Protein Alignment if and itgae

DIOPT Version :9

• Sequence 1: NP_001162777.1
• Gene: if / 32661
• FlyBaseID: FBgn0001250
• Length: 1396
• Species: Drosophila melanogaster
• Sequence 2: XP_031752522.1
• Gene: itgae / 105946656
• XenbaseID: XB-GENE-1013152
• Length: 1170
• Species: Xenopus tropicalis
• Alignment Length: 607
• Identity: 165/607 - (27%)
• Similarity: 264/607 - (43%)
• Gaps: 125/607 - (20%)

  Fly   199 QAGFSAAINGNGSRLFIGAPGSWYWQGQTYSIPPDAKFPFKPPLYQPFGTGGMASSHDVTRPENQ 263
            :|||:..:..|.| :.:|..|::.|                        :||:......|:|...
 Frog   409 EAGFAVHLKNNES-MILGTAGAFDW------------------------SGGLMLYQMNTQPHKI 448

  Fly   264 VF--STSESASVNDDSYLGYSMVTGDFDGDRSEDVAIGMPRGGNLVGRIV-----VNRWNMANIF 321
            .|  .|.|..:....|||||| ||.......|..:| |.||..| ||:::     :..:.:|.
 Frog   449 TFLNETKEKTAEASYSYLGYS-VTAAQRQHTSLYIA-GAPRHSN-VGKVLIFEEDIRTYRLAQ-- 508

  Fly   322 NITGRQIGEYFGYSLATSDVDGDGLDDLL-IGAPMYTDPDNVEGKYDVGRVYILLQGGPTEEKRW 385
            .:||.|||.|||..|.:.|:|.|...||| :|||.|    :::|  :.||||:.........|.:
 Frog   509 ELTGEQIGSYFGSELCSVDIDMDSNTDLLMVGAPFY----HIKG--EEGRVYVYRLNDEGHHKFF 567

  Fly   386 TTEHIRDGYHSKGRFGLALTTLGDVNGDGYGDFAVGAPYDG----PEGRGVVYIFHGSPMGPLAK 446
            .|  :....:...|||.::..:||:|.|||.|.|:|||.:|    ||..|.|||::|........
 Frog   568 ET--LEQPQYPFARFGYSIANVGDINKDGYRDIAIGAPLEGHLENPESFGSVYIYNGESNSIRTT 630

  Fly   447 PSQIIKSEQLVEGAPYPRTFGFALSGGLDMDGNTYPDLAVGAYSSDQVFIFKSRPVAAVNAETSF 511
            |||.|::..:.:...|...||.::.||||:..:.|||:|||  |...:.|.:||||  :..:.|.
 Frog   631 PSQRIRASTIKKAPHYCPYFGLSVDGGLDLTNDGYPDVAVG--SLGNLIILRSRPV--IKLQASV 691

  Fly   512 ASNSKLI-------SLDDRSCQLVRDHKKVPCMLLTTCWSYTGRYLPEQLDFDVSWLLDAKKLLN 569
            ....|:|       ||..|.|..:...|  |...|.:       :|...:|.||       ::..
 Frog   692 DLTPKVIPVINGNTSLTARLCFTITPFK--PQEFLKS-------HLHYAVDLDV-------EMKQ 740

  Fly   570 PRMFFLRDEGKNIRNQTIRLNYGQKYCLN----ETVYLLDKVQDKLTPLEVEARYNLRSSRPLDP 630
            .|:.|.:.:..|          |:.:.:|    :.|..:....|..|.::::..|.|.|..
 Frog   741 KRIEFRKGDSGN----------GKLFLVNVKCSDLVLTVLPCTDCFTSIKIKVSYTLVSDL---- 791

  Fly   631 MVRHRRSILEPVIDQNREIVLRDAIN-------IQKNCGPDNICEPDLKLKVS-TVDKYLFGSPE 687
                .|.:..|::|     |..:|.|       .:|:|....:|.|:|.|... :.::.:.|...
 Frog   792 ----NRDLPAPILD-----VYDNAHNHTYFEIPYEKDCNNKPVCVPELHLTTRLSGNELIVGYTR 847

  Fly   688 PLVIEVFISNTNEDAFEAAFYMVTPPDLQFRKLQQLGEKKDTP----ITCSPP--TPENNHTLKC 746
            .|::.:.:.|:.:.::.....::.|..|||:.::       ||    :.||||  .|..:..:.|
 Frog   848 DLIMNISLVNSGDGSYLTTMMVIYPKSLQFKLVK-------TPAFPVVKCSPPEMLPTFSSVMSC 905

  Fly   747 DIGNPLESGKIAHFKISLVPEE 768
            .||.|:.|...|.|.|.|..||
 Frog   906 SIGYPVFSKSSAEFSIILQLEE 927

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
if	NP_001162777.1	Int_alpha	46..110	CDD:214549
		Int_alpha	275..>316	CDD:214549	16/45 (36%)
		Int_alpha	398..451	CDD:214549	25/56 (45%)
		Int_alpha	466..>497	CDD:214549	13/30 (43%)
		Integrin_alpha2	499..893	CDD:285619	66/295 (22%)
		DUF2756	<1120..1178	CDD:298627
itgae	XP_031752522.1	vWFA	208..384	CDD:412136
		Int_alpha	515..562	CDD:214549	21/52 (40%)
		Int_alpha	576..635	CDD:214549	25/58 (43%)
		Int_alpha	649..>672	CDD:214549	12/24 (50%)
		Integrin_alpha2	681..1064	CDD:400650	66/295 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D743479at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010