Protein Alignment goe and nep-8

DIOPT Version :10

• Sequence 1: NP_573160.1
• Gene: goe / 32660
• FlyBaseID: FBgn0027528
• Length: 879
• Species: Drosophila melanogaster
• Sequence 2: NP_001309548.1
• Gene: nep-8 / 184631
• WormBaseID: WBGene00017553
• Length: 686
• Species: Caenorhabditis elegans
• Alignment Length: 791
• Identity: 137/791 - (17%)
• Similarity: 276/791 - (34%)
• Gaps: 232/791 - (29%)

  Fly   139 LLLLIIIL----------------LLAFWPEVPFYLRAPLCLDKECVESSRQLLLWANTSKSPCH 187
            |||||:.|                ||:...:|.   ...||...||:..|.:||.:.:.|..||.
 Worm    19 LLLLIVFLAMVTVHIKVEPVNLDELLSIGNDVD---SKNLCDSPECITLSHELLNYQDPSVDPCV 80

  Fly   188 ETYEWACGNFASDYANHEYFVIKRGEWNYETYNEYQE-----LNELNRFIAMLPNSQEGSVESTV 247
            :.::.:||.|      ||..|         :.:..|:     ..::..|:..:.||...| |:.:
 Worm    81 DFFQHSCGRF------HEQSV---------SESRLQKKKHILRKQIREFLHKIQNSTSKS-ENLM 129

  Fly   248 SSLYRSCRETDVLDKSQSDLLLKRAINAVYGWQAFRDSNRLQSW---------------EYKRVL 297
            ..::..|..:    |..|:...|.:.:|::  ..|.|..::.:|               |....|
 Worm   130 KLVFDKCEAS----KKTSNDNYKISRDAIH--DVFNDIKKIGAWPLLDKNWDGSKFDLNEMLSNL 188

  Fly   298 VVLQAKH-GIFPY-YRVTVENGFSN--PHDYVITLDEGELGLPDKYFYGN----DADEEVVRGYK 354
            |.|.|.: |:|.. :|:..|..|..  |....|..:...:.:..:....|    |::|
 Worm   189 VKLGATNLGLFQLDFRILTEGKFVRIAPTLGSIVHNSTMISMISEILEANGVQPDSEE------- 246

  Fly   355 LLLRDFAINMGIVSREADLFADDIFHYERRIVNHIEDAKADANRPINKLMRLADL--KIKAPSLP 417
                        :|:|.:.::.    .:.::..:....|...:.|..:.:..:.|  ::..||
 Worm   247 ------------ISKEFEEYSS----LQMKLAKYQSSGKLSISLPGVRSINFSSLITEMIHPS-- 293

  Fly   418 ILESLQAIFPKTKITEDTEVLVRDPEVMHALSVLLSTSDKKPINNFIVWSLARKMLPHLSKEYRT 482
               .:..||.|.::......|........:|..::.::..|.:.||::::       ::...|..
 Worm   294 ---RVSKIFGKIRVVTSEHPLFFKSNETESLDTIIESTSNKTLANFLIFN-------YIQSSYNI 348

  Fly   483 LAETFDHALYGRTASYPRWLICSKVVRDWLPFAVDALQQQPPRQQFETMTSKSRGLNKTQGNEEL 547
            :    ..|..|.         |.           |.::::.||..........    ..:||.:.
 Worm   349 M----KGARRGN---------CE-----------DDVRREFPRASLRVFMRNF----VDKGNRDG 385

  Fly   548 LKLMFFSLRNQLKDSLEQAKWLEPAARQFIQKKLNEMRLQFGIPDEVLQQPTYLAQYYNELI--- 609
            :|.:...|:....:.::..:.|.|..::.:.||:..:::..|.||......|...::.|..:
 Worm   386 VKKLTEELKKNTLEMIQDTENLAPPVKESMLKKVEAIKVTIGYPDHFDPPGTLDKEFENFDLDST 450

  Fly   610 ---------LNNVFFVEHLEWIWTFRRSQMEKKLGPL-AILDVIVSEMYTRDNPQAIAYSNKLNM 664
                     ||.:...:.:|:|      ..|..:.|: .:|.|..:            |....|.
 Worm   451 DSYYRIFQKLNRLRSEQQMEFI------AGETPISPIKEVLKVNAN------------YKRSKNA 497

  Fly   665 LLVSKVLISSNYYDYRYPVAVNFARIGTDILEALIDNFSTFLLQFNTQSTDISDAAPEIRYAQPD 729
            |.|....:...::|..||..||..             ||.||:            |.||.:: .|
 Worm   498 LTVFAPFLDDPFFDITYPDYVNLF-------------FSGFLI------------AHEIGHS-VD 536

  Fly   730 VNCLAAGQPPRLVHELNELSSNALKSFHVTLSAARTAARALSNFVNAIDA--GSAIQGS-GIDQA 791
            .|.|.        ::.|....:.::..||| ...:.....:..:.|..|.  |..:.|: .|::.
 Worm   537 ANGLG--------YDENGKPMDGIRLEHVT-EYGKQGQCLVDQYDNYDDPVYGKKMNGTHSINEI 592

  Fly   792 -----------NTYEALGLTRRLRIPGLRSFNENELF----TLSYMQQHCSTTIAD--KD----- 834
                       ..|:.:..::.|.:.||:..|.::|:    :|.:.::..:.::.:  ||
 Worm   593 IADWVGHEVTWRAYKKMDTSKMLSLIGLKDINMDQLYFRVQSLLFCRERDTISLEETLKDVYPTD 657

  Fly   835 -------YARI 838
                   |||:
 Worm   658 NFRVNGAYARV 668

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
goe	NP_573160.1	GluZincin	184..>692	CDD:472708	89/550 (16%)
nep-8	NP_001309548.1	M13	76..664	CDD:341056	117/725 (16%)