DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9609 and gtf3ab

DIOPT Version :9

Sequence 1:	NP_573161.1	Gene:	CG9609 / 32663	FlyBaseID:	FBgn0030787	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_001083013.2	Gene:	gtf3ab / 100037394	ZFINID:	ZDB-GENE-030131-7698	Length:	318	Species:	Danio rerio

Alignment Length:	326	Identity:	98/326 - (30%)
Similarity:	151/326 - (46%)	Gaps:	31/326 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 GRRNSIGSAKYACSMPKCEATFKRLDQLDRHEYHHTGIKKHACSYEGCDKTYSIVTHLKRHLRST 89
            |.|....:..:.|:...|:|||.:|.:|:.|...|||:|..||.  .|:||:.....|.||..|
Zfish     2 GERIQDPNKHFTCTFADCKATFSKLWKLEVHYCRHTGLKPFACG--DCEKTFCTRYQLTRHQLS- 63

  Fly    90 HERPESAAKKTVKCALEECSKMFISVSNMTRHMRETHESPKV--YPCSQ--CSAKFSQKLKLKRH 150
                 .:.:|...|::..||..|.:..::..|:.:.|:: ||  |.|:.  |:.:|.:|.:||.|
Zfish    64 -----HSGEKPYLCSVSGCSAAFSTPGSLRNHIAQVHDN-KVRHYVCNYQGCAKEFHKKKQLKTH 122

  Fly   151 EIREHTLEYPYSC--SKCSRGFYQQWQCQSHEPSCKLYEC--PGCPLQFDKWTLYTKHCRDSLHG 211
             :.|||.|..:.|  .||:..|......:.|....:.|.|  ..|..:.:.|:.|.|| |.:.|.
Zfish   123 -LCEHTNELSFKCDHEKCNNKFASPKALKRHRKLHEGYPCGEENCNFKGNTWSEYLKH-RRTAHR 185

  Fly   212 KNRHKCDRCDSAFDKPSELKRHLEVKHKEAAQTDECATSFTCNEEGCGKSYSYLRNLRQHMLTAH 276
            .|. .|::|...|.|...|:.|.:..|....:      .|.|..|||.|||:...||..|:|..|
Zfish   186 VNL-PCNQCKKVFHKVCFLQMHKKFVHSGERR------MFKCTREGCQKSYTRRFNLENHVLDFH 243

  Fly   277 SGRR-FECQALDCGRCFSSAQNLARHLL----RDHKDGATKKELKAKKKDKSKTGEGGKTKSTSR 336
            .|:| |.|....|.:.|:..::|.||.:    :..|....|.:.|.||..|:||.:..|.....:
Zfish   244 EGKRDFTCHFTGCDKAFAMEESLKRHFVVHMPQKTKPQKPKVKPKRKKTSKAKTSDAAKLSEHLQ 308

  Fly   337 K 337
            |
Zfish   309 K 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9609	NP_573161.1	C2H2 Zn finger	40..59	CDD:275368	7/18 (39%)
		zf-C2H2_8	67..150	CDD:292531	24/86 (28%)
		C2H2 Zn finger	67..90	CDD:275368	8/22 (36%)
		C2H2 Zn finger	106..126	CDD:275368	4/19 (21%)
		C2H2 Zn finger	134..155	CDD:275368	7/22 (32%)
		C2H2 Zn finger	188..210	CDD:275368	7/23 (30%)
		C2H2 Zn finger	217..237	CDD:275368	6/19 (32%)
		C2H2 Zn finger	253..276	CDD:275368	11/22 (50%)
		C2H2 Zn finger	283..302	CDD:275368	5/18 (28%)
gtf3ab	NP_001083013.2	C2H2 Zn finger	18..36	CDD:275368	7/17 (41%)
		COG5048	40..>180	CDD:227381	43/150 (29%)
		C2H2 Zn finger	44..64	CDD:275368	8/27 (30%)
		C2H2 Zn finger	72..91	CDD:275368	4/18 (22%)
		C2H2 Zn finger	134..156	CDD:275368	5/21 (24%)
		C2H2 Zn finger	161..182	CDD:275368	7/21 (33%)
		C2H2 Zn finger	190..211	CDD:275368	6/20 (30%)
		C2H2 Zn finger	220..243	CDD:275368	11/22 (50%)
		C2H2 Zn finger	251..273	CDD:275368	6/21 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	141	1.000	Inparanoid score	I4465
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D500805at33208
OrthoFinder	1	1.000	-	-		FOG0004124
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	4.060