DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4678 and cpd

DIOPT Version :9

Sequence 1:	NP_001138211.1	Gene:	CG4678 / 32652	FlyBaseID:	FBgn0030778	Length:	527	Species:	Drosophila melanogaster
Sequence 2:	XP_031752525.1	Gene:	cpd / 100135269	XenbaseID:	XB-GENE-1013552	Length:	1339	Species:	Xenopus tropicalis

Alignment Length:	413	Identity:	179/413 - (43%)
Similarity:	250/413 - (60%)	Gaps:	34/413 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 QMTAEPGLPEPRAYMPDAQHLDFVYHDHEELTRFLRATSARYPNLTALYSIGKSIQGRDLWVMVV 112
            |.|..|.:    |..|.    ||.:|.:.::..||....:.||::|..||:|||::.:||:||.:
Frog   444 QSTTTPRI----AIQPQ----DFRHHRYTDMEIFLMKFHSEYPSITRRYSVGKSVEQKDLYVMEI 500

  Fly   113 SSSPYEHMVGKPDVKYVGNIHGNEPVGREMLLHLIQYFVTSYNTDQYVKWLLDNTRIHILPTMNP 177
            |.:|..|..|:|:.||:||:||||.||||:||:||:|...:|..|..|.:|:.||||||:|:|||
Frog   501 SDNPGIHEPGEPEFKYIGNMHGNEVVGRELLLNLIEYLCKNYGIDPEVTYLVQNTRIHIMPSMNP 565

  Fly   178 DGYAVSKEGTCDGGQGRYNARGFDLNRNFPDYFKQNNKRGQPETDSVKDWISKIQFVLSGSLHGG 242
            |||..::||..||..||.|:..|||||||||.|.|.....||||.:|..|:....||||.:||||
Frog   566 DGYEKAEEGDKDGLVGRNNSNHFDLNRNFPDQFFQITDPPQPETLAVMTWLKTYPFVLSANLHGG 630

  Fly   243 ALVASYPYDNTPNSRLLKGICRSSALCAMFQTYSAAPSLTPDDDVFKHLSLVYARNHAKMSRGVA 307
            :||.:||:|:..     ||:          .|||.    :|||.||:||:|.|::.:.||..|..
Frog   631 SLVVNYPFDDDE-----KGL----------STYSK----SPDDPVFQHLALSYSKENNKMYEGFP 676

  Fly   308 CKSATP--AFENGITNGAAWYPLTGGMQDYNYVWYGCMEITLEISCCKFPPAYELKKYWEDNQLS 370
            ||...|  .|..||||||.||.:.|||||:||:...|.|:|:|:.|.|:|.|.:|..|||.|:.|
Frog   677 CKEMYPNENFPQGITNGANWYNVPGGMQDWNYLNTNCFEVTIELGCVKYPMAEKLPAYWESNRRS 741

  Fly   371 LIKFLAEAHRGVQGFVFDPA-GMPIERASIKIKGRDVGFQTTKY--GEFWRILLPGYYKVEVFAE 432
            :::|:.:.|.|::||:.|.. |..|..|:|.:.|  :....|.|  |:|||:|:||.|||...|:
Frog   742 MLQFIKQVHIGIKGFILDATDGRGILNATISVAG--INHMVTSYKDGDFWRLLVPGAYKVTASAK 804

  Fly   433 GFAPREVEFVIVEQHPTLLNVTL 455
            |:.|......:.|....|:|.||
Frog   805 GYGPVTKNVNVTEGEAVLVNFTL 827

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4678	NP_001138211.1	M14_CP_N-E_like	72..377	CDD:199842	142/306 (46%)
CG4678	NP_001138211.1	Peptidase_M14NE-CP-C_like	381..455	CDD:200604	27/76 (36%)
cpd	XP_031752525.1	M14_CPD_I	39..333	CDD:349440
		Peptidase_M14NE-CP-C_like	337..413	CDD:200604
		M14_CPD_II	453..748	CDD:349435	145/317 (46%)
		Peptidase_M14NE-CP-C_like	752..827	CDD:200604	27/76 (36%)
		M14_CPD_III	886..1169	CDD:349464
		Peptidase_M14NE-CP-C_like	1173..1248	CDD:200604
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	51	1.000	Domainoid score	I11366
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D101221at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010