Protein Alignment goe and Nep2

DIOPT Version :10

• Sequence 1: NP_573160.1
• Gene: goe / 32660
• FlyBaseID: FBgn0027528
• Length: 879
• Species: Drosophila melanogaster
• Sequence 2: NP_001246914.1
• Gene: Nep2 / 40588
• FlyBaseID: FBgn0027570
• Length: 774
• Species: Drosophila melanogaster
• Alignment Length: 741
• Identity: 157/741 - (21%)
• Similarity: 271/741 - (36%)
• Gaps: 178/741 - (24%)

  Fly   162 LCLDKECVESSRQLLLWANTSKSPCHETYEWACG------NFASDYANHEYFVI---KRGEWNYE 217
            :||.:||:.::..:|........||...||:|||      |...|..:...|.:   |..|...:
  Fly    83 VCLTQECIHTASTVLRKMKPEVEPCDNFYEFACGTYLEEENIPDDKVSISTFSVISDKLQEQLKD 147

  Fly   218 TYNEYQELNELNRFIAMLPNSQEGSVESTVSSLYRSCRETDVLDKSQSDLL----LKRAINAVYG 278
            .....:...|...|  .|||           .||::|     ::|:..:.|    :.|....:.|
  Fly   148 IITAERPETEPKHF--RLPN-----------LLYKAC-----MNKTLIETLGPEPITRVAERLGG 194

  Fly   279 WQAFR-DS-NRLQSWEYKRVLVVLQAKHGIFPYYRVTVENGFSNPHDYV---------------- 325
            |...: || |...||.::.     |.|.     :|..   |||  .||:
  Fly   195 WPLIKGDSWNADDSWTWQE-----QVKK-----FRTA---GFS--MDYIIDFSIGVDLQNSTKRL 244

  Fly   326 ITLDEGELGLPDKYFYGNDADEEVVRGYKLLLRDFAINMGIVSREADLFADDIFHYERRIVNHIE 390
            |.||:..|.|..:|.. ...:|.:|..|...:.|.|:..| .:|       |:...|..:....|
  Fly   245 IDLDQSSLALSREYLV-KGFNETLVTAYYKYMVDIAVLFG-ANR-------DLAKTELLLSLEFE 300

  Fly   391 DAKADANRPINK---------LMRLADLKIKAPSLPILESLQAIFPK-TKITEDTEVLVRDPEVM 445
            .|.|:.:.|..|         |...|.|:...|.:..::.:.|:.|: ..:.||..:.:..|...
  Fly   301 MALANISWPNEKRRNSSELYNLRTPAQLQAAYPYVQWVDYMNALLPEGLNVAEDEMINLSVPSFF 365

  Fly   446 HALSVLLSTSDKKPINNFIVWSLARKMLPHLSKEYRTLAETFDHALYGRTASYPRWLICSKVVR- 509
            ..|..||:.:.|:.|.|::.|.:....:..||:|:|.....:..||.||.....||..|..:..
  Fly   366 EDLGKLLAKTPKRVIANYMFWRIHGFSVGFLSEEFRKRQLQYATALSGRQEQEARWKECVDIATS 430

  Fly   510 ----------DWLPFAVDALQQQPPRQQFETMTSKSRGLNKTQGNEELLKLMFFSLRNQLKDSLE 564
                      |.|..:|.:|.   ..:.|. ..||:..|.           |...:||...|.|:
  Fly   431 SMDEVCEDDFDSLGISVGSLY---VGKHFH-KDSKANALE-----------MVNEIRNVFNDILD 480

  Fly   565 QAKWLEPAARQFIQKKLNEMRLQFGIPDEVLQQPTYLAQYYNELILN-----------NVFFVEH 618
            :..|::...::..:.||:.|....|.|||:|.... ||.||.:|.::           |:|..:
  Fly   481 EVNWMDAKTKKEAKLKLHSMATHIGYPDEMLDNEK-LAAYYAKLDIDPDKYFESFLGMNIFGTD- 543

  Fly   619 LEWIWTFRRSQMEKKLGPLAILDVIVSEMYTRDNPQAIA---YSNKLNMLLVSKVLISSNYYDYR 680
                ::|.:.::     |:...|      :.|....||.   ||:..|.:.....::..::::.:
  Fly   544 ----YSFNKLRL-----PVNKTD------WVRHARPAIVNAFYSSLENSIQFPAGILQGHFFNAQ 593

  Fly   681 YPVAVNFARIGTDILEALIDNFSTFLLQFNTQSTDISDAAPEIRYAQPDVNCLAAGQPPRLVHEL 745
            .|..:||..||..|...:...|.....||:.:. ::.|      :..||.......:...::.:.
  Fly   594 RPKYMNFGAIGYVIGHEITHGFDDQGRQFDVKG-NLRD------WWHPDTQKAYLAKAKCIIEQY 651

  Fly   746 NELSSNALKSFHVTLSAARTAARALSNFVNAIDAGSAIQGSGI-DQANTYEALGLTRR------- 802
            ...:.                 ||....:|.|:.    ||..| |.....|:....||
  Fly   652 GNYTE-----------------RATGLNLNGINT----QGENIADNGGVKESYIAYRRWAEKHGP 695

  Fly   803 -LRIPGLRSFNENELFTLSYMQQHCS 827
             .::||| .:...::|.::..|..|:
  Fly   696 EAKLPGL-DYTPEQMFWVAAGQTWCA 720

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
goe	NP_573160.1	GluZincin	184..>692	CDD:472708	127/573 (22%)
Nep2	NP_001246914.1	M13	104..772	CDD:341056	152/720 (21%)