DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9672 and PRSS1

DIOPT Version :9

Sequence 1:	NP_573151.1	Gene:	CG9672 / 32651	FlyBaseID:	FBgn0030777	Length:	253	Species:	Drosophila melanogaster
Sequence 2:	XP_011514713.1	Gene:	PRSS1 / 5644	HGNCID:	9475	Length:	472	Species:	Homo sapiens

Alignment Length:	224	Identity:	61/224 - (27%)
Similarity:	99/224 - (44%)	Gaps:	26/224 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LILVAAGVLEAQP---QGRIAGGEDAVLGQLPYQAALSIGGSYNCGAVIIGQRYALTALSCVCSD 70
            |||.......|.|   ..:|.||.:.....:|||.:|: .|.:.||..:|.:::.::|..|..|
Human   230 LILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLN-SGYHFCGGSLINEQWVVSAGHCYKS- 292

  Fly    71 GKDTPWAAVLFAVTVG--SVDLYNGKQ--IRVEEITINPNY--STLKTGIALLRLQEEITFSETV 129
                     ...|.:|  ::::..|.:  |...:|..:|.|  .||...|.|::|......:..|
Human   293 ---------RIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARV 348

  Fly   130 NAIPLSQDVPPMGSQVEVSGWGRTTESEVNMHRTLQIGAAEVMAPRECALANRDELLVADDQVLC 194
            :.|.|....|..|::..:||||.|..|..:....||...|.|::..:|..:...::   ...:.|
Human   349 STISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKI---TSNMFC 410

  Fly   195 LG--HGRRQGICSGDIGGPAVYQGQLVGL 221
            :|  .|.:.. |.||.|||.|..|||.|:
Human   411 VGFLEGGKDS-CQGDSGGPVVCNGQLQGV 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9672	NP_573151.1	Tryp_SPc	24..247	CDD:214473	56/206 (27%)
CG9672	NP_573151.1	Tryp_SPc	25..250	CDD:238113	56/205 (27%)
PRSS1	XP_011514713.1	Ig	19..119	CDD:299845
		IG_like	29..113	CDD:214653
		Tryp_SPc	248..464	CDD:214473	56/206 (27%)
		Tryp_SPc	249..467	CDD:238113	56/205 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D469244at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920