Protein Alignment if and itga6l

DIOPT Version :10

• Sequence 1: NP_523378.2
• Gene: if / 32661
• FlyBaseID: FBgn0001250
• Length: 1396
• Species: Drosophila melanogaster
• Sequence 2: XP_021336955.3
• Gene: itga6l / 555254
• ZFINID: ZDB-GENE-040914-57
• Length: 1035
• Species: Danio rerio
• Alignment Length: 958
• Identity: 276/958 - (28%)
• Similarity: 440/958 - (45%)
• Gaps: 164/958 - (17%)

  Fly    32 YNIDLPSYVRFRQSSNSMFGFSIAMHKGRSGFYGNQNNVS----LIVGAPKFDTSRYQQGVTEAG 92
            :|:|..:.:|.|..::|:||||:|||        :|...|    |::|||:...... |....:|
Zfish    22 FNLDTQNVMRKRGEADSLFGFSMAMH--------HQLKPSDQRVLLIGAPRAKALPV-QNANISG 77

  Fly    93 GVFKC--SLNDDDCKLVPFDSKGNNRNVDKEVVDRKSYQWLGATVATGRDSDLVVACAPRYVFHT 155
            |:::|  :...|||:.:|.|.|.  |:.|...||.:..||||.:|.:......||.||.||...:
Zfish    78 GLYRCKFTTQPDDCERIPVDIKA--RSKDHPGVDYRENQWLGVSVQSQGRGGKVVTCAHRYQDWS 140

  Fly   156 MTPSRAFRIDPVGTCFT-------------SHNFEEFYEVSPCRTNNWGYHRQGSCQAGFSAAIN 207
            .|..|.     :|.||.             :.:|        |||.....|..|.||.|.|.|.:
Zfish   141 FTNQRL-----LGRCFVLGQDLVLGTDGADTRSF--------CRTRETDKHNFGYCQQGLSVAFS 192

  Fly   208 GNGSRLFIGAPGSWYWQGQTYSIPPDAKFPFKPPLYQPFGTGGMASSHDVTRPENQVFSTSESAS 272
            .:...|..||||::.|:|..:..|.:   .|...:|:      .|..|::.             .
Zfish   193 KDSKYLVYGAPGAYDWKGIVHMEPVE---DFSLEIYE------TADEHELN-------------P 235

  Fly   273 VNDDSYLGYSMVTGDFDGDRSE-DVAIGMPRGGNLVGRIVV----NRWNMANI---FNITGRQIG 329
            |:..|:||:::.||.....:.| :|..|.|| .|..|.:::    :|....|:   ..:.|..:.
Zfish   236 VDISSFLGFALDTGMNLMKKGELNVVAGAPR-SNHSGEVLLLRPEDRTEARNLQVEHILRGPGLA 299

  Fly   330 EYFGYSLATSDVDGDGLDDLLIGAPMYTDPDNVEGKYDV-GRVYILLQGGPTEEKRWTTEHIRDG 393
            ..|||.|...|::.||.||:::|||.::. .|::.  || |.|||.:  ...|.:.|:  |.:..
Zfish   300 SSFGYDLTILDLNADGWDDIVVGAPEFSS-KNMDD--DVGGAVYIYI--NQAEGQHWS--HFQPV 357

  Fly   394 --YHSK-GRFGLALTTLGDVNGDGYGDFAVGAPYDGPEGRGVVYIFHGSPMGPLAKPSQIIKSEQ 455
              |..| ..||||:..:||:|.|||.|||..||.: ..|||.|||:|||..|...||:.:...:.
Zfish   358 CLYGKKDSMFGLAVAHVGDLNQDGYQDFAASAPNE-DSGRGRVYIYHGSAAGFHHKPTILDAGDH 421

  Fly   456 LVEGAPYPRTFGFALSGGLDMDGNTYPDLAVGAYSSDQVFIFKSRPVAAVNAETSFASNSKLISL 520
            .:      :.||::|:|.:|||||.||:||||:: ||.|.|::::||  :|.|.:.......|..
Zfish   422 SI------KLFGYSLAGNMDMDGNGYPELAVGSF-SDTVLIYRTKPV--INIEKTLTLTPNKIDF 477

  Fly   521 DDRSCQLVRDHKKVPCMLLT-TCWSYTGR---YLPEQLDFDVSWLLDA-----KKLLNPRMFFLR 576
            ..:.|      |:.||::.. :|::||..   |.|:   ..:.:.|:|     ::.|..|:.|:.
Zfish   478 KAQDC------KRKPCIITAQSCFTYTTEPQTYNPK---LRIEYKLEADTVRRERGLPSRVVFVN 533

  Fly   577 DEGKNIRNQTIRLNYGQKYCLNETVYLLDKVQDKLTPLEVEARYNLRSSRPLDPMVRHRRSI--L 639
            .:..|.|.|.....  ||.|:...:.||.::|||||.:.:....:|.|..|...:    |::  |
Zfish   534 SDAANGRQQLKAQR--QKSCVQTKLRLLGEIQDKLTSISISLSVSLPSDNPKQTI----RNLPDL 592

  Fly   640 EPVIDQNREIVLRDAIN-IQKNCGPDNICEPDLKLKVS---------TVDKYLFGSPEPLV---- 690
            |||::..:|...:..:: :...||.||||:.:|:|:.|         ..|.....:..|::
Zfish   593 EPVLNTLQEKTSKAEVSFLNSGCGSDNICQSNLQLQYSFCTKDQQQDQCDPLAMENGVPVISPGD 657

  Fly   691 ----IEVFISNT-NEDAFEAAFYMVTPPDLQFRKLQQLGEKKD--TPITCSPPTPENNHTLKCDI 748
                :||.::|| .:||.....|::.|..|.   |..:..||:  |.:.|:|  .||.....|.:
Zfish   658 VNIALEVTVTNTGGDDAHHTQLYVMFPEVLH---LTSVVPKKNSVTQVQCNP--NENRTQADCQL 717

  Fly   749 GNPLESGKIAHFKISLVPEEKYGSSSSYDFYWEANSTNLEKPGSEYDNKI-RQSVGIWVDTDLDI 812
            ||||:......|.:.|..|:.....:|      ||.|...|..|..|..| .....|..:..|:|
Zfish   718 GNPLKRDAEVSFFLMLNTEKLSLRVTS------ANVTLALKTISIQDVPIVVAEAKIIFELHLNI 776

  Fly   813 KGTSLPDYQLYKADDYKELENATKEDDIGPQVVHIYEIRN-NRP-SIIEEAEVFIHLPYETIVGD 875
            .|.:.|. ||:...:.|:.:....|||:|..|.:.:.|.| .|| .....|.:.|..|..|..|.
Zfish   777 IGLAKPS-QLFFGGEVKDEKAMKAEDDVGSLVQYEFRIFNIGRPLKSFGSAVLNIQWPKATKAGK 840

  Fly   876 PLMYLLNQPETGGK-IQC------DDVAFNEYNLLLDEKLVKKSYLQA 916
            .|:||:...:.|.. |.|      :.:.||..:.....:|.::|.|:|
Zfish   841 RLLYLMQITDRGKNIIHCTPSEAINTLRFNMASSRGKRELERESGLKA 888

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
if	NP_523378.2	Int_alpha	46..110	CDD:214549	22/69 (32%)
		Int_alpha	275..>316	CDD:214549	13/45 (29%)
		Int_alpha	398..451	CDD:214549	27/52 (52%)
		Int_alpha	466..>497	CDD:214549	18/30 (60%)
		Integrin_alpha2	500..892	CDD:462478	112/427 (26%)
		Glutenin_hmw	<1121..1216	CDD:367362
itga6l	XP_021336955.3	None