Protein Alignment CG4653 and PRSS56

DIOPT Version :10

• Sequence 1: NP_573150.2
• Gene: CG4653 / 32650
• FlyBaseID: FBgn0030776
• Length: 254
• Species: Drosophila melanogaster
• Sequence 2: XP_047301387.1
• Gene: PRSS56 / 646960
• HGNCID: 39433
• Length: 635
• Species: Homo sapiens
• Alignment Length: 256
• Identity: 70/256 - (27%)
• Similarity: 107/256 - (41%)
• Gaps: 53/256 - (20%)

  Fly    23 VVQSSRLPAEVGSQPHSISLRRNGVHVCGGALIREKWILTAAHC-----------VSLGGGQQSY 76
            :|..|..|.  |:.|..:.|:..|..:|||.|:...|:||||||           |:|..|.:..
Human   105 IVGGSAAPP--GAWPWLVRLQLGGQPLCGGVLVAASWVLTAAHCFVGAPNELLWTVTLAEGSRGE 167

  Fly    77 PAKSYNVRVGSIQRLTGGQLVPLSKIIIHTNYSSSDAVGSNDLALLELETSVVLNANTNPIDLAT 141
            .|:.                ||:::|:.|..:  ......|||||::|.|.|....:..|:.|..
Human   168 QAEE----------------VPVNRILPHPKF--DPRTFHNDLALVQLWTPVSPGGSARPVCLPQ 214

  Fly   142 E--RPAAGSQIIFSGWGSSQVDGSLSHVLQVATRQSLSASDCQTEL--YLQQEDLLC----LSPV 198
            |  .|.||:....:|||:...||..:..::.|....||...|:..|  .|:...:||    ...|
Human   215 EPQEPPAGTACAIAGWGALFEDGPEAEAVREARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGV 279

  Fly   199 DEDFAGLCSGDAGAPASYNNQ-------LVGIAAFFVSGCGSE-QPDGYVDVTQHLEWINE 251
            |.     |.||:|.|.:.:..       |.|:.: :..|||.. :|..|..|....:|:.|
Human   280 DS-----CQGDSGGPLTCSEPGPRPREVLFGVTS-WGDGCGEPGKPGVYTRVAVFKDWLQE 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4653	NP_573150.2	Tryp_SPc	30..252	CDD:238113	68/249 (27%)
PRSS56	XP_047301387.1	Tryp_SPc	105..335	CDD:238113	70/256 (27%)
		PksD	<178..600	CDD:442550	45/165 (27%)