Protein Alignment ERAS and mrasb

DIOPT Version :9

• Sequence 1: NP_853510.1
• Gene: ERAS / 3266
• HGNCID: 5174
• Length: 233
• Species: Homo sapiens
• Sequence 2: XP_003201047.1
• Gene: mrasb / 100317924
• ZFINID: ZDB-GENE-050208-495
• Length: 209
• Species: Danio rerio
• Alignment Length: 198
• Identity: 78/198 - (39%)
• Similarity: 102/198 - (51%)
• Gaps: 5/198 - (2%)

Human    36 GRQLPEYKAVVVGASGVGKSALTIQLNHQCFVEDHDPTIQDSYWKELTLDSGDCILNVLDTAGQA 100
            |..||.||.||||..||||||||||...:.||.|:||||:|||.|...:|....||:|||||||.
Zfish     9 GDNLPVYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDGQWAILDVLDTAGQE 73

Human   101 IHRALRDQCLAVCDGVLGVFALDDPSS---LIQLQQIWATWGPHPAQPLVLVGNKCDLVTTAGDA 162
            ...|:|:|.:...||.|.||::.|.:|   :.:..|:........:.|:|||.||.|||......
Zfish    74 EFSAMREQYMRTGDGFLIVFSVTDKASFEHVDRFHQLILRVKDRESFPMVLVANKVDLVHLRKIT 138

Human   163 HAAAAALAHSWGAHFVETSAK-TRQGVEEAFSLLVHEI-QRVQEAMAKEPMARSCREKTRHQKAT 225
            ......:|......::||||| ....|::||..||..| |::.|...|:......|.........
Zfish   139 SEQGREMASKHSITYIETSAKDPPMNVDKAFHELVRVIRQQIPERGLKKKRKGKWRADRPSASQR 203

Human   226 CHC 228
            .||
Zfish   204 LHC 206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ERAS	NP_853510.1	RalA_RalB	42..201	CDD:206710	69/163 (42%)
		Effector region	70..78		5/7 (71%)
mrasb	XP_003201047.1	P-loop_NTPase	13..177	CDD:304359	69/163 (42%)
		small_GTPase	27..179	CDD:197466	60/151 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1259506at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920