Protein Alignment if and itga11a

DIOPT Version :9

• Sequence 1: NP_001162777.1
• Gene: if / 32661
• FlyBaseID: FBgn0001250
• Length: 1396
• Species: Drosophila melanogaster
• Sequence 2: NP_001166098.1
• Gene: itga11a / 541475
• ZFINID: ZDB-GENE-050324-1
• Length: 1190
• Species: Danio rerio
• Alignment Length: 1052
• Identity: 237/1052 - (22%)
• Similarity: 403/1052 - (38%)
• Gaps: 272/1052 - (25%)

  Fly    44 QSSNSMFGFSIAMHKG--RSGFYGNQNNVSLIVGAPKFDTSRYQQGVTEAGGVFKCSLNDDDCKL 106
            :.:|:..|.::|..:.  :.|..|.:..:.:|......|::..||.:.|:
Zfish   242 EETNTALGINVARSEAFKQGGRRGAKKVMIVITDGESHDSADLQQVIEES--------------- 291

  Fly   107 VPFDSKGNNRNVDKEVVDRKSYQWLGATVATGRDSDLVVACAPRYV--------FHTMTPSRAFR 163
                        :|:.:.|.:...||.....|.:.:..:. ..:|:        |..:|...|.:
Zfish   292 ------------EKDGITRYAIAVLGYYNRRGINPEAFLN-EIKYIASDPDDKHFFNVTDEAALK 343

  Fly   164 --IDPVGTCFTSHNFEEFYEVSPCRTNNWGYHRQGSCQAGFSAAINGNGSRLFIGAPGSWYWQG- 225
              :|.:|        |..:.:.....|...:..|.| |||||.....:|  :.:||.|::.|.|
Zfish   344 DIVDALG--------ERIFSLEGTSKNGTAFGLQMS-QAGFSTHTVEDG--ILVGAVGAYDWNGA 397

  Fly   226 ------QTYSIPPDAKFPFKPPLYQPFGTGGMASSHDVTRPENQVFSTSESASVNDDSYLGYSMV 284
                  |...:||                   .||::...||.         ..|..:||||: |
Zfish   398 VLKETRQGKVVPP-------------------KSSYEQEFPEE---------LKNHGAYLGYT-V 433

  Fly   285 TGDFDGDRSEDVAIGMPRGGNLVGRIVV----NRWNMANIFNITGRQIGEYFGYSLATSDVDGDG 345
            |........:....|.|| .|..|::::    |...:..:.::.|:|||.|:|..:|..|:|.||
Zfish   434 TSVVSARSGQLYVAGAPR-FNHTGKVIIFTLKNTGELTILHSLKGQQIGSYYGSEIAPVDIDNDG 497

  Fly   346 L-DDLLIGAPMYTDPDNVEGKYDVGRVYILLQGGPTEEKRW----TTEHIRDGYHSKGRFGLALT 405
            : |:||:.|||:     ..|.::.|:|||.   ..||:.|:    :.|.:..|.::  |||.||.
Zfish   498 VTDNLLVAAPMF-----FSGGWEKGKVYIY---RVTEQPRFILEGSLEVLDQGQNA--RFGSALA 552

  Fly   406 TLGDVNGDGYGDFAVGAPYDGPEGRGVVYIFHGSPMGPLAKPSQIIKSEQLVEGAPYPRTFGFAL 470
            .:.|:|||.:.|..||||.: .:.:|.:||:|......|.|..|.|.:.||..|..|   ||.::
Zfish   553 PVPDLNGDSFNDVVVGAPLE-DDHKGAIYIYHSQRNRILRKYKQRIGAVQLGPGLQY---FGRSI 613

  Fly   471 SGGLDMDGNTYPDLAVGAYSSDQVFIFKSRPVAAVNAETSFASNSKLISLDDRSCQLVRDHKKVP 535
            .|.:||:|:...|||||:..:  ..:..||.|..:|:...|..:.  |::.::.|:  |..|.|.
Zfish   614 HGKMDMNGDDLVDLAVGSLGA--AVLLWSRSVIRINSVVRFEPSK--INIFNKDCR--RGGKDVT 672

  Fly   536 CMLLTTCWSYTGRYLPEQLDFDVSWLLDA---KKLLNPRMFFLRDEGKNIRNQTIRLNYGQKYCL 597
            ||....|.:.|.| .|.....:::....|   :|..|||..|  |:....:.|.:.|..|::.|
Zfish   673 CMSAIVCLNVTAR-TPINPSQEIALRYSAFFEEKRFNPRAVF--DDPDRQQPQNLTLLPGEETC- 733

  Fly   598 NETVYL-LDKVQDKLTPLEVEARYNLRSSRPLDPMVRHRRSILEPVIDQNREIVLRDAINIQKNC 661
             :.:|. :.:..|...|:.......|     ||  :.|     .||:|.:....::..:.....|
Zfish   734 -DHIYFHVMETTDYARPIIFTVETEL-----LD--LYH-----GPVLDDSWPTTVKTQLPFWNGC 785

  Fly   662 GPDNICEPDLKLKVST----------------------------VDKYLFGSPEPLVIEVFISNT 698
            ..|:.|.|||.|:..|                            .::.:.||...:|::|.:.|.
Zfish   786 DEDDHCVPDLLLQAHTDLMNRQQFCGQAFRAASLLCQGHTSTDPSERIIEGSRRKMVVDVRLENR 850

  Fly   699 NEDAFEAAFYMVTPPDLQFRKLQQLGEKKDTPITCSPPTPENNHTLK--CDIGNPLESGK----- 756
            .|:|:.|...:....:|:|..| .:.:..|..|.|   ..||....:  |:|..|....|
Zfish   851 GENAYGAKLNITYTQNLRFSSL-IVKDNSDIHIDC---RNENKRKYEKTCNISEPFMRAKSQVIF 911

  Fly   757 -----------IAHFKISLVPEEKYGSSSSYDFYWEANSTNLEKPGSE---YDNKIRQSVGIWVD 807
                       :.|.:|.|                     .:...|.|   |||.......:..:
Zfish   912 RLEFEFSHSVLLDHVRIIL---------------------EVTSEGEEVILYDNSNEIFYNLKYE 955

  Fly   808 TDL-----------DIKGTSLPDYQLYKADDYKELENATKEDDIGPQVVHIYEIRNNRPSIIEEA 861
            .||           ::|    ||..|.||||:....|.|            ::|:|.....|::.
Zfish   956 ADLLFTRDFYPTRYELK----PDLSLEKADDFNPPFNFT------------FQIQNLGYFPIQDL 1004

  Fly   862 EVFIHLPYETIVGDPLMYL--LNQPETGGKIQCDDVAFNEYNLLLDEKLVKKSYLQAQGAIWNSA 924
            :::|.:|..|..|:.|:.:  .:..:.||. ||.......::....|.|.:.|.|.....:....
Zfish  1005 QLYIAIPEVTKNGNQLLQIRDFHIDQIGGS-QCIPPQHVAHSRASPEDLSRTSRLNYSNTLAVPV 1068

  Fly   925 QVSGQSSS----SSSSGGA----SVHIEKARGEGFVRGVLVSNSTDAGDKLSPKQ---------- 971
            |.:....|    |...||:    ::|..|.:....|        |.|..:|:|..
Zfish  1069 QCTVNLPSYRDVSVKIGGSLRTDALHALKFKTLELV--------TTASVELNPSSPMFLPEERPV 1125

  Fly   972 ----VEQRRQED 979
                :|.|::||
Zfish  1126 RHIILEIRKEED 1137

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
if	NP_001162777.1	Int_alpha	46..110	CDD:214549	10/65 (15%)
		Int_alpha	275..>316	CDD:214549	12/44 (27%)
		Int_alpha	398..451	CDD:214549	21/52 (40%)
		Int_alpha	466..>497	CDD:214549	11/30 (37%)
		Integrin_alpha2	499..893	CDD:285619	96/459 (21%)
		DUF2756	<1120..1178	CDD:298627
itga11a	NP_001166098.1	Int_alpha	39..88	CDD:214549
		vWA_integrins_alpha_subunit	167..345	CDD:238746	19/130 (15%)
		Int_alpha	480..527	CDD:214549	21/54 (39%)
		Int_alpha	543..587	CDD:214549	18/46 (39%)
		VCBS	556..629	CDD:290251	29/76 (38%)
		Integrin_alpha2	640..1042	CDD:285619	97/464 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574974
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3637
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740