Protein Alignment CG4653 and PROC

DIOPT Version :10

• Sequence 1: NP_573150.2
• Gene: CG4653 / 32650
• FlyBaseID: FBgn0030776
• Length: 254
• Species: Drosophila melanogaster
• Sequence 2: XP_024308771.1
• Gene: PROC / 5624
• HGNCID: 9451
• Length: 556
• Species: Homo sapiens
• Alignment Length: 221
• Identity: 64/221 - (28%)
• Similarity: 104/221 - (47%)
• Gaps: 32/221 - (14%)

  Fly    50 CGGALIREKWILTAAHCVSLGGGQQSYPAKSYNVRVG--SIQRLTGGQL-VPLSKIIIHTNYSSS 111
            ||..||...|:||||||:.        .:|...||:|  .::|....:| :.:.::.:|.|||.|
Human   333 CGAVLIHPSWVLTAAHCMD--------ESKKLLVRLGEYDLRRWEKWELDLDIKEVFVHPNYSKS 389

  Fly   112 DAVGSNDLALLELETSVVLNANTNPIDL------ATERPAAGSQIIFSGWG-----SSQVDGSLS 165
            ..  .||:|||.|.....|:....||.|      ..|...||.:.:.:|||     ..:...:.:
Human   390 TT--DNDIALLHLAQPATLSQTIVPICLPDSGLAERELNQAGQETLVTGWGYHSSREKEAKRNRT 452

  Fly   166 HVLQVATRQSLSASDCQTEL-YLQQEDLLCLSPVDEDFAGLCSGDAGAP--ASYNNQ--LVGIAA 225
            .||.......:..::|...: .:..|::|| :.:..|....|.||:|.|  ||::..  |||:.:
Human   453 FVLNFIKIPVVPHNECSEVMSNMVSENMLC-AGILGDRQDACEGDSGGPMVASFHGTWFLVGLVS 516

  Fly   226 FFVSGCGSEQPDG-YVDVTQHLEWIN 250
             :..|||.....| |..|:::|:||:
Human   517 -WGEGCGLLHNYGVYTKVSRYLDWIH 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4653	NP_573150.2	Tryp_SPc	30..252	CDD:238113	64/221 (29%)
PROC	XP_024308771.1	GLA	85..148	CDD:214503
		EGF_CA	162..193	CDD:238011
		FXa_inhibition	235..270	CDD:464251
		Tryp_SPc	308..543	CDD:238113	64/221 (29%)