Protein Alignment if and itga11a

DIOPT Version :10

• Sequence 1: NP_523378.2
• Gene: if / 32661
• FlyBaseID: FBgn0001250
• Length: 1396
• Species: Drosophila melanogaster
• Sequence 2: NP_001166098.2
• Gene: itga11a / 541475
• ZFINID: ZDB-GENE-050324-1
• Length: 1190
• Species: Danio rerio
• Alignment Length: 1036
• Identity: 241/1036 - (23%)
• Similarity: 406/1036 - (39%)
• Gaps: 240/1036 - (23%)

  Fly    44 QSSNSMFGFSIAMHKG--RSGFYGNQNNVSLIVGAPKFDTSRYQQGVTEAGGVFKCSLNDDDCKL 106
            :.:|:..|.::|..:.  :.|..|.:..:.:|......|::..||.:.|:
Zfish   242 EETNTALGINVARSEAFKQGGRRGAKKVMIVITDGESHDSADLQQVIEES--------------- 291

  Fly   107 VPFDSKGNNRNVDKEVVDRKSYQWLGATVATGRDSDLVVACAPRYV--------FHTMTPSRAFR 163
                        :|:.:.|.:...||.....|.:.:..:. ..:|:        |..:|...|.:
Zfish   292 ------------EKDGITRYAIAVLGYYNRRGINPEAFLN-EIKYIASDPDDKHFFNVTDEAALK 343

  Fly   164 --IDPVGTCFTSHNFEEFYEVSPCRTNNWGYHRQGSCQAGFSAAINGNGSRLFIGAPGSWYWQG- 225
              :|.:|        |..:.:.....|...:..|.| |||||.....:|  :.:||.|::.|.|
Zfish   344 DIVDALG--------ERIFSLEGTSKNGTAFGLQMS-QAGFSTHTVEDG--ILVGAVGAYDWNGA 397

  Fly   226 ------QTYSIPPDAKFPFKPPLYQPFGTGGMASSHDVTRPENQVFSTSESASVNDDSYLGYSMV 284
                  |...:||                   .||::...||.         ..|..:||||: |
Zfish   398 VLKETRQGKVVPP-------------------KSSYEQEFPEE---------LKNHGAYLGYT-V 433

  Fly   285 TGDFDGDRSEDVAIGMPRGGNLVGRIVV----NRWNMANIFNITGRQIGEYFGYSLATSDVDGDG 345
            |........:....|.|| .|..|::::    |...:..:.::.|:|||.|:|..:|..|:|.||
Zfish   434 TSVVSARSGQLYVAGAPR-FNHTGKVIIFTLKNTGELTILHSLKGQQIGSYYGSEIAPVDIDNDG 497

  Fly   346 L-DDLLIGAPMYTDPDNVEGKYDVGRVYILLQGGPTEEKRW----TTEHIRDGYHSKGRFGLALT 405
            : |:||:.|||:     ..|.::.|:|||.   ..||:.|:    :.|.:..|.::  |||.||.
Zfish   498 VTDNLLVAAPMF-----FSGGWEKGKVYIY---RVTEQPRFILEGSLEVLDQGQNA--RFGSALA 552

  Fly   406 TLGDVNGDGYGDFAVGAPYDGPEGRGVVYIFHGSPMGPLAKPSQIIKSEQLVEGAPYPRTFGFAL 470
            .:.|:|||.:.|..||||.: .:.:|.:||:|......|.|..|.|.:.||..|..|   ||.::
Zfish   553 PVPDLNGDSFNDVVVGAPLE-DDHKGAIYIYHSQRNRILRKYKQRIGAVQLGPGLQY---FGRSI 613

  Fly   471 SGGLDMDGNTYPDLAVGAYSSDQVFIFKSRPVAAVNAETSFASNSKLISLDDRSCQLVRDHKKVP 535
            .|.:||:|:...|||||:..:  ..:..||.|..:|:...|..:.  |::.::.|:  |..|.|.
Zfish   614 HGKMDMNGDDLVDLAVGSLGA--AVLLWSRSVIRINSVVRFEPSK--INIFNKDCR--RGGKDVT 672

  Fly   536 CMLLTTCWSYTGRYLPEQLDFDVSWLLDA---KKLLNPRMFFLRDEGKNIRNQTIRLNYGQKYCL 597
            ||....|.:.|.| .|.....:::....|   :|..|||..|  |:....:.|.:.|..|::.|
Zfish   673 CMSAIVCLNVTSR-TPINPSQEIALRYSAFFEEKRFNPRAVF--DDPDRQQPQNLTLLPGEETC- 733

  Fly   598 NETVYL-LDKVQDKLTPLEVEARYNLRSSRPLDPMVRHRRSILEPVIDQNREIVLRDAINIQKNC 661
             :.:|. :.:..|...|:.......|     ||  :.|     .||:|.:....::..:.....|
Zfish   734 -DHIYFHVMETTDYARPIIFTVETEL-----LD--LYH-----GPVLDDSWPTTVKTQLPFWNGC 785

  Fly   662 GPDNICEPDLKLKVST----------------------------VDKYLFGSPEPLVIEVFISNT 698
            ..|:.|.|||.|:..|                            .::.:.||...:|::|.:.|.
Zfish   786 DEDDHCVPDLLLQAHTDLMNRQQFCGQAFRAASLLCQGHTSTDPSERIIEGSRRKMVVDVRLENR 850

  Fly   699 NEDAFEAAFYMVTPPDLQFRKLQQLGEKKDTPITCSPPTPENNHTLK--CDIGNPLESGKI-AHF 760
            .|:|:.|...:....:|:|..| .:.:..|..|.|   ..||....:  |:|..|....|. ..|
Zfish   851 GENAYGAKLNITYTQNLRFSSL-IVKDNSDIHIDC---RNENKRKYEKTCNISEPFMRAKSQVIF 911

  Fly   761 KISLVPEEKYGSSSSYD---FYWEANSTNLEKPGSE---YDNKIRQSVGIWVDTDL----DIKGT 815
            ::    |.::..|...|   ...|..|     .|.|   |||.......:..:.||    |...|
Zfish   912 RL----EFEFSHSELLDHVRIILEVTS-----EGEEVILYDNSNEIFYNLKYEADLLFTRDFYPT 967

  Fly   816 SL---PDYQLYKADDYKELENATKEDDIGPQVVHIYEIRNNRPSIIEEAEVFIHLPYETIVGDPL 877
            ..   ||..|.||||:....|.|            ::|:|.....|::.:::|.:|..|..|:.|
Zfish   968 RYELKPDLSLEKADDFNPPFNFT------------FQIQNLGYFPIQDLQLYIAIPEVTKNGNQL 1020

  Fly   878 MYL--LNQPETGGKIQCDDVAFNEYNLLLDEKLVKKSYLQAQGAIWNSAQVSGQSSS----SSSS 936
            :.:  .:..:.||. ||.......::....|.|.:.|.|.....:....|.:....|    |...
Zfish  1021 LQIRDFHIDQIGGS-QCIPPQHVAHSRASPEDLSRTSRLNYSNTLAVPVQCTVNLPSYRDVSVKI 1084

  Fly   937 GGA----SVHIEKARGEGFVRGVLVSNSTDAGDKLSPKQ--------------VEQRRQED 979
            ||:    ::|..|.:....|        |.|..:|:|..              :|.|::||
Zfish  1085 GGSLRTDALHALKFKTLELV--------TTASVELNPSSPMFLPEERPVRHIILEIRKEED 1137

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
if	NP_523378.2	Int_alpha	46..110	CDD:214549	10/65 (15%)
		Int_alpha	275..>316	CDD:214549	12/44 (27%)
		Int_alpha	398..451	CDD:214549	21/52 (40%)
		Int_alpha	466..>497	CDD:214549	11/30 (37%)
		Integrin_alpha2	500..892	CDD:462478	98/441 (22%)
		Glutenin_hmw	<1121..1216	CDD:367362
itga11a	NP_001166098.2	None