DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4653 and AZU1

DIOPT Version :9

Sequence 1:NP_573150.2 Gene:CG4653 / 32650 FlyBaseID:FBgn0030776 Length:254 Species:Drosophila melanogaster
Sequence 2:NP_001691.1 Gene:AZU1 / 566 HGNCID:913 Length:251 Species:Homo sapiens


Alignment Length:256 Identity:66/256 - (25%)
Similarity:110/256 - (42%) Gaps:32/256 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 SRLLLLVVIVTLGVVQSSRLPAE-----VGSQ-------PHSISLRRNGVHVCGGALIREKWILT 62
            :||.:|.::.  |::.|||..:.     ||.:       |...|::..|.|.||||||..::::|
Human     2 TRLTVLALLA--GLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMT 64

  Fly    63 AAHCV-SLGGGQQSYPAKSYNVRVGSIQRLTGGQLVPLSKIIIHTNYSSSDAVGSNDLALLELET 126
            ||.|. |...|..:....:|::|....|......:..:|:    ..|.....:  |||.||:|:.
Human    65 AASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSE----NGYDPQQNL--NDLMLLQLDR 123

  Fly   127 SVVLNANTN--PIDLATERPAAGSQIIFSGWGSSQVDGSLSHVLQVATRQSLSASDCQTELYLQQ 189
            ...|.::..  |:.|......||::...:||||.:..|.||...:...........|       :
Human   124 EANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQC-------R 181

  Fly   190 EDLLCLSPVDEDFAGLCSGDAGAPASYNNQLVGIAAFFVSGCGSEQPDGYVDVTQHLEWIN 250
            .:.:|...:... .|:|:||.|.|........|:|:|.:..|| ..||.:..|....:||:
Human   182 PNNVCTGVLTRR-GGICNGDGGTPLVCEGLAHGVASFSLGPCG-RGPDFFTRVALFRDWID 240

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4653NP_573150.2 Tryp_SPc 30..252 CDD:238113 59/236 (25%)
Tryp_SPc 30..249 CDD:214473 57/233 (24%)
AZU1NP_001691.1 Tryp_SPc 27..240 CDD:238113 58/227 (26%)
Possesses antibiotic activity. /evidence=ECO:0000269|PubMed:8506327 46..70 12/23 (52%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D469244at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.920

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