Protein Alignment CG4653 and TMPRSS13

DIOPT Version :10

• Sequence 1: NP_573150.2
• Gene: CG4653 / 32650
• FlyBaseID: FBgn0030776
• Length: 254
• Species: Drosophila melanogaster
• Sequence 2: NP_001070731.1
• Gene: TMPRSS13 / 84000
• HGNCID: 29808
• Length: 567
• Species: Homo sapiens
• Alignment Length: 271
• Identity: 73/271 - (26%)
• Similarity: 114/271 - (42%)
• Gaps: 45/271 - (16%)

  Fly     3 PVQSY-----SHSRLLLLVVIVTLGVVQSSRLPAEVGSQPHSISLRRNGVHVCGGALIREKWILT 62
            |.|.|     ||..|..:...:..|.:.|.      ...|..:||.....|:|||.||..:|:||
Human   305 PSQRYISLQCSHCGLRAMTGRIVGGALASD------SKWPWQVSLHFGTTHICGGTLIDAQWVLT 363

  Fly    63 AAHCVSLGGGQQSYPAKSYNVRVGSIQRLTGGQLVPLSKIIIHTNYSSSDAVGSNDLALLELETS 127
            ||||..:   .:....:.:.|..|:.......:...:::|||::||  :|.....|:||:.|...
Human   364 AAHCFFV---TREKVLEGWKVYAGTSNLHQLPEAASIAEIIINSNY--TDEEDDYDIALMRLSKP 423

  Fly   128 VVLNANTNPIDLATERPAAGSQII------FSGWGSS-QVDGSLSHVLQVATRQSLSASDCQTEL 185
            :.|:|:.:|..|    |..|....      .:|:|.: :.|...|..|:......:....|...|
Human   424 LTLSAHIHPACL----PMHGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYL 484

  Fly   186 ----YLQQEDLLCLSPVDEDFAG---LCSGDAGAP--ASYNNQ--LVGIAAFFVSGCGS-EQPDG 238
                ||... ::|..    |..|   .|.||:|.|  ...||:  |.|:.: :.:|||. .:|..
Human   485 VYDSYLTPR-MMCAG----DLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTS-WGTGCGQRNKPGV 543

  Fly   239 YVDVTQHLEWI 249
            |..||:.|.||
Human   544 YTKVTEVLPWI 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4653	NP_573150.2	Tryp_SPc	30..252	CDD:238113	65/239 (27%)
TMPRSS13	NP_001070731.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..115
		PHA03378	<9..148	CDD:223065
		13 X 5 AA repeats of A-S-P-A-[GLQR]	9..93
		4 X 5 AA repeats of T-P-P-G-R	14..68
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	131..157
		SRCR_2	231..321	CDD:464747	6/15 (40%)
		Tryp_SPc	325..554	CDD:214473	65/249 (26%)