Protein Alignment goe and nep-11

DIOPT Version :10

• Sequence 1: NP_573160.1
• Gene: goe / 32660
• FlyBaseID: FBgn0027528
• Length: 879
• Species: Drosophila melanogaster
• Sequence 2: NP_494538.1
• Gene: nep-11 / 173685
• WormBaseID: WBGene00017557
• Length: 848
• Species: Caenorhabditis elegans
• Alignment Length: 741
• Identity: 153/741 - (20%)
• Similarity: 274/741 - (36%)
• Gaps: 159/741 - (21%)

  Fly   152 PEVPFYLRAP----LCLDKECVESSRQLLLWANTSKSPCHETYEWACGNFASDYANHEYFVIKRG 212
            |||......|    :|....||.::...|...|||..||.:.:|:||                 |
 Worm   146 PEVTTSTEKPKEPEVCSTPGCVRAATHFLNAMNTSVDPCDDFFEFAC-----------------G 193

  Fly   213 EWNYE-------------TYNEYQELNELNRFIAMLPNSQEGSVES----TVSSLYRSCRETDVL 260
            :||.:             .|...|...:|...:     .||...||    ...:.||||     :
 Worm   194 QWNDQHPIPDDMYGFGTFAYAREQVRQQLRVLL-----EQEVVTESESINMARATYRSC-----M 248

  Fly   261 DKSQSDLL----LKRAINAVYGWQAFRDSNRLQSWEYKRVLVVLQAKHGIFPYYRVTVENGFSNP 321
            :|:|.|.|    |...:..:..|...:::.....:.:..:||..:..:|:..::::.:.....|.
 Worm   249 NKTQLDELMTGPLFETLTELGEWPLLQENWDKTKFNFTSLLVNSRRDYGVDVFFQLYIYADSKNT 313

  Fly   322 HDYVITLDEGELGL---PDKYFYGNDADEEVVRGYKLLLRDFA----INMGIVSREADLFAD--D 377
            ....:.:|:..|.|   ...|:.........:..|:..||..|    .:..:...|:::.||  .
 Worm   314 SRNTLFIDQSTLALGRGTRDYYLNTTLFSSHMTAYRKYLRQIAHLLKTDGNLTRSESEMNADIEK 378

  Fly   378 IFHYERRIVNHI--EDAKADANRPINKLMRLADLKIKAPSLPILESLQAIFPKTKIT----EDTE 436
            |..:|..:...|  ||.:.:..|..|| .::.||....|.:..:...|:|.| :.:|    .:||
 Worm   379 IIDFEIELAKIIVAEDERRNNTRLYNK-RQIQDLYNLLPQVDWVPFFQSIAP-SDLTHLFHNETE 441

  Fly   437 VLVRDPEVMHALSVLLSTSDKKPINNFIVWSLARKMLPHLSKEYRTLAETFDHALYGRTASYPRW 501
            :::.:.|.:..:|.|:..:|...:.|:::|.:.:..:.:|.:.:..:.:.|...:.|:..|.|||
 Worm   442 IIICEIEYLQHVSELIEKTDVGLLTNYVLWRVVQSNVRYLDERFEDIKQDFLKVMTGQQQSPPRW 506

  Fly   502 LICSKVVRDWLPFAVDALQQQPPRQQFETMTSKSRGLNKTQGNEELLKLMFFSLRNQLKDSLEQA 566
            ..|::|....||.|..|:..|...|:.:              ..|.|: |...|||...|.:.|.
 Worm   507 KDCAQVPSTVLPLAAGAIYVQAHFQESD--------------KHEALR-MIMHLRNSFADLVRQN 556

  Fly   567 KWLEPAARQFIQKKLNEMRLQFGIPDEVLQQPTYLAQYYNELILNN--VFFVEHLEWIWTFRRSQ 629
            .|::...:....:|.|.|....|.||.....|....||....|.::  .:::.....:|...| :
 Worm   557 DWMDEETKAVAIEKANSMINNIGYPDVTNDLPKLDKQYLGLSISDSDTYYYIMKKSVVWMQSR-E 620

  Fly   630 MEKKLGPLAILDVIVSEMYTRDNPQAIA---YSNKLNMLLVSKVLISSNYYDYRYPVAVNFARIG 691
            .:|...|.        :.:..|...|:.   ||.:.|.:.....::...::...:|.|||:..||
 Worm   621 FQKLTKPF--------DKHEFDISPAVVNAFYSPEKNAITFPAGILQPPFFSGTFPKAVNYGAIG 677

  Fly   692 TDILEALIDNFSTFLLQFNTQSTDISDAAPEIRYAQPDVNCLAAGQPPRLVHELNELSSNALKSF 756
            ..|...:...|.....|::....                           :|  |..|.::|.||
 Worm   678 AVIGHEITHGFDDQGSQYDKDGN---------------------------LH--NWWSESSLNSF 713

  Fly   757 HVTLSAARTAARAL-----------SNF-VNAIDAGSAIQGSGI-DQANTYEALGLTRRL----- 803
            .       |..|.:           :|| ||    |...||..| |.....||....::.
 Worm   714 D-------TRRRCIVEQYGNYTVPKTNFRVN----GKLTQGENIADNGGVKEAFQAYQKYVTENG 767

  Fly   804 ---RIPGLRSFNENELFTLSYMQQHC 826
               |:|||:.:...::|.:||....|
 Worm   768 EEPRLPGLQQYTNEQIFFVSYAHFWC 793

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
goe	NP_573160.1	GluZincin	184..>692	CDD:472708	111/548 (20%)
nep-11	NP_494538.1	M13	181..845	CDD:341056	142/706 (20%)