DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4678 and SOL1

DIOPT Version :9

Sequence 1:	NP_001138211.1	Gene:	CG4678 / 32652	FlyBaseID:	FBgn0030778	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	NP_974126.1	Gene:	SOL1 / 843499	AraportID:	AT1G71696	Length:	491	Species:	Arabidopsis thaliana

Alignment Length:	464	Identity:	155/464 - (33%)
Similarity:	241/464 - (51%)	Gaps:	82/464 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 QLLLLPSVLLLMLHLLLC---DAKTVNPGDSMQMQH----HQMTAE---PGLPEPRAYMPDAQHL 68
            |.||:.:|:...|..:..   .:..::|||.....|    |....|   |.|...|.||
plant     8 QSLLISTVICFFLPSINARGGHSDHIHPGDGNYSFHGIVRHLFAQEEPTPSLELTRGYM------ 66

  Fly    69 DFVYHDHEELTRFLRATSARYPNLTALYSIGKSIQGRDLWVMVVSSSPYEHMVGKPDVKYVGNIH 133
                 .:::|.:.::..:.|...::.|||||||:.|..|||:.:|..|.| :..:|..||:||:|
plant    67 -----TNDDLEKAMKDFTKRCSKISRLYSIGKSVNGFPLWVIEISDRPGE-IEAEPAFKYIGNVH 125

  Fly   134 GNEPVGREMLLHLIQYFVTSYNTDQYVKWLLDNTRIHILPTMNPDGYAVSKEGTCDGGQGRYNAR 198
            |:||||||:||.|..:...:|..|...:.:::|..:||:|::||||:::.|         |.||.
plant   126 GDEPVGRELLLRLANWICDNYKKDPLAQMIVENVHLHIMPSLNPDGFSIRK---------RNNAN 181

  Fly   199 GFDLNRNFPDYFKQNN---KRGQPETDSVKDWISKIQFVLSGSLHGGALVASYPYDNTPNSRLLK 260
            ..||||:|||.|...|   ...||||.::..|:..|:|..|.:||||||||::|:|.|.:.|...
plant   182 NVDLNRDFPDQFFPFNDDLNLRQPETKAIMTWLRDIRFTASATLHGGALVANFPWDGTEDKRKYY 246

  Fly   261 GICRSSALCAMFQTYSAAPSLTPDDDVFKHLSLVYARNHAKMSRGVACKSATPAFENGITNGAAW 325
            ..|                   |||:.|:.|:.:|:::|..|       |.:..||.||||||:|
plant   247 YAC-------------------PDDETFRFLARIYSKSHRNM-------SLSKEFEEGITNGASW 285

  Fly   326 YPLTGGMQDYNYVWYGCMEITLEISCCKFPPAYELKKYWEDNQLSLIKFLAE-AHRGVQGFVFD- 388
            ||:.|||||:||::.||.|:|||||..|:|.|.||...|:.|:.|::..:|. ...||.|.:|.
plant   286 YPIYGGMQDWNYIYGGCFELTLEISDNKWPKASELSTIWDYNRKSMLNLVASLVKTGVHGRIFSL 350

  Fly   389 PAGMPIERASIKIKGRDVGFQTTK----YGEFWRILLPGY-YKVEVFAEGFAPR----------- 437
            ..|.|:. ..:.:||.:   .|.|    |.::.|:|:||. |:|...:.|:..:
plant   351 DKGKPLP-GLVVVKGIN---YTVKAHQTYADYHRLLVPGQKYEVTASSPGYKSKTTTVWLGENAV 411

  Fly   438 EVEFVIVEQ 446
            ..:|:::.:
plant   412 TADFILIPE 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4678	NP_001138211.1	M14_CP_N-E_like	72..377	CDD:199842	119/307 (39%)
CG4678	NP_001138211.1	Peptidase_M14NE-CP-C_like	381..455	CDD:200604	19/83 (23%)
SOL1	NP_974126.1	M14_CP_plant	65..337	CDD:349482	121/318 (38%)
SOL1	NP_974126.1	Peptidase_M14NE-CP-C_like	342..417	CDD:200604	19/78 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	228	1.000	Domainoid score	I664
eggNOG	1	0.900	-	-		E1_KOG2649
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	248	1.000	Inparanoid score	I1040
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D101221at2759
OrthoFinder	1	1.000	-	-		FOG0000769
OrthoInspector	1	1.000	-	-		otm3347
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11532
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.930