DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4678 and cpda

DIOPT Version :9

Sequence 1:	NP_001138211.1	Gene:	CG4678 / 32652	FlyBaseID:	FBgn0030778	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	XP_005157676.1	Gene:	cpda / 563008	ZFINID:	ZDB-GENE-081112-2	Length:	1350	Species:	Danio rerio

Alignment Length:	394	Identity:	170/394 - (43%)
Similarity:	254/394 - (64%)	Gaps:	23/394 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 QHLDFVYHDHEELTRFLRATSARYPNLTALYSIGKSIQGRDLWVMVVSSSPYEHMVGKPDVKYVG 130
            |..:|.:|.:.::..|::..|:.|.::|.|||||||:|.|.||||.:|::|..|.:|:|:.||:|
Zfish   468 QPQEFRHHRYIDMELFMKKFSSEYSSITRLYSIGKSVQKRLLWVMEISNNPGVHELGEPEFKYIG 532

  Fly   131 NIHGNEPVGREMLLHLIQYFVTSYNTDQYVKWLLDNTRIHILPTMNPDGYAVSKEGTCDGGQGRY 195
            |:||||.||||:||:||:|...:|.||..|..|:|.|||||:|:||||||.||::|..:|.:||.
Zfish   533 NMHGNEVVGRELLLNLIEYLCRNYGTDPEVTQLVDTTRIHIMPSMNPDGYEVSQKGDVEGIKGRN 597

  Fly   196 NARGFDLNRNFPDYFKQNNKRGQPETDSVKDWISKIQFVLSGSLHGGALVASYPYDNTPNSRLLK 260
            |::.:||||||||.||......||||.:|.:|.....||||.:||||:||.:||:|:  |...:.
Zfish   598 NSKNYDLNRNFPDRFKLITDPIQPETLAVMNWSKNYSFVLSANLHGGSLVVNYPFDD--NLEDVI 660

  Fly   261 GICRSSALCAMFQTYSAAPSLTPDDDVFKHLSLVYARNHAKMSRGVACK--SATPA-FENGITNG 322
            |..:|                 |||.||:.::|.|::.:::|..|..||  |:.|. |::|||||
Zfish   661 GYSKS-----------------PDDAVFRMVALAYSQENSEMHEGHPCKEMSSYPEYFQDGITNG 708

  Fly   323 AAWYPLTGGMQDYNYVWYGCMEITLEISCCKFPPAYELKKYWEDNQLSLIKFLAEAHRGVQGFVF 387
            ||||.:.|||||:||:...|.|:|:|:.|.|:||..:|:||||.|:.||::|:.:.||||:|.|.
Zfish   709 AAWYNVHGGMQDWNYMNTNCFEVTIELGCHKYPPVADLQKYWEQNRKSLLQFIHQVHRGVKGMVI 773

  Fly   388 DPA-GMPIERASIKIKGRDVGFQTTKYGEFWRILLPGYYKVEVFAEGFAPREVEFVIVEQHPTLL 451
            |.. |..|..|:|.::.......::..|::||:|:||.||:...|:|:........:.:....::
Zfish   774 DSKDGSGIPNATITVETIHHQVTSSSLGDYWRLLVPGKYKLTASAQGYMSDSSSVTVPKDGLEIV 838

  Fly   452 NVTL 455
            |.||
Zfish   839 NFTL 842

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4678	NP_001138211.1	M14_CP_N-E_like	72..377	CDD:199842	144/307 (47%)
CG4678	NP_001138211.1	Peptidase_M14NE-CP-C_like	381..455	CDD:200604	20/74 (27%)
cpda	XP_005157676.1	M14_CPD_I	46..340	CDD:199850
		Peptidase_M14NE-CP-C_like	344..420	CDD:200604
		M14_CPD_II	467..763	CDD:199845	146/313 (47%)
		Peptidase_M14NE-CP-C_like	767..842	CDD:200604	20/74 (27%)
		Peptidase_M14_like	895..1179	CDD:325013
		Peptidase_M14NE-CP-C_like	1183..1259	CDD:200604
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2649
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D101221at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3496
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.850