DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4653 and Prss53

DIOPT Version :9

Sequence 1:	NP_573150.2	Gene:	CG4653 / 32650	FlyBaseID:	FBgn0030776	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	XP_006230384.1	Gene:	Prss53 / 499270	RGDID:	1566127	Length:	591	Species:	Rattus norvegicus

Alignment Length:	324	Identity:	80/324 - (24%)
Similarity:	120/324 - (37%)	Gaps:	98/324 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 QSYSHSRLLLLVVIVTLGVVQSSRL----------PAE----VGSQPHSISLRRNGVHVCGGALI 55
            ||:....|::..|||..|:..:.|.          |.|    .|..|...|:||.|||:|.|:|:
  Rat     3 QSWGPELLIVGAVIVIEGLQAAQRACGQRGPGPPEPQEGNTLPGEWPWQASVRRQGVHICSGSLV 67

  Fly    56 REKWILTAAHCVSLGGGQQSYPAKSYNVRVGSIQR---LTGGQLVPLSKIII---HTNYSSSDAV 114
            .:.|:||||||..   ...:....|::|.:||:::   ..|.:.|.::.:.:   :.:||.
  Rat    68 ADTWVLTAAHCFE---KMATAELSSWSVVLGSLKQEGLSPGAEEVGVAALQLPKAYNHYSQ---- 125

  Fly   115 GSNDLALLELETSVVLNANTNPI---DLATERPA----AGSQIIFSGWGSSQVDGSL-------- 164
             .:|||||:|         |:||   .|...:|.    .|:....:||..:..||..
  Rat   126 -GSDLALLQL---------THPIVHTTLCLPQPTHHFPFGASCWATGWDQNTSDGKYCPRHKSRE 180

  Fly   165 SHVLQVATRQSLSASDCQTE-----------------------------LYLQQEDLLCLSP--- 197
            |....|.|..:| .|.|.:|                             ||.:....|..:|
  Rat   181 SQTGSVLTVLAL-CSHCVSELDSTLSPLPVSRTLRNLRLRLISRPTCNCLYNRLHQRLLANPARS 244

  Fly   198 ------VDEDFAGLCSGDAGAPASYNNQ-----LVGIAAFFVSGCGSEQ-PDGYVDVTQHLEWI 249
                  ......|.|.||:|.|......     .|||.: |.|.|..|. |....|:..|..|:
  Rat   245 GMLCGGAQPGVQGPCQGDSGGPVMCREPDGHWVQVGIIS-FTSNCAQEDTPVLLTDMAAHSSWL 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4653	NP_573150.2	Tryp_SPc	30..252	CDD:238113	72/289 (25%)
CG4653	NP_573150.2	Tryp_SPc	30..249	CDD:214473	71/287 (25%)
Prss53	XP_006230384.1	Tryp_SPc	45..310	CDD:238113	70/282 (25%)
Prss53	XP_006230384.1	Tryp_SPc	341..561	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.100