Protein Alignment CG4653 and ACR

DIOPT Version :10

• Sequence 1: NP_573150.2
• Gene: CG4653 / 32650
• FlyBaseID: FBgn0030776
• Length: 254
• Species: Drosophila melanogaster
• Sequence 2: NP_001088.2
• Gene: ACR / 49
• HGNCID: 126
• Length: 421
• Species: Homo sapiens
• Alignment Length: 264
• Identity: 70/264 - (26%)
• Similarity: 108/264 - (40%)
• Gaps: 72/264 - (27%)

  Fly    31 AEVGSQPHSISLR-----RNGVHVCGGALIREKWILTAAHCVSLGGGQQSYPAKSYNVR----VG 86
            |:.|:.|..:||:     .:..|.|||:|:..:|:||||||         :..|: ||.    |.
Human    49 AQHGAWPWMVSLQIFTYNSHRYHTCGGSLLNSRWVLTAAHC---------FVGKN-NVHDWRLVF 103

  Fly    87 SIQRLTGGQLVP---------LSKIIIHTNYSSSDAVGSNDLALLELETSVVLNANTNPIDLATE 142
            ..:.:|.|...|         :.|||||..|:|  |...||:||:|:...:.......|..|...
Human   104 GAKEITYGNNKPVKAPLQERYVEKIIIHEKYNS--ATEGNDIALVEITPPISCGRFIGPGCLPHF 166

  Fly   143 RPA--AGSQIIF-SGWGSSQVDGSLSHVLQVATRQSLSASDCQTELYLQQEDL-LCLS------- 196
            :..  .|||..: :|||         ::.:.|.|.|....:.:.:|.    || ||.|
Human   167 KAGLPRGSQSCWVAGWG---------YIEEKAPRPSSILMEARVDLI----DLDLCNSTQWYNGR 218

  Fly   197 ----------PVDEDFAGLCSGDAGAPASYNNQ------LVGIAAFFVSGCGSEQPDGYVDVTQH 245
                      ||.:  ...|.||:|.|....:.      :|||.::.|....:::|..|.....:
Human   219 VQPTNVCAGYPVGK--IDTCQGDSGGPLMCKDSKESAYVVVGITSWGVGCARAKRPGIYTATWPY 281

  Fly   246 LEWI 249
            |.||
Human   282 LNWI 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4653	NP_573150.2	Tryp_SPc	30..252	CDD:238113	70/264 (27%)
ACR	NP_001088.2	Tryp_SPc	42..285	CDD:214473	68/262 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	297..316
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..383
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	397..421