Protein Alignment CG4653 and PRSS27

DIOPT Version :10

• Sequence 1: NP_573150.2
• Gene: CG4653 / 32650
• FlyBaseID: FBgn0030776
• Length: 254
• Species: Drosophila melanogaster
• Sequence 2: NP_114154.1
• Gene: PRSS27 / 83886
• HGNCID: 15475
• Length: 290
• Species: Homo sapiens
• Alignment Length: 250
• Identity: 75/250 - (30%)
• Similarity: 106/250 - (42%)
• Gaps: 53/250 - (21%)

  Fly    34 GSQPHSISLRRNGVHVCGGALIREKWILTAAHCVSLGGGQQSYPAKSYNVRVGSIQRLTGGQLVP 98
            |..|..:|::|||.|.|||:||.|:|:||||||.     :.:.....|.|.:|:.|.:..|.
Human    44 GEWPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCF-----RNTSETSLYQVLLGARQLVQPGP--- 100

  Fly    99 LSKIIIHTNYSSSDAVGSN----------DLALLELETSVVLNANTNPIDLATERPA----AGSQ 149
                  |..|:....|.||          |:||:|||..|.......|:.|..  |:    .|..
Human   101 ------HAMYARVRQVESNPLYQGTASSADVALVELEAPVPFTNYILPVCLPD--PSVIFETGMN 157

  Fly   150 IIFSGWGSSQVDGSL--SHVLQVATRQSLSASDC------QTELYLQ----QEDLLCLSPVDEDF 202
            ...:||||...:..|  ..:||......:....|      .||...|    :.|:|| :..:|..
Human   158 CWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGYQPKTIKNDMLC-AGFEEGK 221

  Fly   203 AGLCSGDAGAPASYNNQLVG---IAAFFVS---GCGSE-QPDGYVDVTQHLEWIN 250
            ...|.||:|.|...   |||   :.|..:|   ||..: :|..|:.||.|..||:
Human   222 KDACKGDSGGPLVC---LVGQSWLQAGVISWGEGCARQNRPGVYIRVTAHHNWIH 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4653	NP_573150.2	Tryp_SPc	30..252	CDD:238113	75/249 (30%)
PRSS27	NP_114154.1	Tryp_SPc	36..275	CDD:238113	75/249 (30%)