DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4678 and cpn1

DIOPT Version :9

Sequence 1:	NP_001138211.1	Gene:	CG4678 / 32652	FlyBaseID:	FBgn0030778	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	NP_001017266.1	Gene:	cpn1 / 550020	XenbaseID:	XB-GENE-967670	Length:	449	Species:	Xenopus tropicalis

Alignment Length:	422	Identity:	169/422 - (40%)
Similarity:	241/422 - (57%)	Gaps:	47/422 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 AQHLDFVYHDHEELTRFLRATSARYPNLTALYSIGKSIQGRDLWVMVVSSSPYEHMVGKPDVKYV 129
            |..|.|.:|.:::|.|.|.....:.|.:|.:||||:|:|||.|:|:..|.:|..|.:.:|:.|||
Frog    18 AASLSFFHHRYDDLVRALYNVQNQCPYITRVYSIGRSVQGRHLYVIEFSDNPGIHELLEPEFKYV 82

  Fly   130 GNIHGNEPVGREMLLHLIQYFVTSY-NTDQYVKWLLDNTRIHILPTMNPDGYAVSKEGTCDGG-- 191
            ||:||||.:|||:|:.|.::....| |.::.|..|:..|||||||:||||||.|:.:...:|.
Frog    83 GNMHGNEVLGRELLIQLAEFLCEEYRNNNERVTRLIQTTRIHILPSMNPDGYEVAADQGPEGNGY 147

  Fly   192 -QGRYNARGFDLNRNFPD-----YFKQNNKRG----------------QPETDSVKDWISKIQFV 234
             .||||.|..||||||||     |:  |.|.|                :|||.::..|:....||
Frog   148 LTGRYNYRQVDLNRNFPDLNTVMYY--NEKYGGPNHHLPLPDNWMAQVEPETQAMIQWLKNYNFV 210

  Fly   235 LSGSLHGGALVASYPYDNTPNSRLLKGICRSSALCAMFQTYSAAPSLTPDDDVFKHLSLVYARNH 299
            ||.:|||||:||:||||.:...| ::|..||        |||:    ||||.:||.|:..|:..|
Frog   211 LSANLHGGAVVANYPYDKSKEIR-MRGFTRS--------TYSS----TPDDALFKELAKTYSYAH 262

  Fly   300 AKMSRGVACKSATPAFENGITNGAAWYPLTGGMQDYNYVWYGCMEITLEISCCKFPPAYELKKYW 364
            ..|..|..|..   .|..||||||:||.|..||||:||:...|.|||||:||.|||...||::.|
Frog   263 GWMHTGYNCDD---FFYEGITNGASWYSLYKGMQDFNYLHTNCFEITLELSCDKFPREEELEQEW 324

  Fly   365 EDNQLSLIKFLAEAHRGVQGFVFDPAGMPIERASIKIKGRDVGFQTTK--YGEFWRILLPGYYKV 427
            ..|:.:|:.::.:.|:|::|.:.|..|..|..|.|.|.  ::....|.  .|:::|:||||.|:|
Frog   325 NGNREALLTYIDKVHQGIKGMITDENGNGIANAVISIS--EIAHDVTSGIGGDYFRLLLPGTYEV 387

  Fly   428 EVFAEGFAPREVEFVIVEQHPTLLNVTLQPSK 459
            ...|||:..:.|...:.....||::..|:..|
Frog   388 TASAEGYYFKTVSATVGPADATLVHFQLKQQK 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4678	NP_001138211.1	M14_CP_N-E_like	72..377	CDD:199842	140/329 (43%)
CG4678	NP_001138211.1	Peptidase_M14NE-CP-C_like	381..455	CDD:200604	23/75 (31%)
cpn1	NP_001017266.1	Peptidase_M14_like	25..337	CDD:386095	140/329 (43%)
cpn1	NP_001017266.1	Peptidase_M14NE-CP-C_like	341..415	CDD:200604	23/75 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	51	1.000	Domainoid score	I11366
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D101221at2759
OrthoFinder	1	1.000	-	-		FOG0000769
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010