Protein Alignment goe and nep-22

DIOPT Version :10

• Sequence 1: NP_573160.1
• Gene: goe / 32660
• FlyBaseID: FBgn0027528
• Length: 879
• Species: Drosophila melanogaster
• Sequence 2: NP_509528.1
• Gene: nep-22 / 181144
• WormBaseID: WBGene00020788
• Length: 798
• Species: Caenorhabditis elegans
• Alignment Length: 751
• Identity: 136/751 - (18%)
• Similarity: 256/751 - (34%)
• Gaps: 176/751 - (23%)

  Fly   170 ESSRQLLLWANTSKSPCHETYEWACGNFASDYANHEYFVIKRGEWNYETYNEYQELNELNRFIAM 234
            :::..||...:.:..||.:.|.:.|..|..:..     :.|.|.....||::.| ::..:..:|.
 Worm    70 QAANYLLNGLDDTVDPCQDFYAFTCNKFLQNTD-----LQKLGRSRLGTYDQAQ-VDVYSEIVAA 128

  Fly   235 L-----PNSQEGSVESTVSSLYRSCRETDVLDKSQSDLLLKRAINAVYGWQAFRDSNRLQSWEYK 294
            |     .::.....|....:.:.:|: .::...:....::...|.:::|...|.......:.:|.
 Worm   129 LSKIDVTSTTTSKTERITKAAFETCK-NNLASPADKTAVVYAEITSLFGGVPFFGEPLKTNVDYW 192

  Fly   295 RVLVVLQAKH--GIFPY------YRVTVEN-------GFSNPHD------YVITLDEGELGLPD- 337
            .|...::.||  |...|      |:...:|       |.|...|      |:..:::....:.|
 Worm   193 MVAGQIEQKHAVGTLTYTIASSDYKDHTKNALYTGPPGLSLARDFYVKPQYIAEVNQRVSDVNDL 257

  Fly   338 --------KYFYGND----ADEEVVRGYKLLLRDFAINMGIVSREADLFADDIFHYERRIVNHIE 390
                    |...|.|    |.:|||        :|.:.:.:.|     :.||:....::..|...
 Worm   258 LTAFANAAKKNVGADALLAAAQEVV--------NFEVQIAMAS-----WPDDLLRNYQQQYNPYN 309

  Fly   391 DAKA-DANRPINKLMRLADLKIKAPSLPILESLQAIFPKTKITEDTEVLVRDPEVMHALSVLLST 454
            .|.| .|.|.||....|..|.....|    ::.||.:         .::|.:|.....|:   |.
 Worm   310 IASATTAYRAINWKSYLGQLFHGVAS----DADQANY---------NIVVTEPSYFAWLN---SV 358

  Fly   455 SDKKPINNFIVWSLARKMLPHLSKEYRTLAETFDH-----ALYGRTASYPRWLI----------- 503
            .|.|..|:.:|   |..|:..|      ||:..|.     |......:|..:.:
 Worm   359 FDGKTSNSTVV---ANYMIAQL------LADESDFINPATAKVSSDTNYIHYALRNGRGIKKIGK 414

  Fly   504 --------------CSKVVRDWLPFAVDALQQQPPRQQFETMTSKSRGLNKTQGNEELLKLMFFS 554
                          |..::..::|:...          :..:.|||. .||.|.:   :|.....
 Worm   415 REYRMADLDGISEGCMDLLTAYMPYGTG----------YVYVKSKSE-RNKVQAD---VKDQTTL 465

  Fly   555 LRNQLKDSLEQAKWLEPAARQFIQKKLNEMRLQFGIPDEVLQQPTYLAQYYNELILNNVFFVEHL 619
            :.|..:..::...|::..::.....|.:.:...||.|:.:...       :|:....:.:..::.
 Worm   466 IINNFQGMIDSLNWMDTFSKNRAHNKSDSLVKNFGWPEAMFGD-------FNDFTTVDAYNQDYA 523

  Fly   620 EWIWTFRRSQMEKKLGPLAILDV---------IVSEMYTRDN----PQAIA--YSNKLNMLLVSK 669
            ..|..:.:.:.: ..|..|:|..         |:.|...|.|    |..:.  |..:.|.:....
 Worm   524 SIIDLYTKDKND-IYGIFAVLKKGMEVREFFRIMGEPADRTNFLQSPAMVNAWYQPERNSITFPY 587

  Fly   670 VLISSNYYDYRYPVAVNFARIGTDILEALIDNFSTFLLQ--FNTQSTDISDAAPEIRYAQPDVNC 732
            ...:..||:..||.|.|||..|......|...:....:|  ||.:.||.|    ..:....|.|.
 Worm   588 AAWNPPYYNLNYPQAYNFAGQGGTGGHELTHGYDDEGVQFGFNGELTDCS----WNKCGWMDTNS 648

  Fly   733 LAAGQPPRLVHELNELSSNALKSFHVTLSAARTAARALSNFVNAIDAGSAIQGSGIDQA--NTYE 795
            .:.         ..:::...:..|.......:|.....:|  .|...|..|...|..||  .:|.
 Worm   649 SSG---------FIDMAQCVVTQFSTQCCPEKTGNIHCAN--GATTQGENIADLGGQQAAYRSYR 702

  Fly   796 ALGLTRRL-----RIPGLRSFNENELFTLSYMQQHC 826
            ....|.|.     |:|||.::..|::|.::|....|
 Worm   703 QYVATTRKGVEEDRLPGLENYTPNQIFWITYGYSWC 738

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
goe	NP_573160.1	GluZincin	184..>692	CDD:472708	104/592 (18%)
nep-22	NP_509528.1	M13	83..793	CDD:341056	134/738 (18%)