Protein Alignment CG4653 and KLK6

DIOPT Version :10

• Sequence 1: NP_573150.2
• Gene: CG4653 / 32650
• FlyBaseID: FBgn0030776
• Length: 254
• Species: Drosophila melanogaster
• Sequence 2: NP_002765.1
• Gene: KLK6 / 5653
• HGNCID: 6367
• Length: 244
• Species: Homo sapiens
• Alignment Length: 254
• Identity: 70/254 - (27%)
• Similarity: 116/254 - (45%)
• Gaps: 33/254 - (12%)

  Fly    12 LLLLVVIVTLGVVQSSRL----PAEVGSQPHSISLRRNGVHVCGGALIREKWILTAAHC------ 66
            :::|.:|......:.::|    |.:..|.|:..:|..:|..:|||.||...|:||||||
Human     5 MVVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQ 69

  Fly    67 VSLGGGQQSYPAKSYNVRVGSIQRLTGGQLVPLSKIIIHTNYSSSDAVGSNDLALLELETSVVLN 131
            |.||         .:|:|    ||.:..:...:.:.:||.:|.:  |....|:.||.|.....|:
Human    70 VFLG---------KHNLR----QRESSQEQSSVVRAVIHPDYDA--ASHDQDIMLLRLARPAKLS 119

  Fly   132 ANTNPIDLATERPAAGSQIIFSGWGSSQVDGSLSHVLQVATRQSLSASDCQTELYLQQ--EDLLC 194
            ....|:.|..:..|..:.....|||.: .||.....:|.|....:|..:|: ..|..|  :::||
Human   120 ELIQPLPLERDCSANTTSCHILGWGKT-ADGDFPDTIQCAYIHLVSREECE-HAYPGQITQNMLC 182

  Fly   195 LSPVDEDFA-GLCSGDAGAPASYNNQLVGIAAFFVSGCGS-EQPDGYVDVTQHLEWINE 251
            ..  ||.:. ..|.||:|.|....:.|.|:.::....||| |:|..|.:|.::..||.:
Human   183 AG--DEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQK 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4653	NP_573150.2	Tryp_SPc	30..252	CDD:238113	67/232 (29%)
KLK6	NP_002765.1	Tryp_SPc	23..237	CDD:214473	65/232 (28%)