DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9609 and let-391

DIOPT Version :9

Sequence 1:	NP_573161.1	Gene:	CG9609 / 32663	FlyBaseID:	FBgn0030787	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_491744.3	Gene:	let-391 / 182953	WormBaseID:	WBGene00006492	Length:	453	Species:	Caenorhabditis elegans

Alignment Length:	287	Identity:	61/287 - (21%)
Similarity:	95/287 - (33%)	Gaps:	77/287 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 STHERPESAAKKTVKCALEECSKMFISVSNMTRHMRETHESPKVYPCSQCSAKFSQKLKLKRHEI 152
            ||:.:.:...|.......|.|.......|.:..||| ||...|.|.|..|..:|:|:..:..|..
Worm    42 STYRKKKGNQKLPTVTTCEVCGVALKYPSRIMEHMR-THTGEKPYECDICGMRFTQRTPMINHFR 105

  Fly   153 REHTLEYPYSCS-KCSRGFYQQWQCQSHEPS----------------CKLYECP----------- 189
            .:|..:.|:.|: .|.:.|....:..:||.|                .|...||
Worm   106 VQHMGDLPFLCNFGCGKRFVNNSRRTAHELSHNGLKRAGPARPYLKPVKKIVCPSMDMDILSNSA 170

  Fly   190 ----------------------GCPLQFDKWTLYTKHCRDSLHGKNRH---------KCD----- 218
                                  ..|.||......||   .|::...:.         :.|
Worm   171 LANYISPPTIDSIFQSDPSTSSSSPSQFQSSNQTTK---QSIYPSEKEMEKAAISNARIDDVINT 232

  Fly   219 ---RCDSAFDKPSELKRHLEVKHKEAAQTDECATSFTCNEEGCGKSYSYLRNLRQHMLTAHSGRR 280
               |..:..|:...::...:...|.|..::..||...||.  ||....:...:..|:.| |:|.:
Worm   233 VLARVLAPIDEEIPIEEPEKAPQKRAYISNRRATLAQCNI--CGLMLKHPSKIADHIRT-HTGEK 294

  Fly   281 -FECQALDCGRCFSSAQNLARHLLRDH 306
             |||.  :||...|.|.:|..|:.|.|
Worm   295 PFECG--ECGLSLSKASSLKVHIRRMH 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9609	NP_573161.1	C2H2 Zn finger	40..59	CDD:275368
		zf-C2H2_8	67..150	CDD:292531	17/61 (28%)
		C2H2 Zn finger	67..90	CDD:275368	1/1 (100%)
		C2H2 Zn finger	106..126	CDD:275368	6/19 (32%)
		C2H2 Zn finger	134..155	CDD:275368	5/20 (25%)
		C2H2 Zn finger	188..210	CDD:275368	8/54 (15%)
		C2H2 Zn finger	217..237	CDD:275368	3/27 (11%)
		C2H2 Zn finger	253..276	CDD:275368	6/22 (27%)
		C2H2 Zn finger	283..302	CDD:275368	6/18 (33%)
let-391	NP_491744.3	C2H2 Zn finger	59..79	CDD:275368	6/20 (30%)
		zf-H2C2_2	73..96	CDD:290200	10/23 (43%)
		C2H2 Zn finger	87..108	CDD:275368	5/20 (25%)
		C2H2 Zn finger	116..137	CDD:275368	5/20 (25%)
		C2H2 Zn finger	270..290	CDD:275368	6/22 (27%)
		zf-H2C2_2	286..304	CDD:290200	9/20 (45%)
		C2H2 Zn finger	298..319	CDD:275368	8/22 (36%)
		C2H2 Zn finger	327..347	CDD:275368
		C2H2 Zn finger	357..377	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100