DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4678 and aebp1

DIOPT Version :9

Sequence 1:	NP_001138211.1	Gene:	CG4678 / 32652	FlyBaseID:	FBgn0030778	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	XP_031755150.1	Gene:	aebp1 / 100487826	XenbaseID:	XB-GENE-6462732	Length:	1222	Species:	Xenopus tropicalis

Alignment Length:	484	Identity:	148/484 - (30%)
Similarity:	235/484 - (48%)	Gaps:	88/484 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 PDAQHLDFVYHDHEELTRFLRATSARYPNLTALYSIGKSIQGRDLWVMVVSSSPYEHMVGKPDVK 127
            ||  :|||.:|::::|.:.::..:...|.:|.:|:|||:.:|..::.|.:|.:|.:|..|:|:.:
Frog   643 PD--NLDFRHHNYKDLRQLMKVVNDECPTITRIYNIGKTPKGLKIYAMEISDNPGDHETGEPEFR 705

  Fly   128 YVGNIHGNEPVGREMLLHLIQYFVTSY-NTDQYVKWLLDNTRIHILPTMNPDGYAVSKEGTCDGG 191
            |...:||||.:||||||.|:|:....: :.:..:..|:.:||||::|::|||||.::.:...:.|
Frog   706 YTAGLHGNEVLGREMLLLLMQFICKEFRDGNPRITSLVRDTRIHLVPSLNPDGYEIASQMGSELG 770

  Fly   192 Q---GRYNARGFDLNRNFPDY---------------------------FKQNNKRGQPETDSVKD 226
            .   |.:...|:|:..||||.                           |...:.....||.::..
Frog   771 NWALGHWTEEGYDIFTNFPDLNTVLWGAEERKWVPHRVPNHHLPIPDSFMAEDATVAMETKAIIA 835

  Fly   227 WISKIQFVLSGSLHGGALVASYPYD-------NTPNSRLLKGICRSSALCAMFQTY--------- 275
            |:.||.|||..:|.||..:.|||||       ..|..|            ..:|.|
Frog   836 WMEKIPFVLGANLQGGEKLISYPYDMARPVKEEAPPER------------PQYQRYHQEEEEEEE 888

  Fly   276 ----------SAAPSLTPDDDVFKHLSLVYARNHAKM---SRGVACKSATPAFENGITNGAAWYP 327
                      ....|.|||..:|:.|::.|:..|..|   :|| :|.:.......||.|||.|.|
Frog   889 DQFVEVEAEDEEGVSRTPDHSIFRWLAISYSSAHLTMGETARG-SCHADDFTKGMGIANGAKWRP 952

  Fly   328 LTGGMQDYNYVWYGCMEITLEISCCKFPPAYELKKYWEDNQLSLIKFLAEAHRGVQGFVFDPAGM 392
            .:|.|.|::|:...|:|:::.:.|.|:|...||.:.||:|:.||:.|:.:.|||::|.|.|..|.
Frog   953 QSGTMNDFSYLHTNCLEMSIYLGCDKYPHETELAEEWENNKESLLSFMEQVHRGIKGIVTDREGE 1017

  Fly   393 PIERASIKIKGRDVGFQTTKYGEFWRILLPGYYKVEVFAEGFAPR----EVEFVIVEQHPTLLNV 453
            ||..|:|.|...:...:|...|::||||.||.|:|...|||:...    .|.:.|...|   .|.
Frog  1018 PIANATISIGEINHDIKTASTGDYWRILNPGEYRVTARAEGYTQGTKTCSVGYDIGATH---CNF 1079

  Fly   454 TLQPS--KRLEGIGPMGPGG----VPVGG 476
            .|..|  ||::.|..|...|    .|.||
Frog  1080 VLARSNWKRIKEIIAMKGNGRLQLAPPGG 1108

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4678	NP_001138211.1	M14_CP_N-E_like	72..377	CDD:199842	104/364 (29%)
CG4678	NP_001138211.1	Peptidase_M14NE-CP-C_like	381..455	CDD:200604	27/77 (35%)
aebp1	XP_031755150.1	DUF5401	<201..>302	CDD:375164
		FA58C	471..624	CDD:238014
		Peptidase_M14_like	650..1002	CDD:416253	104/364 (29%)
		Peptidase_M14NE-CP-C_like	1006..1081	CDD:200604	27/77 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D101221at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010