Protein Alignment if and itga11

DIOPT Version :9

• Sequence 1: NP_001162777.1
• Gene: if / 32661
• FlyBaseID: FBgn0001250
• Length: 1396
• Species: Drosophila melanogaster
• Sequence 2: XP_017947982.1
• Gene: itga11 / 100489152
• XenbaseID: XB-GENE-483822
• Length: 1188
• Species: Xenopus tropicalis
• Alignment Length: 1139
• Identity: 252/1139 - (22%)
• Similarity: 399/1139 - (35%)
• Gaps: 383/1139 - (33%)

  Fly     8 RRRMALHCPITSLILLLIAMSAHGYNIDLPSYVRFRQSSNSMFGFSIAMHK--GRSGFYGNQNNV 70
            ||.||      :..|.|:......:|||.........|.::.||:::..|:  |:..
 Frog     5 RRLMA------AWALCLLPGLTDTFNIDTKRPRIISGSKDAFFGYTVQQHQIAGKKW-------- 55

  Fly    71 SLIVGAPKFDTSRYQQGVTEAGGVFKCSLNDD---DC-KLVPFDSKGNNRNVDKEVVDRKSYQWL 131
             |:|||| ||.:    |..:.|.::|||:.:|   || ||      |..|.....|.:||....|
 Frog    56 -LVVGAP-FDVN----GPQKTGDIYKCSVTNDTSNDCTKL------GIGRVTLSNVSERKDNMRL 108

  Fly   132 GATVATGRDSDLVVACAPRY-------VFHTMTPSRA---FRIDPV------------------- 167
            |.::.|....:..|||:|.:       .:.|...||.   ||...:
 Frog   109 GMSLVTNPKDNSFVACSPLWSHECGSSYYTTGMCSRVNSNFRFSRIVAPALQRCPTFMDIVIVLD 173

  Fly   168 GT----------CFTSHNFEEFYEVSPCR-----------------TNNWG-------------- 191
            |:          .|.....::|| ::|.:                 .||:.
 Frog   174 GSNSIYPWVEVQSFLISILQKFY-IAPGQIQVGVLQYGETVVHEFYLNNYRSVTDVVEAAKRIEQ 237

  Fly   192 ----------------------------------------------------------------- 191
                                                                             
 Frog   238 RGGTETRTALGIEKAVTEAFQRGGRKGAKKVMIVITDGESHDSPDLQRVIESSEKDNITRYAVAV 302

  Fly   192 ---YHRQG--------------------------------------------------------- 196
               |:|:|
 Frog   303 LGYYNRRGINPEAFLNEIKYIASDPDDKHFFNVTDEAALKDIVDALGERIFSLEGGTNKNETSFG 367

  Fly   197 --SCQAGFSAAINGNGSRLFIGAPGSWYWQGQTYSIPPDAKFPFKPPLYQPFGTGGMASSHDVTR 259
              ..|||||:.:..:|  :.:||.|::.|.|.........|.                    :.|
 Frog   368 LEMSQAGFSSHVVEDG--ILLGAVGAYDWNGAVLKETSSGKV--------------------IPR 410

  Fly   260 PENQVFSTSESASVNDDSYLGYSMVTGDFDGDRSEDVAIGMPRGGNLVGRIVVNRWNMANIFNIT 324
            .|:.:....:... |..:||||: ||......|......|.|| .|..|:::|  :.|....|:|
 Frog   411 RESYLKEFPDELK-NHGAYLGYT-VTSVMTWQRVRIYVAGAPR-FNHTGKVIV--FTMHGAENMT 470

  Fly   325 ------GRQIGEYFGYSLATSDVDGDGLDD-LLIGAPMYTDPDNVEGKYDVGRVYILLQGGPTEE 382
                  |.|||.|||..:.:.||||||:.| ||:|||||.    ::| ::.|||.:.:    ..|
 Frog   471 IHQALQGNQIGSYFGGEMDSVDVDGDGVTDILLVGAPMYF----IDG-WERGRVSVFV----LRE 526

  Fly   383 KRWTTEHIRDGY------HSKGRFGLALTTLGDVNGDGYGDFAVGAPYDGPEGRGVVYIFHGSPM 441
            :::    |.:|:      ....|||.::..:.|:|.|.|.|..||||.: ...:|.:|||||...
 Frog   527 RQF----IHNGFLQDLNSSQNSRFGSSIAAVPDLNQDLYNDVVVGAPLE-DNHKGAIYIFHGLRK 586

  Fly   442 GPLAKPSQIIKSEQLVEGAPYPRTFGFALSGGLDMDGNTYPDLAVGAYSSDQVFIFKSRPVAAVN 506
            ..|.|..|.|.:.:|..|..|   ||..:.|.:||:.:...|||||  |.....:..:|.|..:|
 Frog   587 NILKKYKQRISAAELAPGLVY---FGCNIHGEMDMNEDGLVDLAVG--SMGNAVLLWTRSVVKIN 646

  Fly   507 AETSFASNSKLISLDDRSCQLVRDHKKVPCMLLTTCWS-------YTGRYLPEQLDFDVSWLLDA 564
            |...|  ....|::..:.|.  |:.::..||....|:|       :.|:.:  .:.::||  :|.
 Frog   647 ATMHF--EPPKINIFSKDCH--RNGREATCMSAFICFSPMFKAQQFQGQNV--AIKYNVS--IDE 703

  Fly   565 KKLLNPRMFFLRDEGKNIRNQTIRLNYGQKYCLNETVYLLDKVQDKLTPLEVEARYNLRSSRPLD 629
            ::.: ||.......|.....:|||...|...|.....::|| ..|.:.|:.....|.|..|..
 Frog   704 RRYI-PRAIIDDIGGDKHFVKTIRATSGHNQCQQLNFHVLD-TADYVKPITFSLEYELAFSDQ-- 764

  Fly   630 PMVRHRRSILEPVIDQNREIVLRDAINIQKNCGPDNICEPDLKLKV------------------- 675
                      .||::::....|:.::.....|..|..|.|||.|.|
 Frog   765 ----------GPVLEEDWPTSLKVSVPFWNGCNQDERCVPDLYLDVKHDIPTALEYCQRFLYRTQ 819

  Fly   676 -------STVDKYLF---GSPEPLVIEVFISNTNEDAFEAAFYMVTPPDLQFRKLQQLGEKKDTP 730
                   |..|..:|   .|...:.:||.:.|..|:|:..|..:....:|||..| ...|..|..
 Frog   820 SACTEFISAFDNSVFIIQRSRRRVALEVVLENRGENAYSTALNISHSQNLQFASL-ITKEDSDIK 883

  Fly   731 ITCSPPT--PENNHTLKCDIGNPL--ESGKIAHFKISLVPEEKYGSSSSYDF------YWEANST 785
            |.|....  |   ||..|::..|.  ...|:| |::..       ..|.|.|      :..|.|.
 Frog   884 IECKSDDRFP---HTKTCNVSYPFFRAKAKVA-FRLDF-------EFSKYQFLPFLQVHLSAGSD 937

  Fly   786 NLEKPGSEYDNKIRQSVGIWVDTD-LDIKGTSLPDYQLY---KADDYKELENATKEDDIGPQVVH 846
            :.|:..:.:||::.....:..::| |..:.:||..|::.   .||.|    ||     |||....
 Frog   938 SEEQESTRFDNEVLLDFHLKYESDLLFTRHSSLNHYEITSEGSADRY----NA-----IGPPFNS 993

  Fly   847 IYEIRNNRPSIIEEAEVFIHLPYETIVGDPLMYL 880
            .::|: |.....||..:.|.:|..|..|:.|::|
 Frog   994 SFKIQ-NLGFFPEEINLKITVPVATRGGNRLLFL 1026

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
if	NP_001162777.1	Int_alpha	46..110	CDD:214549	21/69 (30%)
		Int_alpha	275..>316	CDD:214549	13/40 (33%)
		Int_alpha	398..451	CDD:214549	21/52 (40%)
		Int_alpha	466..>497	CDD:214549	11/30 (37%)
		Integrin_alpha2	499..893	CDD:285619	99/432 (23%)
		DUF2756	<1120..1178	CDD:298627
itga11	XP_017947982.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910