Protein Alignment if and itga1

DIOPT Version :9

• Sequence 1: NP_001162777.1
• Gene: if / 32661
• FlyBaseID: FBgn0001250
• Length: 1396
• Species: Drosophila melanogaster
• Sequence 2: XP_002933090.3
• Gene: itga1 / 100492880
• XenbaseID: XB-GENE-6258629
• Length: 1173
• Species: Xenopus tropicalis
• Alignment Length: 1112
• Identity: 231/1112 - (20%)
• Similarity: 398/1112 - (35%)
• Gaps: 354/1112 - (31%)

  Fly    17 ITSLILLLIAMSAHGYNIDLPSYVRFRQSSNSMFGFSIAMHKGRSGFYGNQNNVSLIVGAPKFDT 81
            :|:|:.|     ...:|:|:.:.:.|..|:..|||:::...:...|.:       :::|:|....
 Frog    12 LTALLKL-----TESFNVDVKNGLSFSGSAEDMFGYTVQQFENDEGKW-------VLIGSPLEGQ 64

  Fly    82 SRYQQGVTEAGGVFKCSLN-DDDCKLVPFDSKGN-NRNVD-KEVVDRKSYQWLGATVATGRDSDL 143
            .:::.     |.|:||.:: ..:|      ||.| .||.. .::::.|....:|:|:........
 Frog    65 PKHRM-----GDVYKCPVHMPSNC------SKLNLPRNTSIPDIIEVKENMAMGSTLVKNPKGGF 118

  Fly   144 VVACAPRYV-----FHTMT-----------------PS--------------------------- 159
             :||.|.|.     ||..|                 ||
 Frog   119 -LACGPLYAYRCGSFHYTTGICSNVSSSFEVLNAIAPSVQGCSNQLDIVIVLDGSNSVYPWESVN 182

  Fly   160 -------RAFRIDPVGTCF--------TSH--NFEEFYEVSPCRTNNWGYHRQGSCQA------- 200
                   :...|:|..|..        .:|  |...:...:..|..:.|..::|..|.
 Frog   183 YFLQKLLKNMNINPNQTQVGIVQYGENVTHEFNLNTYDSTAKVRQASLGIKQRGGSQTMTALGID 247

  Fly   201 ------------------------------------------------GFSAAINGN-------- 209
                                                            .||.||.|:
 Frog   248 TARKEAFTEARGARKGVKKVMVVVTDGESHDNYRLNSVIKECETDDIQRFSIAILGSYNRGNLST 312

  Fly   210 -----------------------------------GSRLF------------------------- 214
                                               |.|:|
 Frog   313 ETLVEEIKSIASEPKEKHFFNVSDELALLNIVESLGERIFALEATNEERASSFQMEMSQTGLSAH 377

  Fly   215 -------IGAPGSWYWQGQTYSIPPDAKFPFKPPLYQPFGTGGMASSHDVTRPENQVF--STSES 270
                   :||.|::.|.|....:..||                      ...|.||.|  .|.|.
 Frog   378 YSKDWAMLGAVGAYDWNGTVVMVNSDA----------------------TLIPNNQTFRKRTDEK 420

  Fly   271 ASVNDD--SYLGYSMVTGDFDGDRSEDVAI-GMPRGGNLVGRIVVNRWNMANI---FNITGRQIG 329
               |:.  :||||::.:....|   |::.| |.|| .|..|::::.:.|...|   ..:.|.|||
 Frog   421 ---NEPLAAYLGYTLSSASVHG---EEIYIAGQPR-YNHSGQVIIYKLNGEEIEVLQTLNGEQIG 478

  Fly   330 EYFGYSLATSDVDGDGLDDLLI-GAPMYTDPDNVEGKYDVGRVYI----------------LLQG 377
            .|||..|.|.|||||.:.|:|| |||||..    ..|.:.|:||:                |.|.
 Frog   479 SYFGSVLTTVDVDGDSISDILIVGAPMYMG----SAKQEQGKVYVYRIHGKEMHYQMSLEPLNQT 539

  Fly   378 GPTEEKRWTTEHIRDGYHSKGRFGLALTTLGDVNGDGYGDFAVGAPYDGPEGRGVVYIFHGSPMG 442
            ..:::|..:.::.........|||.|:..:.|:|.||:.|.|:|||.:| :.||.|||:|||  |
 Frog   540 CCSQQKDISCQNENQNEPCGSRFGTAIAAVTDLNLDGFNDVAIGAPLEG-DHRGAVYIYHGS--G 601

  Fly   443 PLAKPSQIIKSEQLVEG--APYPRTFGFALSGGLDMDGNTYPDLAVGAYSSDQVFIFKSRPVAAV 505
            ...|.:.   ::::..|  ....|.||.::.|.:|::|:...|:.:|....  ..:|.||.||.:
 Frog   602 KSIKENY---AQRIPSGGDGKKVRFFGQSIHGEMDLNGDGLTDVTIGGLGG--ASLFWSRDVAEI 661

  Fly   506 NAETSFASNSKLISLDDRSCQLVRDHKKVPCMLLTTCWSY---TGRYLPEQLDFDVSWLLDAKKL 567
            ...|.|..|:  |:::.:.|.:  .::...|:....|::.   :|.......|...:..||:.:.
 Frog   662 TVTTEFTPNA--INIEKKDCTV--SNRPTVCIKARFCFNLLLKSGEDKKASSDIIYTITLDSPRY 722

  Fly   568 LNPRMFFLRDEGKNIRNQTIRLNYGQKYCLNETVYLLDKVQDKLTPLEVEARYNLRSSRPLDPMV 632
            .:..:|   ::.::.:.|.:..:.|.  |||...|.::| .|.|..:.|...:|..     ||.
 Frog   723 ASRVLF---NDSQDRKFQGVMGHKGN--CLNHDFYTVEK-PDFLNSINVSVEFNFP-----DPE- 775

  Fly   633 RHRRSILEPVIDQNREIVLRDAINIQKNCGPDNICEPDLKLKVS-TVDKYLFGSPEPLV------ 690
                  ..||:...........|....:||.:..|..||.|... ::|...|.  |.:|
 Frog   776 ------KGPVLSSELPNFYNSYIPFTMDCGSEQKCITDLVLDAEISMDGISFN--EAIVKPTKDK 832

  Fly   691 --IEVFISNTNEDAFEAAFYMVTPPDLQFRKLQQLGEKKDTPITCSPPTPENNHTLKCDIGNP-L 752
              :.:.:.|..:.|:.|...:...|::    :....|.|. .::|     |::|.:.|.||.| |
 Frog   833 FNLTLTVKNMKKSAYNARVIVKYSPNI----ILAATEDKQ-KVSC-----ESDHDVTCKIGYPFL 887

  Fly   753 ESGKIAHFKISLVPEEKYGSSSSYD---FYWEANSTNLEKPGSEYDNKIRQSVGI----WVDTDL 810
            :..::..|||:.    ::.||...|   .:..|.|.:.|||.:..:|:...:..:    |:....
 Frog   888 KKDEMISFKITF----QFNSSHLLDNTFIFVNATSDSEEKPETLMNNRKNITFTVKYESWLTFVS 948

  Fly   811 DIKGTSLPDYQLYKADDYKELENATKEDDIGPQVVHIYEIRNNRPSIIEEAEVFIHLPYETIVGD 875
            ..|...:|   :...|......|:|  :.||.:|...|.||.|....:.:....:..||:|...:
 Frog   949 STKEFHVP---IAANDSIPATINST--EAIGAEVNIHYVIRKNDFIPMPKVSFRLSFPYKTPDNN 1008

  Fly   876 PLMYLLN 882
            .|:||.|
 Frog  1009 ILLYLTN 1015

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
if	NP_001162777.1	Int_alpha	46..110	CDD:214549	11/64 (17%)
		Int_alpha	275..>316	CDD:214549	12/43 (28%)
		Int_alpha	398..451	CDD:214549	24/52 (46%)
		Int_alpha	466..>497	CDD:214549	7/30 (23%)
		Integrin_alpha2	499..893	CDD:285619	88/404 (22%)
		DUF2756	<1120..1178	CDD:298627
itga1	XP_002933090.3	vWFA	163..343	CDD:412136	14/179 (8%)
		Int_alpha	477..>524	CDD:214549	24/50 (48%)
		Int_alpha	559..612	CDD:214549	24/58 (41%)
		Integrin_alpha2	655..1066	CDD:400650	88/404 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910