Protein Alignment goe and KEL

DIOPT Version :10

• Sequence 1: NP_573160.1
• Gene: goe / 32660
• FlyBaseID: FBgn0027528
• Length: 879
• Species: Drosophila melanogaster
• Sequence 2: XP_005250050.1
• Gene: KEL / 3792
• HGNCID: 6308
• Length: 744
• Species: Homo sapiens
• Alignment Length: 809
• Identity: 174/809 - (21%)
• Similarity: 300/809 - (37%)
• Gaps: 207/809 - (25%)

  Fly    82 AGGAGGRTPAAITPNSTHPSANGLRALLLPGRRSFDALMSLSRKRRILYVTTACLCALLLLIIIL 146
            |||.|.......||....|         :.|.|.:      :..||:|   ||.|...|||...:
Human    29 AGGMGTLWSQESTPEERLP---------VEGSRPW------AVARRVL---TAILILGLLLCFSV 75

  Fly   147 LLAFWPEVPFYLRAPL-CLDKECVESSRQLLLWANTSKSPCHETYEWACGNFASDYANHEYFVIK 210
            ||.:    .|....|. |....|::.....|...|||.:||.:.:.:|||...
Human    76 LLFY----NFQNCGPRPCETSVCLDLRDHYLASGNTSVAPCTDFFSFACGRAK------------ 124

  Fly   211 RGEWNYETYNEYQEL-----NELNRFIAMLPNSQEGSVESTVSSLYRSCRETDVLDKSQSDLLLK 270
                  ||.|.:|||     |.|.|.:.:..:...||.|......|.||.:|..::.:.:. .|:
Human   125 ------ETNNSFQELATKNKNRLRRILEVQNSWHPGSGEEKAFQFYNSCMDTLAIEAAGTG-PLR 182

  Fly   271 RAINAVYGWQAFRDSNRLQSWEYKRVLVVLQAKHGIFPYYRVTVENGFSNPHDYVITLDEGELGL 335
            :.|..:.||   |.|.:..|..:.|.|.:|.:::|.||::|..:....::||..||.:|:.|..:
Human   183 QVIEELGGW---RISGKWTSLNFNRTLRLLMSQYGHFPFFRAYLGPHPASPHTPVIQIDQPEFDV 244

  Fly   336 PDKYFYGNDADEEVVRGYKLLLRDF----------------------AINMGIVSREADLFADDI 378
            |.|    .|.::::   |..:.|::                      ::::.|.||        :
Human   245 PLK----QDQEQKI---YAQIFREYLTYLNQLGTLLGGDPSKVQEHSSLSISITSR--------L 294

  Fly   379 FHYERRIVNHIEDAKADANRPINKLMRLADLKIKAPSLPILESLQAIFPKTKITEDTEVLVRDPE 443
            |.:.|    .:|..:|...  :.:::.:..||..||::..|..|||.|....::....::|.|.|
Human   295 FQFLR----PLEQRRAQGK--LFQMVTIDQLKEMAPAIDWLSCLQATFTPMSLSPSQSLVVHDVE 353

  Fly   444 VMHALSVLLS---TSDKKPINNFIVWSLARKMLPHLSKEYRTLAETFDHALYGRT-----ASYPR 500
            .:..:|.|:.   ...:..:.:.::..|...:.|.|..:::.........|...|     .:.||
Human   354 YLKNMSQLVEEMLLKQRDFLQSHMILGLVVTLSPALDSQFQEARRKLSQKLRELTEQPPMPARPR 418

  Fly   501 WLICSKVVRDWLPFAVDALQQQPPRQQFETMTSKSRGLNKTQGNEELLKLMFFSLRNQLKDSLEQ 565
            |:.|   |.:...|....|.....|:.|...|..:           .:|| |.::|:.|...|..
Human   419 WMKC---VEETGTFFEPTLAALFVREAFGPSTRSA-----------AMKL-FTAIRDALITRLRN 468

  Fly   566 AKWLEPAARQFIQKKLNEMRLQFGIPDEVLQQPTYLAQYYNELILNNVFFVEHLEWIWTFRRSQM 630
            ..|:....:...|.|:.:::::.|..:..| :|....|.||::.|.:.|....|..:.:.|...:
Human   469 LPWMNEETQNMAQDKVAQLQVEMGASEWAL-KPELARQEYNDIQLGSSFLQSVLSCVRSLRARIV 532

  Fly   631 EKKLGPLAILDVIVSEMYTRDNPQ----------AIAYSNKLNMLLVSKVLISSNYYDYRYPVAV 685
            :..|.|               :||          ...||...::::....|:...::...||.||
Human   533 QSFLQP---------------HPQHRWKVSPWDVNAYYSVSDHVVVFPAGLLQPPFFHPGYPRAV 582

  Fly   686 NFARIGTDILEALIDNFSTFLLQFNTQSTDISDAAPEIRYAQPDVNCLAAGQPPRLVHELNELSS 750
            ||...|:.:...|:..|...||                    |. .|||.             .:
Human   583 NFGAAGSIMAHELLHIFYQLLL--------------------PG-GCLAC-------------DN 613

  Fly   751 NALKSFHVTLS--------AARTAAR-ALSNFVNAIDAGS---AIQGSGIDQANTYEALGLTRRL 803
            :||:..|:.|.        .:||:.. :|:...||.|.|.   |:|...            .|.|
Human   614 HALQEAHLCLKRHYAAFPLPSRTSFNDSLTFLENAADVGGLAIALQAYS------------KRLL 666

  Fly   804 R------IPGLRSFNENELFTLSYMQQHC 826
            |      :|.| ..:..::|..||.|..|
Human   667 RHHGETVLPSL-DLSPQQIFFRSYAQVMC 694

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
goe	NP_573160.1	GluZincin	184..>692	CDD:472708	114/552 (21%)
KEL	XP_005250050.1	M13	109..742	CDD:341056	146/707 (21%)