DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4653 and prss60.1

DIOPT Version :9

Sequence 1:	NP_573150.2	Gene:	CG4653 / 32650	FlyBaseID:	FBgn0030776	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	NP_001082915.1	Gene:	prss60.1 / 799770	ZFINID:	ZDB-GENE-070424-25	Length:	387	Species:	Danio rerio

Alignment Length:	246	Identity:	71/246 - (28%)
Similarity:	101/246 - (41%)	Gaps:	52/246 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 GSQPHSISLRR--NGVHVCGGALIREKWILTAAHC----------VSLGGGQQSYPAKSYNVRVG 86
            ||.|..:||..  .|.|.|||:||..:|:||||||          |.||...|.      .|...
Zfish    43 GSWPWQVSLHSPIYGGHFCGGSLINSEWVLTAAHCLPRITTSSLLVFLGKTTQQ------GVNTY 101

  Fly    87 SIQRLTGGQLVPLSKIIIHTNYSSSDAVGSNDLALLELETSVVLNANTNPIDLATERPA--AGSQ 149
            .|.|       .:|.|.:|.:|  ::....||:|||.|.::|..:....|:.||.:...  .|:.
Zfish   102 EINR-------TVSVITVHPSY--NNLTNENDIALLHLSSAVTFSNYIRPVCLAAQNSVFPNGTS 157

  Fly   150 IIFSGWGSSQVDGSL--SHVLQVATRQSLSASDCQTELYLQQ--EDLLCLSPVDEDFAGL----- 205
            ...:|||:.|:..:|  ..:||......:....|...|....  .:::|        |||
Zfish   158 SWITGWGNIQLGVNLPAPGILQETMIPVVPNDQCNALLGSGSVTNNMIC--------AGLLQGGR 214

  Fly   206 --CSGDAGAPASYNNQLVGIAAFFVS---GCGSE-QPDGYVDVTQHLEWIN 250
              |.||:|.|......||.:.:...|   ||... .|..|..|:|:..|||
Zfish   215 DTCQGDSGGPMVSKQCLVWVQSGITSWGYGCADPYSPGVYTRVSQYQSWIN 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4653	NP_573150.2	Tryp_SPc	30..252	CDD:238113	71/246 (29%)
CG4653	NP_573150.2	Tryp_SPc	30..249	CDD:214473	68/243 (28%)
prss60.1	NP_001082915.1	Tryp_SPc	33..264	CDD:214473	68/243 (28%)
		Tryp_SPc	34..267	CDD:238113	71/246 (29%)
		Somatomedin_B	349..382	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587837
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840