Protein Alignment CG4653 and KLK7

DIOPT Version :10

• Sequence 1: NP_573150.2
• Gene: CG4653 / 32650
• FlyBaseID: FBgn0030776
• Length: 254
• Species: Drosophila melanogaster
• Sequence 2: NP_005037.1
• Gene: KLK7 / 5650
• HGNCID: 6368
• Length: 253
• Species: Homo sapiens
• Alignment Length: 254
• Identity: 75/254 - (29%)
• Similarity: 116/254 - (45%)
• Gaps: 32/254 - (12%)

  Fly    12 LLLLVVIVTLG-VVQSSRL----PAEVGSQPHSIS-LRRNGVHVCGGALIREKWILTAAHCVSLG 70
            |||.:.:.|.| ..|..::    |...||.|..:: |..|.:| |||.|:.|:|:||||||
Human    12 LLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLH-CGGVLVNERWVLTAAHC---- 71

  Fly    71 GGQQSYPAKSYNVRVGSIQRLTGG----QLVPLSKIIIHTNYSSSDAVGSNDLALLELETSVVLN 131
                  ....|.|.:||.   |.|    |.:..||...|..||:...|  |||.|::|.:...|:
Human    72 ------KMNEYTVHLGSD---TLGDRRAQRIKASKSFRHPGYSTQTHV--NDLMLVKLNSQARLS 125

  Fly   132 ANTNPIDLATERPAAGSQIIFSGWG-SSQVDGSLSHVLQVATRQSLSASDCQTELY--LQQEDLL 193
            :....:.|.:.....|:....|||| ::..|.:....|.....:.:|..|| |::|  |.:..:|
Human   126 SMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDC-TKVYKDLLENSML 189

  Fly   194 CLSPVDEDFAGLCSGDAGAPASYNNQLVGIAAFFVSGCGS-EQPDGYVDVTQHLEWINE 251
            | :.:.:.....|:||:|.|......|.|:.::....||. ..|..|..|.:..:|||:
Human   190 C-AGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWIND 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4653	NP_573150.2	Tryp_SPc	30..252	CDD:238113	69/231 (30%)
KLK7	NP_005037.1	Tryp_SPc	29..245	CDD:214473	66/233 (28%)