DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4678 and Cpxm1

DIOPT Version :9

Sequence 1:	NP_001138211.1	Gene:	CG4678 / 32652	FlyBaseID:	FBgn0030778	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	NP_001099981.1	Gene:	Cpxm1 / 296156	RGDID:	1306937	Length:	722	Species:	Rattus norvegicus

Alignment Length:	450	Identity:	162/450 - (36%)
Similarity:	234/450 - (52%)	Gaps:	64/450 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 EPRAYMPDA------QHLDFVYHDHEELTRFLRATSARYPNLTALYSIGKSIQGRDLWVMVVSSS 115
            :|....|:|      ..|||.:|:::.:.:.::..:.:.||:|.:||||||.||..|:||.:|..
  Rat   267 DPNDLFPEAHTLGSSDSLDFRHHNYKAMRKLMKEVNEQCPNITRIYSIGKSHQGLKLYVMEMSDH 331

  Fly   116 PYEHMVGKPDVKYVGNIHGNEPVGREMLLHLIQYFVTSY-NTDQYVKWLLDNTRIHILPTMNPDG 179
            |.||.:|:|:|:||..:||||.:|||:||.|:|:....: ..|..|..||..||||:||:|||||
  Rat   332 PGEHELGEPEVRYVAGMHGNEALGRELLLLLMQFLCREFLRGDPRVTRLLTETRIHLLPSMNPDG 396

  Fly   180 Y--AVSKEGTCDG-GQGRYNARGFDLNRNF---------------------------PDYFKQNN 214
            |  |..|.....| .:||:..:|.|||.||                           |.|:...|
  Rat   397 YETAYHKGSELVGWAEGRWTHQGIDLNHNFADLNTQLWYAEDDGLVPHTVPNHHLPLPTYYTLPN 461

  Fly   215 KRGQPETDSVKDWISKIQFVLSGSLHGGALVASYPYDNTPNSRLLKGICRSSALCAMFQTYSAAP 279
            ....|||.:|..|:.:|.||||.:||||.||.|||:|                   |.:|..||.
  Rat   462 ATVAPETWAVIKWMKRIPFVLSANLHGGELVVSYPFD-------------------MTRTPWAAR 507

  Fly   280 SL--TPDDDVFKHLSLVYARNHAKM--SRGVACKSATPAFENGITNGAAWYPLTGGMQDYNYVWY 340
            .|  ||||.||:.||.|||..:..|  :....|.|...:....:.|||.|:.:.|.|.|::|:..
  Rat   508 ELTPTPDDAVFRWLSTVYAGTNRAMQDTDRRPCHSQDFSLHGNVINGADWHTVPGSMNDFSYLHT 572

  Fly   341 GCMEITLEISCCKFPPAYELKKYWEDNQLSLIKFLAEAHRGVQGFVFD-PAGMPIERASIKIKGR 404
            .|.|:|:|:||.|||...||.:.||:|:.:|:.:|.:...|:.|.|.| ...:.|..|.|.::|.
  Rat   573 NCFEVTVELSCDKFPHEKELPQEWENNKDALLTYLEQVRMGITGVVRDKDTELGIADAVIAVEGI 637

  Fly   405 DVGFQTTKYGEFWRILLPGYYKVEVFAEGF-APREVEFVIVEQHPTLLN--VTLQPSKRL 461
            :....|...|::||:|.||.|.|...|||: ..::...|..|:.|...|  :|..|.:||
  Rat   638 NHDVTTAWGGDYWRLLTPGDYVVTASAEGYHTAKQHCRVTFEEGPVPCNFLLTKTPKQRL 697

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4678	NP_001138211.1	M14_CP_N-E_like	72..377	CDD:199842	128/339 (38%)
CG4678	NP_001138211.1	Peptidase_M14NE-CP-C_like	381..455	CDD:200604	24/77 (31%)
Cpxm1	NP_001099981.1	FA58C	106..262	CDD:238014
		FA58C	107..263	CDD:214572
		M14_CPX_like	284..609	CDD:199851	131/343 (38%)
		Peptidase_M14NE-CP-C_like	613..689	CDD:200604	24/75 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2649
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D101221at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820