Protein Alignment if and Itga9

DIOPT Version :10

• Sequence 1: NP_523378.2
• Gene: if / 32661
• FlyBaseID: FBgn0001250
• Length: 1396
• Species: Drosophila melanogaster
• Sequence 2: NP_001406931.1
• Gene: Itga9 / 685004
• RGDID: 1311191
• Length: 1036
• Species: Rattus norvegicus
• Alignment Length: 920
• Identity: 250/920 - (27%)
• Similarity: 433/920 - (47%)
• Gaps: 148/920 - (16%)

  Fly    17 ITSLILLLIA--MSAHGYNIDLPSYVRFRQSSNSMFGFSIAMHKGRSGFYGNQNNVSLIVGAPKF 79
            :.:|:|.|:|  :.|..||||....|||:....|.||:::..|     |:.|...|  :|||||.
  Rat    14 LRALLLALVAAGVPAGAYNIDAQRPVRFQGPPGSFFGYAVLEH-----FHDNTRWV--LVGAPKA 71

  Fly    80 DTSRYQQGVTEAGGVFKCSLN-DDDCKLVPFD-SKGNNR--NVDKEVVDRKSYQWLGATVATGRD 140
            | |:|...|...|.||||.:: :.|.:....| ::..||  :..|.....:..:|:|.::|....
  Rat    72 D-SKYSTSVKSPGAVFKCRVHTNPDRRCTELDMARERNRGESCGKTCRGDRDDEWMGVSLARQPK 135

  Fly   141 SD-LVVACAPRY--VFHTMTPSRAFRIDPVGTCFTSHN------------FEEFYEVSPCRTNNW 190
            :| .|:|||.|:  :::     ....|.|.|.|:...:            :||:       ...:
  Rat   136 ADGRVLACAHRWKNIYY-----ETDHILPHGFCYLIPSNLQAKGRMLIPCYEEY-------KKKY 188

  Fly   191 GYHRQGSCQAGFSAAINGNGSRLFIGAPGSWYWQGQTYSIPPDAKFPFKPPLYQPFGTGGMASSH 255
            | ...||||||.:...  ....:.:|||||:||.| |..:
  Rat   189 G-EEHGSCQAGIAGFF--TEELVIMGAPGSFYWAG-TLKV------------------------- 224

  Fly   256 DVTRPENQVFSTSESASVNDD-SYLGYSMVTGDFDGDRSEDVAIGMPRGGNLVGRIVVNR----- 314
             :...:|..|..::.|.:|.. :||||::..|.|......||..|.|:... :|::.:.|
  Rat   225 -LNLTDNTYFKLNDDAIMNRRYTYLGYAVTAGHFSHPSVTDVVGGAPQDEG-IGKVYIFRADRRS 287

  Fly   315 WNMANIFNITGRQIGEYFGYSLATSDVDGDGLDDLLIGAPMYTDPDNVEGKYDVGRVYILL-QG- 377
            ..:..||..:|:::|.|||.||...|::.|||.|||:||||:::      ..|.|:|.:.| ||
  Rat   288 GTLIKIFQASGKKMGSYFGSSLCAVDLNMDGLSDLLVGAPMFSE------IRDEGQVTVYLNQGH 346

  Fly   378 GPTEEKRWTTEHIRDGYHSKGRFGLALTTLGDVNGDGYGDFAVGAPYDGPEGRGVVYIFHGSPMG 442
            |..||:...|.......|    ||.::.:|||::.||:.|.|||||.: .:..|.|||:||...|
  Rat   347 GVLEEQLTLTGDAAYNAH----FGESIASLGDLDDDGFPDVAVGAPME-DDFAGTVYIYHGDAQG 406

  Fly   443 PLAKPSQIIKSEQLVEGAPYPRTFGFALSGGLDMDGNTYPDLAVGAYSSDQVFIFKSRPVAAVNA 507
            .:.:.|..:...::   .|..:.||.::|||:|||||.|||:.|||:.||.|.:.::|||..|:.
  Rat   407 IVPQYSMKLSGRKI---NPILQMFGQSISGGIDMDGNGYPDVTVGAFLSDSVVLLRARPVITVDV 468

  Fly   508 ETSFASNSKLISLDDRSCQLVRDHKKVPCMLLTTCWSYTGRYLPEQLDFDVSWLLDA---KKLLN 569
             :.|...|  |::....|.  ...:.|.|:.:|.|:.:.|:.:|.::..:.:...|.   :|...
  Rat   469 -SIFLPGS--INITAPQCH--DGQQPVNCLNVTVCFRFHGKNVPGEIGLNYNLTADVAQKEKGQL 528

  Fly   570 PRMFF-LRDEGKNIRNQTIRLNYGQKYCLNETVYLLDKVQDKLTPLEVEARYNL---------RS 624
            ||::| |..|.....::.::|.:..:.|.:...::..:|||.::|:..||.|:|         |.
  Rat   529 PRVYFVLLGETAGQVSERLQLTHMDEVCHHYVAHVKRRVQDVISPIVFEAAYSLGEHVIGEEDRE 593

  Fly   625 SRPLDPMVRHRRSILEPVIDQNREIVLRDAINIQKNCGPDNICEPDL----KLKVSTVDK----Y 681
            ...|.|::|.::.  :.:..:|:.:       .::||..:: |..||    ||.:|:||:    .
  Rat   594 LPDLTPVLRWKKG--QRIAQKNQTV-------FERNCRSED-CAADLQLRGKLLLSSVDEKTTHL 648

  Fly   682 LFGSPEPLVIEVFISNTNEDAFEAAFYMVTPPDLQFRKLQQLGEKKDTPITCSPPTPENNHTLKC 746
            ..|:.:.:.:.:.|||..:||::|........:|.|..:.|   |::..|:|.  ..|::. |||
  Rat   649 ALGAVKNISLNISISNLGDDAYDANVSFNVSRELFFINMWQ---KEEMGISCE--LLESDF-LKC 707

  Fly   747 DIGNPLESGKIAHFKISLVPEEKY--GSSSSYDFYWEANSTNLEKPGSEYDNKIRQSVGIWVDTD 809
            .:|.|....| :.::.|::.:..:  |......|...|.|.|:|:..:.:||.:..::.:..:.|
  Rat   708 SVGFPFMRSK-SKYEFSVIFDTSHLSGEEEILSFIVTAQSGNMERSEALHDNTLTLTIPLVHEVD 771

  Fly   810 LDIKGTSLPDYQLY----KADDYKELENATKEDDIGPQVVHI-YEIRNNRPSIIEEAEVFIHLPY 869
            ..|.|...|...:|    .|.::.:|:    :.:...|.|:| .::.|..||.:..:.|.|..|.
  Rat   772 TSITGIVSPTSFVYGESVDASNFIQLD----DQECHFQPVNITLQVYNMGPSTLPGSSVSISFPS 832

  Fly   870 ETIVGDPLMY 879
            ....|...|:
  Rat   833 RLSPGGAEMF 842

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
if	NP_523378.2	Int_alpha	46..110	CDD:214549	22/64 (34%)
		Int_alpha	275..>316	CDD:214549	12/46 (26%)
		Int_alpha	398..451	CDD:214549	21/52 (40%)
		Int_alpha	466..>497	CDD:214549	19/30 (63%)
		Integrin_alpha2	500..892	CDD:462478	93/408 (23%)
		Glutenin_hmw	<1121..1216	CDD:367362
Itga9	NP_001406931.1	Int_alpha	45..102	CDD:214549	22/64 (34%)
		Int_alpha	245..295	CDD:214549	13/50 (26%)
		Int_alpha	301..347	CDD:214549	23/51 (45%)
		Int_alpha	362..415	CDD:214549	22/57 (39%)
		Int_alpha	425..>467	CDD:214549	22/41 (54%)
		Integrin_alpha2	461..904	CDD:462478	93/408 (23%)