|.: ::|..  ||:.|.....|:
Mouse   308 IHTGE--------KPYKCKE--CEKPFCYLSSLSKHKI-IHTGEKPYKCDL--CGKAFRYPSLLS 359

  Fly   300 RHLLRDHKDGATKKELKAK--------KKDKSKTGEG 328
            .|.:....:...|.|:..|        ||.|...|.|
Mouse   360 EHKVIHTGNKPYKCEVCGKAFHFSSQLKKHKKIHGAG 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9609	NP_573161.1	C2H2 Zn finger	40..59	CDD:275368	4/46 (9%)
		zf-C2H2_8	67..150	CDD:292531	25/83 (30%)
		C2H2 Zn finger	67..90	CDD:275368	7/23 (30%)
		C2H2 Zn finger	106..126	CDD:275368	6/19 (32%)
		C2H2 Zn finger	134..155	CDD:275368	6/20 (30%)
		C2H2 Zn finger	188..210	CDD:275368	4/21 (19%)
		C2H2 Zn finger	217..237	CDD:275368	8/19 (42%)
		C2H2 Zn finger	253..276	CDD:275368	8/22 (36%)
		C2H2 Zn finger	283..302	CDD:275368	5/18 (28%)
Zfp65	XP_030103107.1	KRAB	15..72	CDD:214630	3/6 (50%)
		C2H2 Zn finger	93..113	CDD:275368	4/21 (19%)
		COG5048	116..>373	CDD:227381	75/284 (26%)
		C2H2 Zn finger	121..141	CDD:275368	1/19 (5%)
		C2H2 Zn finger	149..169	CDD:275368	7/21 (33%)
		C2H2 Zn finger	177..197	CDD:275368	7/22 (32%)
		C2H2 Zn finger	205..225	CDD:275368	6/20 (30%)
		C2H2 Zn finger	233..253	CDD:275368	4/19 (21%)
		C2H2 Zn finger	261..281	CDD:275368	4/21 (19%)
		C2H2 Zn finger	289..309	CDD:275368	8/19 (42%)
		C2H2 Zn finger	317..337	CDD:275368	8/22 (36%)
		C2H2 Zn finger	345..365	CDD:275368	6/21 (29%)
		C2H2 Zn finger	373..393	CDD:275368	5/19 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836466
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930