DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4678 and cpxm1

DIOPT Version :9

Sequence 1:	NP_001138211.1	Gene:	CG4678 / 32652	FlyBaseID:	FBgn0030778	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	XP_002936314.2	Gene:	cpxm1 / 100487254	XenbaseID:	XB-GENE-977808	Length:	743	Species:	Xenopus tropicalis

Alignment Length:	496	Identity:	169/496 - (34%)
Similarity:	254/496 - (51%)	Gaps:	81/496 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LRTPLVAGH---QLQLLLLPSVLLLMLHLLLCDAKTVNPGDSMQMQHHQMTAEPGLPEPRAYMPD 64
            |.||:|..:   ..|.......:.|...:|.|...  :|......:|        :|||
Frog   246 LPTPMVGRYIRINPQTWFENGTICLRAEILGCPLP--DPNTVFMWEH--------VPEP------ 294

  Fly    65 AQHLDFVYHDHEELTRFLRATSARYPNLTALYSIGKSIQGRDLWVMVVSSSPYEHMVGKPDVKYV 129
            ...|||.:|:::|:.:.::|.:...|.:|.:||||||..|..::||.:|.:|.:|.:|:|:.:||
Frog   295 TDKLDFKHHNYKEMRKLMKAVNDECPEITRVYSIGKSYLGLKMYVMEISDNPGQHELGEPEFRYV 359

  Fly   130 GNIHGNEPVGREMLLHLIQYFVTSYNT-DQYVKWLLDNTRIHILPTMNPDGYAVS-KEGTCDGG- 191
            ..:||||.||||::|:|:||....|.. :..|..|:..||||:||:||||||..: |.|:...|
Frog   360 AGMHGNEVVGRELMLNLMQYLCMEYKKGNPRVMRLVTETRIHLLPSMNPDGYEQAYKLGSELSGW 424

  Fly   192 -QGRYNARGFDLNRNF---------------------------PDYFKQNNKRGQPETDSVKDWI 228
             .||:..:|||||.||                           |:|:...|....|||.:|.||:
Frog   425 AYGRWTYQGFDLNHNFADLNTPLWEAEDNEEVPHKFPNHYIPIPEYYTFANATVTPETRAVIDWM 489

  Fly   229 SKIQFVLSGSLHGGALVASYPYDNTPNSRLLKGICRSSALCAMFQTYSAAPSL--TPDDDVFKHL 291
            .||.||||.::|||.||.:||:|                   |.::|..|..|  ||||.:|:.|
Frog   490 QKIPFVLSANMHGGELVVTYPFD-------------------MTRSYWMAKELTPTPDDAMFRWL 535

  Fly   292 SLVYARNHAKM---SRGVACKSATPAFENGITNGAAWYPLTGGMQDYNYVWYGCMEITLEISCCK 353
            :.|||.::..|   :|.: |.:.....:..|.|||.|:.:.|.|.|::|:...|.|:|:|:||.|
Frog   536 ATVYATSNRVMADDNRRI-CHTENFMRQGNIINGADWHTVAGSMNDFSYLHTNCFEVTVELSCDK 599

  Fly   354 FPPAYELKKYWEDNQLSLIKFLAEAHRGVQGFVFD---PAGMPIERASIKIKGRDVGFQTTKYGE 415
            ||...||...||:|:.||:.|:.:.|||::|.|.|   ..|:|  .|.|.:...:...:|...|:
Frog   600 FPHEVELPVEWENNKESLLVFMEQVHRGIKGVVRDKDTEKGIP--EAIIVVNELNHDIRTAVDGD 662

  Fly   416 FWRILLPGYYKVEVFAEGFAPREVEF-VIVEQHPTLLNVTL 455
            :||:|.||.|:|...|||:.|..... |..|.|.|:.:..|
Frog   663 YWRLLNPGEYEVTAKAEGYHPSTKSCRVTYENHATICDFYL 703

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4678	NP_001138211.1	M14_CP_N-E_like	72..377	CDD:199842	125/340 (37%)
CG4678	NP_001138211.1	Peptidase_M14NE-CP-C_like	381..455	CDD:200604	25/77 (32%)
cpxm1	XP_002936314.2	FA58C	121..276	CDD:238014	6/29 (21%)
		M14_CPX_like	302..623	CDD:349441	125/340 (37%)
		Peptidase_M14NE-CP-C_like	627..703	CDD:200604	25/77 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D101221at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920