DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG9672 and KLK12

DIOPT Version :9

Sequence 1:NP_573151.1 Gene:CG9672 / 32651 FlyBaseID:FBgn0030777 Length:253 Species:Drosophila melanogaster
Sequence 2:NP_062544.1 Gene:KLK12 / 43849 HGNCID:6360 Length:254 Species:Homo sapiens


Alignment Length:237 Identity:67/237 - (28%)
Similarity:99/237 - (41%) Gaps:27/237 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 LTIGLILVAAGVLEAQPQGRIAGGEDAVLGQLPYQAALSIGGSYNCGAVIIGQRYALTALSCVCS 69
            |:|.|:|...|:.:|... :|..|.:......|:|..|..|.|..||.|:|..|:.|||..|   
Human     3 LSIFLLLCVLGLSQAATP-KIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAHC--- 63

  Fly    70 DGKDTPWAAVLFAVTVGSVDLYN---GKQIRVEEITI-NPNYSTLKTG----IALLRLQEEITFS 126
                   :...:.|.:|...|..   .:|||....:: :|.|....|.    :.||||:..:..:
Human    64 -------SGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRVT 121

  Fly   127 ETVNAIPLSQDVPPMGSQVEVSGWGRTTESEVNMHRTLQIGAAEVMAPRECALANRDELLVADDQ 191
            .:|..:||..|....|::..|||||.|..........||.....:::...|.......:   ...
Human   122 SSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRI---TSN 183

  Fly   192 VLCLGHGRRQGICSGDIGGPAVYQGQLVGL---GAQILGECG 230
            ::|.|....|..|.||.|||.|..|.|.||   |:  :|.||
Human   184 MVCAGGVPGQDACQGDSGGPLVCGGVLQGLVSWGS--VGPCG 223

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG9672NP_573151.1 Tryp_SPc 24..247 CDD:214473 61/218 (28%)
Tryp_SPc 25..250 CDD:238113 61/217 (28%)
KLK12NP_062544.1 Tryp_SPc 21..236 CDD:214473 61/218 (28%)
Tryp_SPc 22..236 CDD:238113 61/217 (28%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D469244at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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