Protein Alignment if and Gpld1

DIOPT Version :9

• Sequence 1: NP_001162777.1
• Gene: if / 32661
• FlyBaseID: FBgn0001250
• Length: 1396
• Species: Drosophila melanogaster
• Sequence 2: NP_001093982.1
• Gene: Gpld1 / 291132
• RGDID: 631371
• Length: 843
• Species: Rattus norvegicus
• Alignment Length: 409
• Identity: 100/409 - (24%)
• Similarity: 151/409 - (36%)
• Gaps: 134/409 - (32%)

  Fly   227 TYSIPPDAKFPFKPPLYQPFGTGGM-------------------ASSHDVTRPENQVFSTSESAS 272
            |||    .|.||....:|.:..||:                   ..:.|...|||.:|.:.:.
  Rat   231 TYS----TKSPFLVEQFQDYFLGGLDDMAFWSTNIYRLTSFMLENGTSDCNLPENPLFISCDG-- 289

  Fly   273 VNDDSYLGYSMV-TGDFDGDRSEDVAIGMPRGGNLVGRIV---VNRW--------------NMAN 319
             ..:..|..|.| ..||..:.:..::..:.:..|...|.|   ...|              |:..
  Rat   290 -RKNHTLSSSKVQKNDFHRNLTMFISKDIRKNLNYTERGVFYSTGSWAPESVTFMYQTLERNLRM 353

  Fly   320 IFNITGRQ----------IGEY--------FGYSLATSDVDGDGLDDLLIGAPMYTDPDNVEGKY 366
            :|  ||..          ...|        .|:.:|::|::.||..||::|||.|:.|    |::
  Rat   354 MF--TGNSQTALKHVSSPSASYTLSVPYARLGWVMASADLNQDGHGDLVVGAPGYSHP----GRF 412

  Fly   367 DVGRVYILL---QGGPTEEKRWTTE-H-IRDGYHSKGRFGLALTTLGDVNGDGYGDFAVGAPYDG 426
            .:|||||:.   .|.|..:.....| | :.:|:...||||.||..| |.|.||..|.|||||..|
  Rat   413 QIGRVYIIYGNDLGLPPIDLDLDKEAHGVLEGFQPSGRFGSALAVL-DFNKDGLPDLAVGAPSVG 476

  Fly   427 PEGR----GVVYIFHGSPMGPL-AKPSQIIKSEQLVEGAPYPRTF---GFALSGGLDMDGNTYPD 483
             .|:    |.||:::||..|.| :.|:..|..:.         |:   |:||... |.||:...|
  Rat   477 -SGQLTYNGSVYVYYGSQQGRLSSSPNITISCKD---------TYCNLGWALLAA-DADGDGQHD 530

  Fly   484 LAV-------GAYSSDQVFIFKSRPVAAVNAETSFASNSKLISLDDRSCQLVRDHKKVPCMLLTT 541
            |.:       |......|..|.|.|         ..::.:.::||:..
  Rat   531 LVISSPFAPGGGKQRGIVAAFYSHP---------RRNDKESLTLDEAD----------------- 569

  Fly   542 CWSYTGRYLPEQLDFDVSW 560
             |...|       :.|.||
  Rat   570 -WKVNG-------EEDFSW 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
if	NP_001162777.1	Int_alpha	46..110	CDD:214549
		Int_alpha	275..>316	CDD:214549	9/58 (16%)
		Int_alpha	398..451	CDD:214549	27/57 (47%)
		Int_alpha	466..>497	CDD:214549	10/40 (25%)
		Integrin_alpha2	499..893	CDD:285619	9/62 (15%)
		DUF2756	<1120..1178	CDD:298627
Gpld1	NP_001093982.1	Zn_dep_PLPC	28..220	CDD:395710
		FG-GAP 1. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	368..429		20/64 (31%)
		Int_alpha	378..435	CDD:214549	20/60 (33%)
		FG-GAP 2. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	435..498		28/64 (44%)
		Int_alpha	447..503	CDD:214549	27/57 (47%)
		FG-GAP 3. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	500..560		16/78 (21%)
		FG-GAP	515..548	CDD:396418	9/33 (27%)
		FG-GAP 4. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	564..625		7/42 (17%)
		FG-GAP 5. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	635..695
		FG-GAP 6. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	707..773
		FG-GAP 7. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	791..843

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3637
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D743479at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910