Protein Alignment goe and nep-1

DIOPT Version :10

• Sequence 1: NP_573160.1
• Gene: goe / 32660
• FlyBaseID: FBgn0027528
• Length: 879
• Species: Drosophila melanogaster
• Sequence 2: NP_496490.2
• Gene: nep-1 / 174787
• WormBaseID: WBGene00013926
• Length: 754
• Species: Caenorhabditis elegans
• Alignment Length: 771
• Identity: 145/771 - (18%)
• Similarity: 279/771 - (36%)
• Gaps: 194/771 - (25%)

  Fly   170 ESSRQLLLWANTSKSPCHETYEWACGNFA------SDYANHEYFVIKRGEWNYETYNEYQELNEL 228
            |:||.|....|.|..||.:.:|:||..:.      .|..::..|...|    .:...|.::|.|.
 Worm    71 EASRLLQKSLNLSLDPCDDFFEYACRAWVDSHPIPDDLTSYSQFTATR----EKVLAEMRKLYED 131

  Fly   229 NRFIAMLPNSQEGSVESTVSSLYRSCRET---------DVLDKSQSDLLLKRAINAVYG-WQAFR 283
            |   ..:|.|:..::   :..:|.:|.:|         |:|:|.::           || |....
 Worm   132 N---TSIPTSKSIAL---IKQIYNTCMDTEKHNAVGARDLLEKIKT-----------YGYWPMVH 179

  Fly   284 DSN-RLQSWEYKRVLVVLQAKHGIFPYYRVTVENGFSNPHDYVITLDEGELGL---PDKYFYGND 344
            :.. |..:::..::|........:..::.........|....:::.|:|.|||   ...|:....
 Worm   180 NEKWRESTFDLTKLLSNTIQSRDVSVFFDFGPAEDSRNVSRRLLSFDQGSLGLGYSTRDYYLDEK 244

  Fly   345 ADEEVVRGYKLL----LRDFAINMGIVSREADLFA--DDIFHYER---RIVNHIEDAKADANRPI 400
            ..|:.::.|:..    :|.:..:.|:...|:.:.:  |:|..:|:   :|:...||     .|..
 Worm   245 KYEKQMKAYRKYTIGKVRYYTEDAGMAVNESKIESDVDEIIAFEKEWAQILVAEED-----RRNY 304

  Fly   401 NKL---MRLADLKIKAPSLPILESLQAIFPKTKITEDT-------------EVLVRDPEVMHALS 449
            .||   .|..|||          ...:|....|:|..|             .:::.|.|.:..::
 Worm   305 TKLYNVRRFDDLK----------EYMSIIDWKKLTLSTTPFLVHSYLKTNPSIIISDVEYLQKMN 359

  Fly   450 VLLSTSDKKPINNFIVWSLARKMLPHLSKEYRTLAETFDHALYGRTASYPRWLICSKVVRDWLPF 514
            .||..:|.:.:.|:|:...|......:.|:|..|.:.|...:|||....|||..|.......|.:
 Worm   360 TLLQNTDPRIVTNYILLRWAGSWSQEIGKKYEDLQQEFAFQMYGRKQRQPRWKDCVSSAGGKLSY 424

  Fly   515 AVDALQQQPPRQQFETMTSKSRGLNKTQGNEELLKLMFFSLRNQLKDSLEQAKWLEPAARQFIQK 579
            |..::.   .|:.|:. .:|:..|:           |...|:...::.:....|::...:::..:
 Worm   425 ASGSMY---VRKYFDA-NAKNTTLD-----------MITDLQEAFRNMMHANDWMDAETKKYALE 474

  Fly   580 KLNEMRLQFGIPDEVLQQPTYLAQY----------YNELI------LNNVFFVEHLEWIWTFRRS 628
            |.::|..|.|.||.:|........|          :::|:      .||.::...||.:..|
 Worm   475 KADQMLKQIGYPDFILNDEKLDDWYKGLEGAPEDSFSQLVEKSIQWRNNFYYRRLLEPVNRF--- 536

  Fly   629 QMEKKLGPLAILDVIVSEMYTRDNPQAIAYSNKLNMLLVSKVLISSNYYDYRYPVAVNFARIGTD 693
               :.:...|:::..              ||...|.:.....::...::|.|:|.|:|:..||..
 Worm   537 ---EFISSAAVVNAF--------------YSPTRNAIAFPAGILQQPFFDARFPKALNYGGIGAV 584

  Fly   694 ILEALIDNFSTFLLQF-----------NTQSTDISDAAPEIRYAQPDVNCLAAGQPPRLVHELNE 747
            |...:...|.....||           ||.|:..::.          ..|:           :.:
 Worm   585 IGHEITHGFDDTGRQFDNVGNLRDWWDNTTSSKFNER----------TQCI-----------IEQ 628

  Fly   748 LSSNALKSFHVTLSAARTAARALSNFVNAIDAGSAIQGSGIDQA----NTYEALGLTRRLRIPGL 808
            .:...|:...:.::...|...      |..|.|      ||.||    .:|......:..|:|..
 Worm   629 YADVKLRGTDLRINGKLTQGE------NIADNG------GIKQAFKAYKSYLEKHGGQEARLPQF 681

  Fly   809 RSFNENELFTLSYMQQHCS------------TTIADKDYARIKPLVESQ--LAESY 850
            .|....:||.:.|.|..|.            |.....:.||:..::.:|  .||::
 Worm   682 ESLTNEQLFFVGYAQVWCGAKTPETKTLLLLTDPHSPETARVNTVLTNQPEFAEAF 737

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
goe	NP_573160.1	GluZincin	184..>692	CDD:472708	106/568 (19%)
nep-1	NP_496490.2	M13	85..751	CDD:341056	139/757 (18%)