| Sequence 1: | NP_001138211.1 | Gene: | CG4678 / 32652 | FlyBaseID: | FBgn0030778 | Length: | 527 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001120.3 | Gene: | AEBP1 / 165 | HGNCID: | 303 | Length: | 1158 | Species: | Homo sapiens |
| Alignment Length: | 519 | Identity: | 165/519 - (31%) |
|---|---|---|---|
| Similarity: | 255/519 - (49%) | Gaps: | 78/519 - (15%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 22 LLLMLHLLLCDAKTVNPGDSMQMQHHQMTAEPGLPEPRAYMPDAQHLDFVYHDHEELTRFLRATS 86
Fly 87 ARYPNLTALYSIGKSIQGRDLWVMVVSSSPYEHMVGKPDVKYVGNIHGNEPVGREMLLHLIQYFV 151
Fly 152 TSY-NTDQYVKWLLDNTRIHILPTMNPDGYAVSKEGTCDGGQ---GRYNARGFDLNRNFPD---- 208
Fly 209 -----------YFKQNNKRGQP------------ETDSVKDWISKIQFVLSGSLHGGALVASYPY 250
Fly 251 D--NTPNSRLLKGICRSSALCAMFQTYSAAPSLTPDDDVFKHLSLVYARNHAKMS---RGVACKS 310
Fly 311 ATPAFENGITNGAAWYPLTGGMQDYNYVWYGCMEITLEISCCKFPPAYELKKYWEDNQLSLIKFL 375
Fly 376 AEAHRGVQGFVFDPAGMPIERASIKIKGRDVGFQTTKYGEFWRILLPGYYKVEVFAEGFAPR--- 437
Fly 438 -EVEFVIVEQHPTLLNVTLQPS--KRLEGIGPMGPGGVPVGGVVGPGGLYRPIPSPQHYRPPVP 498 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CG4678 | NP_001138211.1 | M14_CP_N-E_like | 72..377 | CDD:199842 | 110/340 (32%) |
| Peptidase_M14NE-CP-C_like | 381..455 | CDD:200604 | 29/77 (38%) | ||
| AEBP1 | NP_001120.3 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 40..387 | ||
| FA58C | 384..540 | CDD:214572 | 3/8 (38%) | ||
| FA58C | 386..539 | CDD:238014 | 2/7 (29%) | ||
| Required for DNA-binding and interaction with NFKBIA. /evidence=ECO:0000250 | 390..555 | 8/26 (31%) | |||
| Interaction with MAPK1 and MAPK3. /evidence=ECO:0000250 | 421..624 | 28/109 (26%) | |||
| Interaction with PTEN. /evidence=ECO:0000250 | 555..985 | 145/448 (32%) | |||
| M14_CPX_like | 560..903 | CDD:199851 | 113/344 (33%) | ||
| Peptidase_M14NE-CP-C_like | 907..982 | CDD:200604 | 29/77 (38%) | ||
| Required for transcriptional repression. /evidence=ECO:0000250 | 941..1158 | 29/90 (32%) | |||
| Interaction with MAPK1 and MAPK3. /evidence=ECO:0000250 | 1006..1158 | 3/8 (38%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1108..1141 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG2649 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D101221at2759 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.820 | |||||