DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4653 and Prss36

DIOPT Version :9

Sequence 1:	NP_573150.2	Gene:	CG4653 / 32650	FlyBaseID:	FBgn0030776	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	XP_038942639.1	Gene:	Prss36 / 497040	RGDID:	1593186	Length:	874	Species:	Rattus norvegicus

Alignment Length:	299	Identity:	88/299 - (29%)
Similarity:	127/299 - (42%)	Gaps:	52/299 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SPVQSYSHSRLLLLVVIVTLGVVQ---------------------SSRL----PAEVGSQPHSIS 41
            |.:|::....|:..||..|.|..|                     |||:    .|..|:.|..:|
  Rat    11 SSLQTFLTPHLVFSVVSPTPGAFQDSAVSPTQGEFEDLDCGRPEPSSRIVGGSDAHPGTWPWQVS 75

  Fly    42 LRRNGVHVCGGALIREKWILTAAHCVSLGGGQQSYPAKSYNVRVGSIQR---LTGGQLVPLSKII 103
            |...|.|:|||:||...|:|:||||....|..:  ||..::|.:|...:   |.|..:..::.|:
  Rat    76 LHHGGGHICGGSLIAPSWVLSAAHCFVTNGTLE--PADEWSVLLGVHSQDGPLEGAHMRSVATIL 138

  Fly   104 IHTNYSSSDAVGSNDLALLELETSVVLNANTNPIDL--ATERPAAGSQIIFSGWGSSQVDGSL-- 164
            :..|||..: :|: |||||.|.:...|..:..|:.|  |:...|.|:....:|||..|....|
  Rat   139 VPDNYSRVE-LGA-DLALLRLASPAKLGPSVKPVCLPRASHLFAHGTACWATGWGDVQESDPLPV 201

  Fly   165 SHVLQVATRQSLSASDCQT--------ELYLQ-QEDLLCLSPVDEDFAGLCSGDAGAPASYNNQ- 219
            ..|||....:.|..:.||.        .|.|| ...:|| :...|.....|.||:|.|....:.
  Rat   202 PWVLQEVELKLLGETACQCLYSRPGPFNLTLQLLPGMLC-AGYPEGRRDTCQGDSGGPLVCEDGG 265

  Fly   220 ---LVGIAAFFVSGCGSEQPDGYVDVTQHLE-WINENAV 254
               |.||.:|.. |||.....|......|.| ||.|:.:
  Rat   266 RWFLAGITSFGF-GCGRRNRPGVFTAVAHYESWIREHVM 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4653	NP_573150.2	Tryp_SPc	30..252	CDD:238113	76/242 (31%)
CG4653	NP_573150.2	Tryp_SPc	30..249	CDD:214473	74/239 (31%)
Prss36	XP_038942639.1	Tryp_SPc	59..301	CDD:238113	76/247 (31%)
		Tryp_SPc	338..532	CDD:419748
		Tryp_SPc	607..802	CDD:419748
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.100